Clinical Comparison of the COVID Waves 2-5. An Inpatient Retrospective Comparative Analysis from Karachi, Pakistan
Open Forum Infectious Diseases,
Год журнала:
2025,
Номер
12(3)
Опубликована: Фев. 7, 2025
Abstract
Background
Each
coronavirus
disease
2019
(COVID-19)
wave
is
unique
in
its
clinical
presentation
and
outcome.
In
this
study,
we
compared
the
characteristics
outcomes
of
COVID
waves
2–5
inpatient
settings.
Methods
A
retrospective
study
was
conducted
at
Sindh
Infectious
Diseases
Hospital
Research
Center
on
adult
patients
who
were
admitted
with
a
positive
polymerase
chain
reaction
from
July
2020
to
March
2022.
SPSS
26
used
analyze
data.
Results
total
3190
COVID-19
admitted.
Wave
2
had
highest
percentage
discharges
mortality
(81%;
P
=
.0001).
Cytokine
release
syndrome
most
common
3
(32.7%;
Severe
admission
predominant
4
(79.4%;
.0001),
rates
intubation
(27.1%;
septic
shock
(24.3%;
progression
(50.8%;
5,
majority
elderly
(median
age,
68
years)
mild
(22.4%;
comorbidities
(84.6%;
ratio
acute
kidney
injury
high
(29.2%;
Mortality
lowest
(18.9%;
.0001)
(42.5%;
.0001;
odds
ratio,
3.18;
95%
CI,
2.6–3.8;
2).
Conclusions
some
other
waves,
4,
driven
by
Delta
variant,
being
deadliest
one
terms
severity
outcomes.
Язык: Английский
Allergische Reaktionen auf COVID-19-Impfstoffe – noch relevant?
hautnah,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 31, 2025
Obesity-Related Complications Including Dysglycemia Based on 1-h Post-Load Plasma Glucose in Children and Adolescents Screened before and after COVID-19 Pandemic
Nutrients,
Год журнала:
2024,
Номер
16(15), С. 2568 - 2568
Опубликована: Авг. 5, 2024
Childhood
obesity,
with
its
metabolic
complications,
is
a
problem
of
public
health.
The
International
Diabetes
Federation
(IDF)
has
recommended
glucose
levels
1
h
post
oral
load
(1h-PG)
>
155–209
mg/dL
as
diagnostic
for
intermediate
hyperglycemia
(IH),
while
>209
type
2
diabetes
(T2D).
aim
the
study
was
to
assess
occurrence
prediabetes,
IH,
and
T2D
in
children
adolescents
simple
obesity
according
criteria
American
Association
(ADA)
IDF,
effect
COVID-19
pandemic
on
these
disorders.
Analysis
included
263
screened
either
prepandemic
(PRE—113
cases)
or
post-pandemic
period
(POST—150
cases).
All
underwent
OGTT
measurements
insulin
every
0.5
h,
lipid
profile,
other
tests;
indices
if
resistance
(IR):
HOMA,
QUICKI,
Matsuda
index,
AUC
(glu/ins)
were
calculated.
incidence
T2D,
IH
higher
POST
respect
PRE,
significant
differences
IR,
except
HOMA.
Significant
observed
assessed
parameters
metabolism
among
groups
normal
tolerance
(NGT),
some
similarities
between
(based
1h-PG)
prediabetes.
Increased
frequency
dysglycemia
after
pandemic.
Metabolic
profile
patients
at
1h-PG
“intermediate”
NGT
Язык: Английский