Biosensors, Год журнала: 2024, Номер 14(12), С. 600 - 600

Опубликована: Дек. 7, 2024

In order to identify carcinoembryonic antigen (CEA) in serum samples, an innovative smartphone-based, label-free electrochemical immunosensor was created without the need for additional labels or markers. This technology presents a viable method on-site cancer diagnostics. The novel smartphone-integrated, immunosensing platform constructed by nanostructured materials that utilize layer-by-layer (LBL) assembly technique, allowing meticulous control over interface. Detection relies on direct interactions extra tagging agents, where ordered graphene oxide (GO), carbon nanotubes (CNTs), and copper nanoparticles (CuONPs) were sequentially deposited onto screen-printed electrode (SPCE), designated as CuONPs/CNTs/GO/SPCE. significantly amplifies signal, detection of low concentrations target molecules CEA. LBL approach enables precise construction multi-layered structures sensor surface, enhancing their activity optimizing performance CEA detection. These serve efficient carriers increase surface area, conductivity, structural support antibody loading, thus improving sensitivity this transducer is based decrease current response [Fe(CN)

Язык: Английский