Organic Letters, Год журнала: 2025, Номер 27(4), С. 961 - 966

Опубликована: Янв. 21, 2025

An electrochemical strategy for the regioselective construction of seleno-benzothiophenes/furans is reported through selenocyclization, followed by Wagner-Meerwein rearrangement. This electro-oxidative tandem process operates under metal-free and external chemical oxidant-free conditions. Advantageously, unprotected homopropargyl alcohols were found to be compatible reaction conditions, releasing water dihydrogen as biproduct. methodology reveals good functional group tolerance, allowing a broad spectrum substrate scopes up 87% isolated yield.

Язык: Английский