Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode DOI Creative Commons
Supada Khonyoung,

Praphatsorn Mangkronkaew,

Puttaporn Klayprasert

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 600 - 600

Published: Dec. 7, 2024

In order to identify carcinoembryonic antigen (CEA) in serum samples, an innovative smartphone-based, label-free electrochemical immunosensor was created without the need for additional labels or markers. This technology presents a viable method on-site cancer diagnostics. The novel smartphone-integrated, immunosensing platform constructed by nanostructured materials that utilize layer-by-layer (LBL) assembly technique, allowing meticulous control over interface. Detection relies on direct interactions extra tagging agents, where ordered graphene oxide (GO), carbon nanotubes (CNTs), and copper nanoparticles (CuONPs) were sequentially deposited onto screen-printed electrode (SPCE), designated as CuONPs/CNTs/GO/SPCE. significantly amplifies signal, detection of low concentrations target molecules CEA. LBL approach enables precise construction multi-layered structures sensor surface, enhancing their activity optimizing performance CEA detection. These serve efficient carriers increase surface area, conductivity, structural support antibody loading, thus improving sensitivity this transducer is based decrease current response [Fe(CN)

Language: Английский

Mxenes as a versatile nanoplatform: Synthesis and emerging biomedical applications DOI
Ali Mohammad Amani, Ehsan Vafa,

Maryam Mirzae

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

6
Dual-channel, real-time, long-term stable electrochemical immunosensor based on Au, Cu-vertical graphene for detection of carcinoembryonic antigen in tumor cells DOI
Tingting Yao, Wei Li, Hongji Li

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1355, P. 344017 - 344017

Published: April 5, 2025

Language: Английский

Citations

0
A sensitive electrochemiluminescence immunosensor for CEA detection based on the ECL-RET between zinc-based metal–organic frameworks and ZiF-8@PDA DOI
Yige Li, Yingying Cheng,

Haoyi Ren

et al.

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108843 - 108843

Published: Oct. 28, 2024

Language: Английский

Citations

1
Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode DOI Creative Commons
Supada Khonyoung,

Praphatsorn Mangkronkaew,

Puttaporn Klayprasert

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 600 - 600

Published: Dec. 7, 2024

In order to identify carcinoembryonic antigen (CEA) in serum samples, an innovative smartphone-based, label-free electrochemical immunosensor was created without the need for additional labels or markers. This technology presents a viable method on-site cancer diagnostics. The novel smartphone-integrated, immunosensing platform constructed by nanostructured materials that utilize layer-by-layer (LBL) assembly technique, allowing meticulous control over interface. Detection relies on direct interactions extra tagging agents, where ordered graphene oxide (GO), carbon nanotubes (CNTs), and copper nanoparticles (CuONPs) were sequentially deposited onto screen-printed electrode (SPCE), designated as CuONPs/CNTs/GO/SPCE. significantly amplifies signal, detection of low concentrations target molecules CEA. LBL approach enables precise construction multi-layered structures sensor surface, enhancing their activity optimizing performance CEA detection. These serve efficient carriers increase surface area, conductivity, structural support antibody loading, thus improving sensitivity this transducer is based decrease current response [Fe(CN)

Language: Английский

Citations

0