Layered double hydroxide nanozyme (LDHzyme)-assisted high-performance electrochemical analysis of organ transplant therapeutic drug concentration DOI

Z Li,

Meng Yin, Xiaoxue Wang

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 207, P. 111969 - 111969

Published: Oct. 22, 2024

Language: Английский

Thiolated Layered Double Hydroxide-Based Nanoparticles: A Study on Mucoadhesiveness and Cytotoxicity DOI
Sema Şentürk, Özlem Kaplan, Kevser Bal

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: unknown, P. 135461 - 135461

Published: Sept. 1, 2024

Language: Английский

Citations

4
Targeted Nanoprobes Enabled Precision Theranostics in Triple‐Negative Breast Cancer DOI Open Access
Ke Ma, Meng Yin, Kezheng Chen

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Triple-negative breast cancer (TNBC) represents a highly aggressive and prognostically unfavorable subtype of cancer, characterized by the absence common hormone receptors, which renders conventional therapies largely ineffective. This review comprehensively examines molecular clinical characteristics TNBC, underscoring substantial challenges inherent in its treatment innovative potential targeted nanoprobes advancing both diagnostic therapeutic paradigms. Through modification targeting molecules, can deliver agents specific to TNBC cells, thus significantly improving sensitivity modalities efficacy interventions. Our discussion systematically explores application various molecules their advantages limitations. In addition, this presents series multifunctional that are designed perform functions, providing synergistic approach TNBC. These advanced enable precise tumor localization while monitoring response real time, facilitating more personalized dynamic regimen. The major obstacles encountered during translation discussed detail. use leap forward medicine for current research efforts will continue refine these technologies improve applicability.

Language: Английский

Citations

0
The Opportunities and Challenges of Using Nanomaterials as Photocatalysts for the Degradation of Environmental Pollutants DOI
Jamshid Khan, Israf Ud Din, Abdulrahman I. Alharthi

et al.

Comments on Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 46

Published: Jan. 22, 2025

Language: Английский

Citations

0
Progress on layered double hydroxides as green materials in sustainable agricultural production DOI
Tongtong Zhang, Zhenghong Xu,

Zhihua Xu

et al.

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121031 - 121031

Published: Feb. 1, 2025

Language: Английский

Citations

0
Novel photodamage-free bioimaging and anticancer studies using ultra-bright near-infrared emitting nitrogen-doped carbon dots intercalated Zn(OH)2 nanosheets DOI
G. Gnanamani Simiyon,

B. Nivetha,

T. Mary Vergheese

et al.

Chemical Papers, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Language: Английский

Citations

0
Whole‐Component Antigen Nanovaccines Combined With aTIGIT for Enhanced Innate and Adaptive Anti‐tumor Immunity DOI Open Access
Weitao Wang, Haitao Wu,

Xuan Zhang

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Abstract Using entire tumor cells or tissues that display both common and patient‐specific antigens can potentially trigger a comprehensive long‐lasting anti‐tumor immune response. However, the limited immunogenicity, low uptake efficiency, susceptibility to degradation of whole‐component present significant challenges. In this study, we employed lysates (TLs) as antigens, in conjunction with MgAl‐layered double hydroxide (MA) nanoadjuvants Mn 2+ immunostimulants, create personalized MMAT (Mn ‐MA‐TLs) nanovaccines. After subcutaneous injection nanovaccines, high local concentrations TLs facilitated recruitment activation antigen‐presenting (APCs), thereby inducing robust adaptive Remarkably, nanovaccines enabled lysosomal escape, enhanced antigen cross‐presentation, activated cyclic GMP‐AMP synthase (cGAS)‐stimulator interferon genes (STING) pathway APCs. Furthermore, when combined anti‐TIGIT monoclonal antibody (aTIGIT), an checkpoint inhibitor, not only stimulated T‐cell‐based responses but also NK‐cell‐based innate immunity, effectively suppressing growth, recurrence, metastasis. Thus, ternary developed here introduced pioneered paradigm for rapid preparation immunostimulants into offering new prospects clinical immunotherapies.

Language: Английский

Citations

0
MgMn-LDHzyme assisted electrochemical sensor for high-performance point-of-care detection of adrenaline in urine and sweat DOI

Z Li,

Ting Liu, Chenyu Wang

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113711 - 113711

Published: April 1, 2025

Language: Английский

Citations

0
Two-dimensional nanomaterials based on rare earth elements for biomedical applications DOI Creative Commons
Mingjun Bai, Hao Wan, Ying Zhang

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Two-dimensional rare earth-containing nanomaterials are promising candidates in biomedical applications such as drug delivery, bio-imaging, antibacterial and cancer treatment due to their unique structure versatile energy levels.

Language: Английский

Citations

2
A highly sensitive dual-mode detection platform based on the novel copper/molybdenum bimetallic nanoclusters and Co-Fe layered doubled hydroxide nanozyme for butyrylcholinesterase activity sensing DOI

Jianxin Qiang,

Chenyu Zhou, Bo Wang

et al.

Talanta, Journal Year: 2024, Volume and Issue: 282, P. 126973 - 126973

Published: Oct. 2, 2024

Language: Английский

Citations

1
LDHzyme-assisted high-performance on-site tracking of levodopa pharmacokinetics for Parkinson’s disease management DOI
Dawei Zhou, Meng Yin,

Yun Shen

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 268, P. 116926 - 116926

Published: Nov. 9, 2024

Language: Английский

Citations

1