Microcystin congeners in Lake Erie follow the seasonal pattern of nitrogen availability DOI Creative Commons
Justin D. Chaffin, Judy A. Westrick, Laura A. Reitz

и другие.

Harmful Algae, Год журнала: 2023, Номер 127, С. 102466 - 102466

Опубликована: Июнь 2, 2023

Cyanobacteria harmful algal blooms produce many toxic secondary metabolites called cyanotoxins. The most studied group of cyanotoxins are microcystins (MC), with over 300 congeners reported. MC-LR is the congener because its abundance and toxicity. Recent toxicology studies suggest that more hydrophobic MC such as MC-LA, MC-LF, MC-LW may be less abundant but up to seven times than MC-LR, whereas, MC-RR's toxicity only one-fifth MC-LR. Hence, understanding environmental stressors change profile critical assessing negative impact on human health. A two-year field experimental study investigated seasonal spatial changes profiles in western basin Lake Erie. Both showed nitrogen enrichment favored production nitrogen-rich MC-RR (C49H75N13O12). depletion low-nitrogen MC-LA (C46H67N7O12). (a medium N level, C49H75N10O12) accounted for ∼30% 50% total concentration was stable across concentrations. Using relative concentrations each congener, both LC-MS/MS ELISA overestimated early bloom (July) underestimated it late (September). On 24 July 2019, highly MC-LF were detected at nearshore stations exceeding drinking water standards. This demonstrated toxic, high dominated under nitrogen-replete conditions season, whereas nitrogen-limited later season.

Язык: Английский

Foodborne pathogens in the plastisphere: Can microplastics in the food chain threaten microbial food safety? DOI Creative Commons
Raffaella Tavelli, Martijn Callens, Charlotte Grootaert

и другие.

Trends in Food Science & Technology, Год журнала: 2022, Номер 129, С. 1 - 10

Опубликована: Сен. 6, 2022

Microplastics (MPs) contaminate the global marine and terrestrial ecosystems. This environmental contamination can enter food chain, with MPs found in drinking water, fishery products other categories. Consequently, ingestion is considered main route of human exposure to MPs. Concerns exist on potential act as vectors for pathogenic bacteria, possibly threatening microbial safety. Starting from current evidence foodborne pathogens associated MPs, we review state knowledge putative role enhancing harmful bacterial traits transporting them humans. Finally, focus simultaneous uptake gut. Overall, identify major gaps, both mechanisms possible health outcomes. The scarce inconclusive results regarding effect virulence evolution, together insufficient about attachment toxins highlight need further studies. We conclude that biofilm-coated foodstuffs may pose several risks safety, but research will be essential determine extent their health.

Язык: Английский

Процитировано

59

Cyanotoxins uptake and accumulation in crops: Phytotoxicity and implications on human health DOI
Chanusha Weralupitiya, Rasika P. Wanigatunge, D. Gunawardana

и другие.

Toxicon, Год журнала: 2022, Номер 211, С. 21 - 35

Опубликована: Март 11, 2022

Язык: Английский

Процитировано

40

Harmful Cyanobacterial Blooms: Biological Traits, Mechanisms, Risks, and Control Strategies DOI Open Access
Lirong Song, Yunlu Jia, Boqiang Qin

и другие.

Annual Review of Environment and Resources, Год журнала: 2023, Номер 48(1), С. 123 - 147

Опубликована: Сен. 8, 2023

Harmful cyanobacterial blooms (CyanoHABs) impact lakes, estuaries, and freshwater reservoirs worldwide. The duration, severity, spread of CyanoHABs have markedly increased over the past decades will likely continue to increase. This article addresses universal phenomena occurring in many ecosystems Based on analysis ecophysiological traits bloom-forming cyanobacteria their interactions with environmental processes, we summarize decipher driving forces leading initiation, outbreak, persistence blooms. Due coupling effects eutrophication, rising CO 2 levels global warming, a multidisciplinary joint research approach is critical for better understanding CyanoHAB phenomenon its prediction, remediation, prevention. There an urgent need evaluate guide proper use bloom control techniques at large scales, using science-based environmentally friendly approaches.

Язык: Английский

Процитировано

40

Oxidative Stress, Reductive Stress and Antioxidants in Vascular Pathogenesis and Aging DOI Creative Commons
Mitko Mladenov, Lubomir T. Lubomirov, Olaf Grisk

и другие.

Antioxidants, Год журнала: 2023, Номер 12(5), С. 1126 - 1126

Опубликована: Май 19, 2023

This review is focused on the mechanisms that regulate health, disease and aging redox status, signal pathways counteract oxidative reductive stress, role of food components additives with antioxidant properties (curcumin, polyphenols, vitamins, carotenoids, flavonoids, etc.), hormones irisin melatonin in homeostasis animal human cells. The correlations between deviation from optimal conditions inflammation, allergic, autoimmune responses are discussed. Special attention given to vascular system, kidney, liver brain stress processes. hydrogen peroxide as an intracellular paracrine molecule also reviewed. cyanotoxins β-N-methylamino-l-alanine (BMAA), cylindrospermopsin, microcystins nodularins introduced potentially dangerous environment pro-oxidants.

Язык: Английский

Процитировано

33

Microcystin congeners in Lake Erie follow the seasonal pattern of nitrogen availability DOI Creative Commons
Justin D. Chaffin, Judy A. Westrick, Laura A. Reitz

и другие.

Harmful Algae, Год журнала: 2023, Номер 127, С. 102466 - 102466

Опубликована: Июнь 2, 2023

Cyanobacteria harmful algal blooms produce many toxic secondary metabolites called cyanotoxins. The most studied group of cyanotoxins are microcystins (MC), with over 300 congeners reported. MC-LR is the congener because its abundance and toxicity. Recent toxicology studies suggest that more hydrophobic MC such as MC-LA, MC-LF, MC-LW may be less abundant but up to seven times than MC-LR, whereas, MC-RR's toxicity only one-fifth MC-LR. Hence, understanding environmental stressors change profile critical assessing negative impact on human health. A two-year field experimental study investigated seasonal spatial changes profiles in western basin Lake Erie. Both showed nitrogen enrichment favored production nitrogen-rich MC-RR (C49H75N13O12). depletion low-nitrogen MC-LA (C46H67N7O12). (a medium N level, C49H75N10O12) accounted for ∼30% 50% total concentration was stable across concentrations. Using relative concentrations each congener, both LC-MS/MS ELISA overestimated early bloom (July) underestimated it late (September). On 24 July 2019, highly MC-LF were detected at nearshore stations exceeding drinking water standards. This demonstrated toxic, high dominated under nitrogen-replete conditions season, whereas nitrogen-limited later season.

Язык: Английский

Процитировано

28