Worldwide risk assessment of phthalates and bisphenol A in humans: The need for updating guidelines

Environment International, Год журнала: 2023, Номер 181, С. 108294 - 108294

Опубликована: Окт. 28, 2023

Phthalates and bisphenol A (BPA) are compounds widely used as raw materials in the production of plastics, making them ubiquitous our daily lives. This results widespread human exposure health hazards. Although efforts have been conducted to evaluate risk these diverse regions around world, data scattering may mask important trends that could be useful for updating current guidelines regulations. study offers a comprehensive global assessment levels chemicals, considering dietary nondietary ingestion, evaluates associated risk. Overall, intake (EDI) values phthalates BPA reported worldwide ranged from 1.11 × 10−7 3 700 µg kg bw−1 d−1 3.00 10−5 6.56 d−1, respectively. Nevertheless, dose-additive effect has shown increase EDI up 5 100 representing high terms noncarcinogenic (HQ) carcinogenic (CR) effects. The HQ 2.25 3.66 2.74 9.72 10−2, Meanwhile, significant number studies exhibit CR benzyl butyl phthalate (BBP) di(2-ethylhexyl) (DEHP). Moreover, DEHP highest maximum mean humans numerous studies, 179-fold higher than BBP. Despite mounting evidence harmful effects chemicals at low-dose on animals humans, most regulations not updated. Thus, this article emphasizes need public policies compelling adverse exposure, it cautions against use alternative plasticizers substitutes because gaps their safety.

Язык: Английский

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Microfluidic sensors for the detection of emerging contaminants in water: A review

The Science of The Total Environment, Год журнала: 2024, Номер 929, С. 172734 - 172734

Опубликована: Апрель 24, 2024

Язык: Английский

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Degradation of microplastic in water by advanced oxidation processes

Chemosphere, Год журнала: 2024, Номер 357, С. 141939 - 141939

Опубликована: Апрель 13, 2024

Язык: Английский

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Skin protection from solar ultraviolet radiation using natural compounds: a review

Environmental Chemistry Letters, Год журнала: 2023, Номер 22(1), С. 273 - 295

Опубликована: Сен. 15, 2023

Abstract Skin exposure to solar ultraviolet radiation and pollutants causes several skin disorders, calling for protection methods such as sunscreen application. However, common contains chemicals that have displayed toxicity when exposed radiation. Therefore, alternatives approaches been recently developed, the use of natural phytochemicals active ingredients in photoprotection preparations. Here, we review with focus on physics by filters. We present sensors measuring ecosystems. discuss phototoxicity drugs, preservatives, personal care products, pollutants. Photocarcinogenesis, photoallergy, photostability, their impacts human health skin, are also reviewed. observed promising due ability absorb photon energy, thus act antioxidants.

Язык: Английский

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Synthesis of cyano and ionic dual-functional hypercrosslinked porous polymer for effective adsorption and detection of endocrine disrupting chemicals in milk matrix

Journal of Hazardous Materials, Год журнала: 2023, Номер 462, С. 132746 - 132746

Опубликована: Окт. 11, 2023

Язык: Английский

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Construction of magnetic azo-linked porous polymer for highly-efficient enrichment and separation of phenolic endocrine disruptors from environmental water and fish

Food Chemistry, Год журнала: 2024, Номер 445, С. 138698 - 138698

Опубликована: Фев. 11, 2024

Язык: Английский

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Developing a novel pyridine-based ionic porous organic polymer with functional group for highly efficient extraction of phenolic endocrine disruptors in natural water and tilapia fish

Food Chemistry, Год журнала: 2024, Номер 465, С. 142060 - 142060

Опубликована: Ноя. 14, 2024

Язык: Английский

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Bisphenol A exacerbates colorectal cancer progression through enhancing ceramide synthesis

Toxicology, Год журнала: 2025, Номер 511, С. 154054 - 154054

Опубликована: Янв. 12, 2025

Язык: Английский

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Curcumin: A Potential Detoxifier Against Chemical and Natural Toxicants

Phytotherapy Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 24, 2025

ABSTRACT The human body gets exposed to a variety of toxins intentionally or unintentionally on regular basis from sources such as air, water, food, and soil. Certain can be synthetic, while some are biological. affect the various parts by activating numerous pro‐inflammatory markers, like oxidative stresses, that tend disturb normal function organs ultimately. Nowadays, people use different types herbal treatments, viz., drinks contain spices for detoxification their bodies. One example is turmeric, most commonly available spice in kitchen used across all kinds households. Turmeric contains curcumin, which natural polyphenol. Curcumin medicinal compound with biological activities, antioxidant, antineoplastic, anti‐inflammatory, antibacterial. Hence, this review gives comprehensive insight into promising potential curcumin heavy metals, carbon tetrachloride, drugs, alcohol, acrylamide, mycotoxins, nicotine, plastics. encompasses diverse animal‐based studies portraying curcumin's role nullifying toxic effects (especially liver, kidney, testicles, brain) enhancing defensive signaling pathways, improving antioxidant enzyme levels, inhibiting markers activities so on. Furthermore, also argues over safety assessment its utilization detoxifying agent.

Язык: Английский

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Efficient Enrichment and Sensitive Determination of Endocrine Disruptors in PPCPs by Novel Magnetic Covalent Organic Framework Extraction Coupled with HPLC-MS/MS

Talanta, Год журнала: 2025, Номер 287, С. 127667 - 127667

Опубликована: Янв. 28, 2025

Язык: Английский

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