Krüppel-like factor 6 involvement in the endoplasmic reticulum homeostasis of extravillous trophoblasts DOI
Lucille T. Kourdova, Andrea L. Miranda,

Milagros Ovejero

et al.

Placenta, Journal Year: 2024, Volume and Issue: 155, P. 42 - 51

Published: Aug. 5, 2024

Language: Английский

Hippocampal Apoptosis: Molecular Mechanisms Triggered by Toxic Cannabinoid Exposure: A Narrative Review DOI
Habibeh Mashayekhi‐Sardoo,

Mahdiyeh Hedayati-Moghadam,

Yousef Baghcheghi

et al.

NeuroToxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Maternal Prenatal Cannabis Use and Child Autism Spectrum Disorder DOI Creative Commons
Lyndsay A. Avalos,

Mahlet Shenkute,

Stacey E. Alexeeff

et al.

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(10), P. e2440301 - e2440301

Published: Oct. 18, 2024

Despite an increase in maternal prenatal cannabis use and associations with adverse neonatal outcomes, research on child neurodevelopmental outcomes is limited.

Language: Английский

Citations

2
Exploring Endocannabinoid System: Unveiling New Roles in Modulating ER Stress DOI Creative Commons

Ilaria Capolupo,

Maria Rosaria Miranda, Simona Musella

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(11), P. 1284 - 1284

Published: Oct. 24, 2024

The endoplasmic reticulum (ER) is the organelle mainly involved in maintaining cellular homeostasis and driving correct protein folding. ER-dependent defects or dysfunctions are associated with genesis/progression of several pathological conditions, including cancer, inflammation, neurodegenerative disorders, that directly indirectly correlated to a wide set events collectively named under term "ER stress". Despite recent increase interest concerning ER activity, further research studies needed highlight all mechanisms responsible for failure. In this field, discoveries paved way comprehension strong interaction between stress development endocannabinoid system. activity system mediated by activation cannabinoid receptors (CB), G protein-coupled induce decrease cAMP levels, downstream anti-inflammatory effects. CB drives, most cases, recovery through regulation hallmarks PERK, ATF6, IRE1. review, we focus on role modulating stress, particular attention processes leading UPR oxidative response extinguishment, underlying natural cannabinoids' modulation complex machine.

Language: Английский

Citations

1
Krüppel-like factor 6 involvement in the endoplasmic reticulum homeostasis of extravillous trophoblasts DOI
Lucille T. Kourdova, Andrea L. Miranda,

Milagros Ovejero

et al.

Placenta, Journal Year: 2024, Volume and Issue: 155, P. 42 - 51

Published: Aug. 5, 2024

Language: Английский

Citations

0