Thiolated Layered Double Hydroxide-Based Nanoparticles: A Study on Mucoadhesiveness and Cytotoxicity

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер unknown, С. 135461 - 135461

Опубликована: Сен. 1, 2024

Язык: Английский

---

Two-dimensional nanomaterials based on rare earth elements for biomedical applications

Chemical Science, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Two-dimensional rare earth-containing nanomaterials are promising candidates in biomedical applications such as drug delivery, bio-imaging, antibacterial and cancer treatment due to their unique structure versatile energy levels.

Язык: Английский

---

A highly sensitive dual-mode detection platform based on the novel copper/molybdenum bimetallic nanoclusters and Co-Fe layered doubled hydroxide nanozyme for butyrylcholinesterase activity sensing

Talanta, Год журнала: 2024, Номер 282, С. 126973 - 126973

Опубликована: Окт. 2, 2024

Язык: Английский

---

Targeted Nanoprobes Enabled Precision Theranostics in Triple‐Negative Breast Cancer

The Chemical Record, Год журнала: 2025, Номер unknown

Опубликована: Янв. 2, 2025

Triple-negative breast cancer (TNBC) represents a highly aggressive and prognostically unfavorable subtype of cancer, characterized by the absence common hormone receptors, which renders conventional therapies largely ineffective. This review comprehensively examines molecular clinical characteristics TNBC, underscoring substantial challenges inherent in its treatment innovative potential targeted nanoprobes advancing both diagnostic therapeutic paradigms. Through modification targeting molecules, can deliver agents specific to TNBC cells, thus significantly improving sensitivity modalities efficacy interventions. Our discussion systematically explores application various molecules their advantages limitations. In addition, this presents series multifunctional that are designed perform functions, providing synergistic approach TNBC. These advanced enable precise tumor localization while monitoring response real time, facilitating more personalized dynamic regimen. The major obstacles encountered during translation discussed detail. use leap forward medicine for current research efforts will continue refine these technologies improve applicability.

Язык: Английский

---

The Opportunities and Challenges of Using Nanomaterials as Photocatalysts for the Degradation of Environmental Pollutants

Comments on Inorganic Chemistry, Год журнала: 2025, Номер unknown, С. 1 - 46

Опубликована: Янв. 22, 2025

Язык: Английский

---

Progress on layered double hydroxides as green materials in sustainable agricultural production

Environmental Research, Год журнала: 2025, Номер unknown, С. 121031 - 121031

Опубликована: Фев. 1, 2025

Язык: Английский

---

Novel photodamage-free bioimaging and anticancer studies using ultra-bright near-infrared emitting nitrogen-doped carbon dots intercalated Zn(OH)2 nanosheets

Chemical Papers, Год журнала: 2025, Номер unknown

Опубликована: Фев. 19, 2025

Язык: Английский

---

Whole‐Component Antigen Nanovaccines Combined With aTIGIT for Enhanced Innate and Adaptive Anti‐tumor Immunity

Small, Год журнала: 2025, Номер unknown

Опубликована: Фев. 18, 2025

Abstract Using entire tumor cells or tissues that display both common and patient‐specific antigens can potentially trigger a comprehensive long‐lasting anti‐tumor immune response. However, the limited immunogenicity, low uptake efficiency, susceptibility to degradation of whole‐component present significant challenges. In this study, we employed lysates (TLs) as antigens, in conjunction with MgAl‐layered double hydroxide (MA) nanoadjuvants Mn 2+ immunostimulants, create personalized MMAT (Mn ‐MA‐TLs) nanovaccines. After subcutaneous injection nanovaccines, high local concentrations TLs facilitated recruitment activation antigen‐presenting (APCs), thereby inducing robust adaptive Remarkably, nanovaccines enabled lysosomal escape, enhanced antigen cross‐presentation, activated cyclic GMP‐AMP synthase (cGAS)‐stimulator interferon genes (STING) pathway APCs. Furthermore, when combined anti‐TIGIT monoclonal antibody (aTIGIT), an checkpoint inhibitor, not only stimulated T‐cell‐based responses but also NK‐cell‐based innate immunity, effectively suppressing growth, recurrence, metastasis. Thus, ternary developed here introduced pioneered paradigm for rapid preparation immunostimulants into offering new prospects clinical immunotherapies.

Язык: Английский

---

MgMn-LDHzyme assisted electrochemical sensor for high-performance point-of-care detection of adrenaline in urine and sweat

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113711 - 113711

Опубликована: Апрель 1, 2025

Язык: Английский

---

LDHzyme-assisted high-performance on-site tracking of levodopa pharmacokinetics for Parkinson’s disease management

Biosensors and Bioelectronics, Год журнала: 2024, Номер 268, С. 116926 - 116926

Опубликована: Ноя. 9, 2024

Язык: Английский

---