Mushrooms as future generation healthy foods

Frontiers in Nutrition, Год журнала: 2022, Номер 9

Опубликована: Дек. 6, 2022

The potential of edible mushrooms as an unexploited treasure trove, although rarely included in known food guidelines, is highlighted. Their role shielding people against the side effects unhealthy stylish diet reviewed. Mushrooms complement human with various bioactive molecules not identified or deficient foodstuffs plant and animal sources, being considered a functional for prevention several diseases. have been widely used medicinal products more than 2,000 years, but globally field use wild has untapped. There broad range which remain poorly even unreported valuable pool sources compounds biopharma utilization new dietary supplements. Some unique elements their preventative healthcare are emphasized, through positive impact on immune system. antiviral, anti-inflammatory, anti-neoplastic, other health concerns discussed. incorporate top non-digestible oligosaccharides, ergothioneine, humans unable to synthesize, later antioxidant, cytoprotective, anti-inflammatory element, therapeutic potential, approved by world agencies. prebiotic activity beneficially affects gut homeostasis performance balance microbiota enhanced. Several recent studies neurological contribution growth nerve brain cells mentioned. Indeed, foods' nutraceuticals presently regarded next-generation foods, supporting wellness, promising prophylactic agents.

Язык: Английский

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A Review of Ganoderma Triterpenoids and Their Bioactivities

Biomolecules, Год журнала: 2022, Номер 13(1), С. 24 - 24

Опубликована: Дек. 22, 2022

For centuries,

Язык: Английский

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Fungi as a Source of Edible Proteins and Animal Feed

Journal of Fungi, Год журнала: 2023, Номер 9(1), С. 73 - 73

Опубликована: Янв. 3, 2023

It is expected that the world population will reach 9 billion by 2050. Thus, meat, dairy or plant-based protein sources fail to meet global demand. New solutions must be offered find innovative and alternative sources. As a natural gift, edible wild mushrooms growing in wet shadow places can picked hand have been used as food. From searching forests producing single cell proteins (SCP) small scales mega production, academia, United Nations Organizations, industries, political makers others, play significant roles. Fermented traditional foods also reinvestigated. For example, kefir, miso, tempeh, are an excellent source for fungal isolates production. Fungi unique criteria of consuming various inexpensive wastes carbon energy biomass, concentrate amino acids with minimal requirement other environmental resources (e.g., light water). Fungal fermented SCP consumed either intentionally unintentionally our daily meals many applications food feed industries. This review addresses fungi animal feed, focusing mainly on SCP, mushrooms, foods, safety their consumption.

Язык: Английский

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Endophytic fungi: hidden treasure chest of antimicrobial metabolites interrelationship of endophytes and metabolites

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Июль 11, 2023

Endophytic fungi comprise host-associated fungal communities which thrive within the tissues of host plants and produce a diverse range secondary metabolites with various bioactive attributes. The such as phenols, polyketides, saponins, alkaloids help to mitigate biotic abiotic stresses, fight against pathogen attacks enhance plant immune system. We present an overview association endophytic discuss molecular mechanisms induced during their symbiotic interaction. focuses on (especially those terpenoid nature) secreted by respective function. recent advancement in multi-omics approaches paved way for identification these characterization via comparative analysis extensive omics datasets. This study also elaborates role associated key agricultural crops hence important sustainability agriculture.

Язык: Английский

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Phylogenomics, divergence times and notes of orders in Basidiomycota

Fungal Diversity, Год журнала: 2024, Номер 126(1), С. 127 - 406

Опубликована: Июль 9, 2024

Язык: Английский

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OMICS and Other Advanced Technologies in Mycological Applications

Journal of Fungi, Год журнала: 2023, Номер 9(6), С. 688 - 688

Опубликована: Июнь 19, 2023

Fungi play many roles in different ecosystems. The precise identification of fungi is important aspects. Historically, they were identified based on morphological characteristics, but technological advancements such as polymerase chain reaction (PCR) and DNA sequencing now enable more accurate taxonomy, higher-level classifications. However, some species, referred to "dark taxa", lack distinct physical features that makes their challenging. High-throughput metagenomics environmental samples provide a solution identifying new lineages fungi. This paper discusses approaches including PCR amplification rDNA, multi-loci phylogenetic analyses, the importance various omics (large-scale molecular) techniques for understanding fungal applications. use proteomics, transcriptomics, metatranscriptomics, metabolomics, interactomics provides comprehensive These advanced technologies are critical expanding knowledge Kingdom Fungi, its impact food safety security, edible mushrooms foodomics, secondary metabolites, mycotoxin-producing fungi, biomedical therapeutic applications, antifungal drugs drug resistance, data novel development. also highlights exploring from extreme environments understudied areas identify dark taxa.

Язык: Английский

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Natural Compounds of Fungal Origin with Antimicrobial Activity—Potential Cosmetics Applications

Pharmaceuticals, Год журнала: 2023, Номер 16(9), С. 1200 - 1200

Опубликована: Авг. 23, 2023

The phenomenon of drug resistance in micro-organisms necessitates the search for new compounds capable combating them. Fungi emerge as a promising source such they produce wide range secondary metabolites with bacteriostatic or fungistatic activity. These can serve alternatives commonly used antibiotics. Furthermore, fungi also accumulate antiviral This review focuses on filamentous and macrofungi sources antimicrobial compounds. article describes both individual isolated extracts that exhibit antibacterial, antifungal, are produced by fruiting bodies mycelium, well biomass mycelial cultures. Additionally, this characterizes chemical extracted from mushrooms realm cosmetology; specifically, their

Язык: Английский

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Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

Nutrients, Год журнала: 2024, Номер 16(2), С. 258 - 258

Опубликована: Янв. 15, 2024

Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is congenital blood disorder characterized by considerable phenotypic diversity. It comprises group of disorders, with sickle anemia (SCA) being most prevalent serious genotype. Although there have been some systematic reviews global data, worldwide statistics regarding SCD prevalence, morbidity, mortality remain scarce. In developed countries lower number patients, cutting-edge technologies led to development new treatments. However, developing settings where (SCD) more prevalent, medical management, rather than cure, still relies on use hydroxyurea, transfusions, analgesics. This that affects red cells, consequently affecting organs diverse manners. We discuss its etiology advent technologies, but aim this study understand various types nutrition-related studies involving individuals suffering from SCD, particularly Africa. The interplay environment, food, gut microbiota, along their respective genomes collectively known as microbiome, host metabolism responsible for mediating metabolic phenotypes modulating microbiota. addition, it serves purpose providing essential nutrients. Moreover, engages direct interactions homeostasis immune system, well indirect via metabolites. Nutrition interventions nutritional care are mechanisms addressing increased nutrient expenditures important aspects supportive management patients SCD. Underprivileged areas Sub-Saharan Africa should be accompanied efforts define promote Their importance key maintaining well-being quality life, especially because products limited, while native medicinal plant resources acknowledged.

Язык: Английский

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Biologically active secondary metabolites from white-rot fungi

Frontiers in Chemistry, Год журнала: 2024, Номер 12

Опубликована: Март 13, 2024

In recent years, there has been a considerable rise in the production of novel metabolites derived from fungi compared to ones originating bacteria. These organic substances are utilized various sectors such as farming, healthcare, and pharmaceutical. Since all dividing living cells contain primary metabolites, secondary synthesized by utilizing intermediate compounds or by-products generated metabolic pathways. Secondary not critical for growth development an organism; however, they exhibit variety distinct biological characteristics. White-rot only microorganisms able decompose wood components. Hence, play important role both carbon nitrogen cycles decomposing non-living substrates. They ubiquitous nature, particularly hardwood (e.g., birch aspen) forests. fungi, besides ligninolytic enzymes, produce different bioactive during their metabolism including some with antimicrobial anticancer properties. Such properties could be potential interest pharmaceutical industries. Considering importance untapped biologically active white-rot present paper reviews produced interesting bioactivities.

Язык: Английский

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GC-MS Based Characterization, Antibacterial, Antifungal and Anti-Oncogenic Activity of Ethyl Acetate Extract of Aspergillus niger Strain AK-6 Isolated from Rhizospheric Soil

Current Issues in Molecular Biology, Год журнала: 2023, Номер 45(5), С. 3733 - 3756

Опубликована: Апрель 24, 2023

Rhizospheric soil is the richest niche of different microbes that produce biologically active metabolites. The current study investigated antimicrobial, antifungal and anticancer activities ethyl acetate extract potent rhizospheric fungus Aspergillus niger AK6 (AK-6). A total six fungal isolates were isolated, isolate AK-6 was selected based on primary screening. Further, it exhibited moderate antimicrobial activity against pathogens such as Klebsiella pneumonia, Candida albicans, Escherichia coli, Shigella flexneri, Bacillus subtilis Staphylococcus aureus. morphological molecular characterization (18S rRNA) confirmed belonged to niger. showed with 47.2%, 59.4% 64.1% inhibition Sclerotium rolfsii, Cercospora canescens Fusarium sambucinum phytopathogens. FT-IR analysis displayed biological functional groups. Consequently, GC-MS bioactive compounds, namely, n-didehydrohexacarboxyl-2,4,5-trimethylpiperazine (23.82%), dibutyl phthalate (14.65%), e-5-heptadecanol (8.98%), 2,4-ditert-butylphenol (8.60%), among 15 compounds isolated. MCF-7 cell line human breast adenocarcinoma an IC50 value 102.01 μg/mL. Furthermore, flow cytometry depicted 17.3%, 26.43%, 3.16% early late apoptosis necrosis in extarct treated line, respectively. results present suggest isolated strain has potential be explored a promising drug for medical agricultural applications.

Язык: Английский

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