Placenta, Год журнала: 2024, Номер 155, С. 42 - 51
Опубликована: Авг. 5, 2024
Язык: Английский
Placenta, Год журнала: 2024, Номер 155, С. 42 - 51
Опубликована: Авг. 5, 2024
Язык: Английский
NeuroToxicology, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1JAMA Network Open, Год журнала: 2024, Номер 7(10), С. e2440301 - e2440301
Опубликована: Окт. 18, 2024
Despite an increase in maternal prenatal cannabis use and associations with adverse neonatal outcomes, research on child neurodevelopmental outcomes is limited.
Язык: Английский
Процитировано
2Antioxidants, Год журнала: 2024, Номер 13(11), С. 1284 - 1284
Опубликована: Окт. 24, 2024
The endoplasmic reticulum (ER) is the organelle mainly involved in maintaining cellular homeostasis and driving correct protein folding. ER-dependent defects or dysfunctions are associated with genesis/progression of several pathological conditions, including cancer, inflammation, neurodegenerative disorders, that directly indirectly correlated to a wide set events collectively named under term "ER stress". Despite recent increase interest concerning ER activity, further research studies needed highlight all mechanisms responsible for failure. In this field, discoveries paved way comprehension strong interaction between stress development endocannabinoid system. activity system mediated by activation cannabinoid receptors (CB), G protein-coupled induce decrease cAMP levels, downstream anti-inflammatory effects. CB drives, most cases, recovery through regulation hallmarks PERK, ATF6, IRE1. review, we focus on role modulating stress, particular attention processes leading UPR oxidative response extinguishment, underlying natural cannabinoids' modulation complex machine.
Язык: Английский
Процитировано
2Placenta, Год журнала: 2024, Номер 155, С. 42 - 51
Опубликована: Авг. 5, 2024
Язык: Английский
Процитировано
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