Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 97, С. 105753 - 105753
Опубликована: Май 8, 2024
Язык: Английский
International Journal of Pharmaceutics X, Год журнала: 2024, Номер 8, С. 100265 - 100265
Опубликована: Июнь 26, 2024
Cancer remains a major global health challenge, and despite available treatments, its prognosis poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These exhibit remarkable capabilities in targeted controlled release. Their inherent characteristics, such as high surface area-to-volume ratio, make them attractive candidates delivery applications. Smart can release drugs response specific stimuli, including pH, temperature, magnetic fields, light. This unique feature not only reduces side effects but also enhances the overall efficiency of systems. Electrospinning, widely used method, allows precision fabrication smart nanofibers. Its advantages include efficiency, user-friendliness, ability control various manufacturing parameters. In this review, we explore latest developments producing electrospun treatment. Additionally, discuss materials these critical parameters involved electrospinning process.
Язык: Английский
Процитировано
18
Progress in Materials Science, Год журнала: 2024, Номер unknown, С. 101376 - 101376
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
17
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(17), С. 9556 - 9556
Опубликована: Сен. 3, 2024
Personal protective equipment (PPE) has attracted more attention since the outbreak of epidemic in 2019. Advanced nano techniques, such as electrospinning, can provide new routes for developing novel PPE. However, electrospun antibacterial PPE is not easily obtained. Fibers loaded with photosensitizers prepared using single-fluid electrospinning have a relatively low utilization rate due to influence embedding and their inadequate mechanical properties. For this study, monolithic nanofibers core–shell were compared. Monolithic F1 fibers comprising polyethylene oxide (PEO), poly(vinyl alcohol-co-ethylene) (PVA-co-PE), photo-antibacterial agent vitamin K3 (VK3) created blending process. Core–shell F2 coaxial which extensible material PEO was set core section, composite consisting PEO, PVA-co-PE, VK3 shell section. Both designed structural properties had an average diameter approximately 1.0 μm, determined scanning electron microscopy transmission microscopy. amorphously dispersed within polymeric matrices compatible manner, revealed X-ray diffraction Fourier transform infrared spectroscopy. higher tensile strength 2.917 ± 0.091 MPa, whereas longer elongation break 194.567 0.091%. Photoreaction tests showed that, adjustment, could produce 0.222 μmol/L ·OH upon illumination. slightly better performance than fibers, inhibition zones 1.361 0.012 cm 1.296 0.022 E. coli S. aureus, respectively, but less VK3. The intentional tailoring components compositions nanostructures improve process–structure–performance relationship potential sunlight-activated
Язык: Английский
Процитировано
16
Micromachines, Год журнала: 2024, Номер 15(10), С. 1226 - 1226
Опубликована: Сен. 30, 2024
Non-invasive medical nanofiber technology, characterized by its high specific surface area, biocompatibility, and porosity, holds significant potential in various domains, including tissue repair biosensing. It is increasingly becoming central to healthcare offering safer more efficient treatment options for contemporary medicine. Numerous studies have explored non-invasive nanofibers recent years, yet a comprehensive overview of the field remains lacking. In this paper, we provide summary applications electrospun fields, considering multiple aspects perspectives. Initially, introduce electrospinning nanofibers. Subsequently, detail their health, health monitoring, personal protection, thermal regulation, wound care, highlighting critical role improving human health. Lastly, paper discusses current challenges associated with offers insights into future development trajectories.
Язык: Английский
Процитировано
12
Membranes, Год журнала: 2024, Номер 14(5), С. 95 - 95
Опубликована: Апрель 23, 2024
The skin, as the largest organ, serves a protective barrier against external stimuli. However, when skin is injured, wound healing becomes complex process influenced by physiological conditions, bacterial infections, and inflammation. To improve of healing, variety dressings with antibacterial qualities have been created. Electrospun nanofibers gained significant attention in dressing research due to their large specific surface area unique structure. One interesting method for creating Janus-structured side-by-side electrospinning. This work used electrospinning make cellulose acetate/gelatin Janus nanofibers. Curcumin zinc oxide nanoparticles were added these We studied nanofibers' physicochemical characteristics abilities regulate small-molecule medication release. coated curcumin also tested activity. specified successfully fabricated. Nanofibers released medicines controlled manner. Additionally, loaded exhibited excellent capabilities. contributes development advanced promoting combating infections.
Язык: Английский
Процитировано
9
Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown
Опубликована: Янв. 13, 2025
Abstract This review explores the pivotal roles of two advanced nanotechnologies—electrospinning (ES) and fluorescent organic nano-dots (FONs) in development application organoluminophores (OLs). As demand intensifies for innovative OL-based systems fields such as biomedical imaging, drug delivery, materials engineering, sensing, energy, ES FONs present complementary yet distinct technological pathways. Each method offers unique advantages optimizing material properties, compatibility, optical performance, positioning them at forefront research. enables precise control over structure, enhancing performance scalable industrial applications. deliver superior particularly bio-imaging, through environmentally friendly synthesis. comparative analysis critically examines strengths limitations both techniques, including aspects synthesis complexity, adaptability, functional enhancement, utilization. Furthermore, recent advancements, ongoing challenges, future prospects within this rapidly evolving field are discussed, providing a comprehensive perspective on potential these luminescent technologies to drive next-generation OL Graphical
Язык: Английский
Процитировано
1
Solar Energy Materials and Solar Cells, Год журнала: 2024, Номер 275, С. 113020 - 113020
Опубликована: Июль 4, 2024
Язык: Английский
Процитировано
7
Nano Energy, Год журнала: 2024, Номер 131, С. 110203 - 110203
Опубликована: Сен. 6, 2024
Язык: Английский
Процитировано
4
Expert Opinion on Drug Delivery, Год журнала: 2025, Номер unknown, С. 1 - 20
Опубликована: Янв. 7, 2025
Introduction The pursuit of linear dosage in pharmacy is essential for achieving consistent therapeutic release and enhancing patient compliance. This review provides a comprehensive summary zero-order drug delivery systems, with particular focus on reservoir-based systems emanated from different microfabrication technologies.
Язык: Английский
Процитировано
0
Journal of Applied Polymer Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 31, 2025
ABSTRACT Core‐shell nanofibers have the potential to surpass traditional monolithic electrospun in drug delivery, due their ability encapsulate sensitive therapeutics within core, protect them from degradation, and enable controlled release profiles through shell. When designed be stimuli‐responsive, these evolve “smart” delivery platforms for advanced therapeutic applications. This mini‐review examines recent advancements fabrication applications of stimuli‐responsive core‐shell nanofibers. Key techniques, such as coaxial electrospinning, single‐nozzle electrospinning using water‐in‐oil or oil‐in‐water emulsions immiscible blends (e.g., polyethylene oxide chitosan; polyvinylpyrrolidone polyvinylidene), needleless post‐fabrication coating methods, are discussed along with respective advantages limitations. Additionally, review also explores how can engineered respond stimuli like near‐infrared (NIR) light, ultrasound, temperature, pH changes. Representative examples illustrate reduce initial burst release, on‐demand chemodrug implement photothermal therapy against cancer cells. At end, we offer perspectives on challenges, opportunities, new directions future development.
Язык: Английский
Процитировано
0