Animal- and Plant-Based Protein Sources: A Scoping Review of Human Health Outcomes and Environmental Impact

Nutrients, Год журнала: 2022, Номер 14(23), С. 5115 - 5115

Опубликована: Дек. 1, 2022

Dietary proteins are indispensable to human nutrition. In addition their tissue-building function, they affect body composition and regulate various metabolic pathways, as well satiety immune system activity. Protein use can be examined from a quantitative or qualitative viewpoint. this scoping review, we compare animal- plant-based protein sources in terms of effects on health the environment. We conclude that consumption vegetable is associated with better outcomes overall (namely, cardiovascular system) than animal-based product use. The healthier dovetail lower environmental impact, which must considered when designing an optimal diet. Indeed, planet cannot disjointed being. Future research will clarify mechanisms action underlying compared animal sources, fostering agronomic practices influencing public direction benefit both its inhabitants.

Язык: Английский

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The obesity-breast cancer link: a multidisciplinary perspective

Cancer and Metastasis Reviews, Год журнала: 2022, Номер 41(3), С. 607 - 625

Опубликована: Июнь 25, 2022

Abstract Obesity, exceptionally prevalent in the USA, promotes incidence and progression of numerous cancer types including breast cancer. Complex, interacting metabolic immune dysregulation marks development both obesity. Obesity chronic low-grade inflammation, particularly white adipose tissue, which drives dysfunction marked by increased pro-inflammatory cytokine production, alternative macrophage activation, reduced T cell function. Breast tissue is predominantly composed adipose, developing readily directly interacts with cells signals from remodeled This review discusses biological mechanisms through obesity cancer, role health disparities, dietary interventions to mitigate adverse effects on We detail intersection an emphasis shared unique patterns these disease processes. have highlighted key areas biology exacerbated obesity, incidence, progression, therapeutic response. posit that interception obesity-driven will require limit protumor signaling obese consider genetic, structural, social determinants obesity–breast link. Finally, we evidence for various offset clinical preclinical studies In light strong associations between rising rates many parts world, effective, safe, well-tolerated, equitable burden are urgently needed.

Язык: Английский

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The Effects of the Mediterranean Diet on Health and Gut Microbiota

Nutrients, Год журнала: 2023, Номер 15(9), С. 2150 - 2150

Опубликована: Апрель 29, 2023

The Mediterranean Diet (MD) is plant-based and consists of multiple daily portions vegetables, fruit, cereals, olive oil. Although there are challenges with isolating the MD from typical lifestyle culture (including prolonged ‘social’ meals siestas), much evidence supports health benefits that include improved longevity, reduced metabolic risk Diabetes Mellitus, obesity, Metabolic Syndrome, malignancy cardiovascular disease, cognitive function. also associated characteristic modifications to gut microbiota, mediated through its constituent parts (primarily dietary fibres, extra virgin oil, polyunsaturated fatty acids [including ω-3]). These enhanced growth species produce short-chain (butyrate), such as Clostridium leptum Eubacterium rectale, Bifidobacteria, Bacteroides, Faecalibacterium prausnitzii species, Firmicutes Blautia species. Such changes in microbiota known be favourably inflammatory oxidative status, propensity for overall health. A key challenge future explore extent which by microbiota. confers both environmental benefits. Adoption should perhaps encouraged facilitated more generally not just restricted populations regions. However, this approach limited perennial availability some non-Mediterranean regions, intolerability a high-fibre diet people, potential cultural disconnects juxtapose traditional Western) diets MD.

Язык: Английский

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Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review

Nutrients, Год журнала: 2023, Номер 15(5), С. 1104 - 1104

Опубликована: Фев. 22, 2023

Low muscle mass combined with changes in physical function and quality is defined as sarcopenia. In people > 60 years, sarcopenia reaches 10% tends to increase age. Individual nutrients, such protein, may have a protective role against sarcopenia, but recent evidence suggests that protein alone has been ineffective increasing strength. Dietary patterns, instead, high "anti-inflammatory" potential, the Mediterranean dietary pattern, considered an emerging remedy The aim of this systematic review was summarize diet prevention and/or improvement, including data, healthy elders. We searched published studies about until December 2022 Pubmed, Cochrane, Scopus search engine grey literature. total, ten articles were identified relevant: four cross-sectional six prospective. No clinical trial identified. Only three assessed presence measured mass, which essential criterion diagnosis. adherence had, general, positive function, while results less clear regard Additionally, there no effect on There need for conduction trials order reach cause-effects conclusions regarding importance management non-Mediterranean populations.

Язык: Английский

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The Association Between Adherence to the Mediterranean Diet and Depression and Anxiety Symptoms in University Students: The Mediating Role of Lean Mass and the Muscle Strength Index

Nutrients, Год журнала: 2025, Номер 17(2), С. 346 - 346

Опубликована: Янв. 18, 2025

Background/objectives: recent studies have suggested that components typical of the Mediterranean diet (MedDiet) are associated with depression and anxiety prevention. In this sense, main objective study was to analyse associations between adherence MedDiet symptoms examine whether relationship is mediated by lean mass muscle strength index (MSI). Methods: a cross-sectional (based on data obtained from Nuts4Brain-Z study) conducted 2023–2024, involving 428 university students, aged 18–30 years, Spanish public university. Depression assessed using Beck Inventory (BDI-II), via General Anxiety Disorder-7 (GAD-7) tool. Adherence MEDAS questionnaire. Lean bioimpedance, MSI measured dynamometer. ANCOVA models were used test mean differences in scores categories (low < 9 points vs high ≥ points). Serial multiple mediation models, adjusted for confounders, explore role relationships symptoms. Results: students exhibited lower (p 0.05) than did low MedDiet. The analysis preliminarily revealed both acted as mediators anxiety. Conclusion:adherence per se does not appear direct effect because these partially (for depression) or entirely anxiety) explained MSI.

Язык: Английский

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Obesity, metabolic syndrome, and cancer: pathophysiological and therapeutic associations

Endocrine, Год журнала: 2021, Номер 74(3), С. 478 - 497

Опубликована: Окт. 8, 2021

Язык: Английский

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Influence of Olive Oil and Its Components on Breast Cancer: Molecular Mechanisms

Molecules, Год журнала: 2022, Номер 27(2), С. 477 - 477

Опубликована: Янв. 12, 2022

Breast cancer is the most frequent malignant neoplasia and a leading cause of mortality in women worldwide. The Mediterranean diet has been proposed as healthy dietary pattern with protective effects several chronic diseases, including breast cancer. This characterized by consumption abundant plant foods olive oil principal source fat, which considered one main components potential antioxidant, anti-inflammatory anticancer effects. Extra-virgin (EVOO) bioactive compounds, mainly monounsaturated fatty acids, triterpenes polyphenols, such phenolic alcohols (e.g., hydroxytyrosol), secoiridoids oleuropein oleocanthal), lignans pinoresinol) or flavonoids luteolin). While epidemiological evidence still limited, experimental vivo vitro data have shown effect this its compounds on mammary carcinogenesis. Such account through complex multiple mechanisms, changes epigenetics, transcriptome protein expression that modulate signaling pathways. Molecular targets EVOO role acquisition hallmarks. Although further research needed to elucidate their beneficial human prevention progression disease, points context heathy choice, while may be promising adjuvants strategies.

Язык: Английский

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The Role of Diet and Dietary Patterns in Parkinson’s Disease

Nutrients, Год журнала: 2022, Номер 14(21), С. 4472 - 4472

Опубликована: Окт. 25, 2022

Parkinson’s Disease (PD) is a neurodegenerative disorder associated with diminished nutrition status and decreased quality of life. While the prevalence PD expected to increase, no preventative or curative therapy for exists at this time. Although diet represent modifiable risk factors reducing chronic disease risk, research on impact single nutrients has yielded mixed results. As result, single-nutrient approach may be driving force behind inconsistency, holistic dietary overcome inconsistency by accounting interactions between nutrients. The following review aims examine generally healthy pattern, protein-restricted (PRD), ketogenic (KD), Mediterranean (MD), Mediterranean-DASH Intervention Neurodegenerative Delay (MIND) progression, severity. most included studies support role patterns in alleviating severity, inconsistent results need further evidence necessitate more being conducted before making recommendations. Research potential beneficial effects should also investigate risks.

Язык: Английский

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European Head and Neck Society recommendations for head and neck cancer survivorship care

Oral Oncology, Год журнала: 2022, Номер 133, С. 106047 - 106047

Опубликована: Авг. 3, 2022

Язык: Английский

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Low Adherence to Mediterranean Diet Is Associated with Probable Sarcopenia in Community-Dwelling Older Adults: Results from the Longevity Check-Up (Lookup) 7+ Project

Nutrients, Год журнала: 2023, Номер 15(4), С. 1026 - 1026

Опубликована: Фев. 18, 2023

Muscle strength is a relevant metric of aging. Greater adherence to Mediterranean diet associated with better health outcomes across all life stages; however, evidence on the relationship between and muscle in older adults inconclusive. In this study, we evaluated handgrip large sample community-dwelling from Longevity Check-up 7+ project. A total 2963 participants (mean age 72.8 ± 5.7 years; 54.4% women) were analyzed. was using modified Medi-Lite score categorized as low (≤8), good (9 11), or high (≥12). Handgrip normal according cut-points by European Working Group Sarcopenia Older People 2. lower had significantly higher prevalence probable sarcopenia (25.9%) than those (19.1%) (15.5%) adherence. The proportion increased age, but it remained groups. Logistic regression showed that greater risk sarcopenia. female sex, physical inactivity Our findings emphasize positive association healthy lifestyles, including diet, function old age.

Язык: Английский

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