Gestational and lactational exposure to DEHP triggers ACSL4/TFR-mediated hippocampal neuronal ferroptosis via YAP activation: implication for the neurocognitive disorders in male offspring DOI

Pu Zhao,

Yang Zhao,

Yilu Ma

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138081 - 138081

Опубликована: Март 1, 2025

Язык: Английский

Microplastic contamination in some beverages marketed in türkiye: Characteristics, dietary exposure and risk assessment DOI
Burhan Başaran, Ülgen Aytan, Yasemen Şentürk

и другие.

Food and Chemical Toxicology, Год журнала: 2024, Номер 189, С. 114730 - 114730

Опубликована: Май 11, 2024

Язык: Английский

Процитировано

15

Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023 DOI Creative Commons
Ilaria Neri, Giacomo Russo, Lucia Grumetto

и другие.

Archives of Toxicology, Год журнала: 2024, Номер 98(8), С. 2441 - 2461

Опубликована: Июнь 12, 2024

In this review article, the research works covering analytical determination of bisphenol A (BPA) and its structural analogues published from 2018 to present (February 2024) were examined. The offers an overview concentration levels these xenoestrogens in food beverages, discusses concerns that may possibly pose human health scrutinises, perspective, main biomonitoring approaches are applied. This comes as a natural evolution previous covered same topic but earlier years (up 2017). As compared past, while volume literature on has not necessarily decreased, studies now much more homogeneous terms their geographical origin, i.e., Southern Europe (mainly Italy Spain). For reason, estimated daily intake European population could be calculated at time. applied, 67% groups exploited liquid chromatography (LC), with detection was prevalently (71%) afforded by mass spectrometry, over one-fourth teams using fluorescence (26%) minority (3%) detecting analytes diode array detection. One-third used gas (GC)-mass spectrometry achieving comparatively superior efficiency LC. Derivatisation performed 59% GC afford symmetrical signals enhanced sensitivity. Although contamination well below threshold set governments, routinely is encouraged because possible accumulation contaminants body interplay other xenoestrogens.

Язык: Английский

Процитировано

14

Phthalate exposure and markers of biological aging: The mediating role of inflammation and moderating role of dietary nutrient intake DOI Creative Commons
Xin Xu,

Jianheng Zheng,

Jing Li

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 281, С. 116649 - 116649

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

14

Paternal exposures to endocrine-disrupting chemicals induce intergenerational epigenetic influences on offspring: A review DOI Creative Commons
Yinan Zhang, Feng Wang,

Wenhui Sun

и другие.

Environment International, Год журнала: 2024, Номер 187, С. 108689 - 108689

Опубликована: Апрель 24, 2024

Endocrine-disrupting chemicals (EDCs) are ubiquitous in ecological environments and have become a great issue of public health concern since the 1990 s. There is deep scientific understanding toxicity EDCs. However, recent studies found that abnormal physiological functions parents caused by EDCs could be transmitted to their unexposed offspring, leading intergenerational toxicity. We questioned whether sustained epigenetic changes occur through male germline. In this review, we (1) systematically searched available research on impacts aquatic mammal organisms, including 42 articles, (2) summarized genetic effects, such as decreased offspring survival, reproductive dysfunction, metabolic disorders, behavioral abnormalities, (3) mechanisms paternal interactions, (4) propose suggestions future directions develop deeper risk

Язык: Английский

Процитировано

12

Advancing groundwater quality predictions: Machine learning challenges and solutions DOI
Juan Antonio Torres-Martínez, Jürgen Mahlknecht, Manish Kumar

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 949, С. 174973 - 174973

Опубликована: Июль 23, 2024

Язык: Английский

Процитировано

12

Microplastics in honey from Türkiye: Occurrence, characteristic, human exposure, and risk assessment DOI
Burhan Başaran, Zehra Özçi̇fçi̇, Esra Demir Kanbur

и другие.

Journal of Food Composition and Analysis, Год журнала: 2024, Номер 135, С. 106646 - 106646

Опубликована: Авг. 11, 2024

Язык: Английский

Процитировано

12

Curcumin: A Potential Detoxifier Against Chemical and Natural Toxicants DOI Open Access
Harsh Kumar, Rajni Dhalaria, Neetika Kimta

и другие.

Phytotherapy Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 24, 2025

ABSTRACT The human body gets exposed to a variety of toxins intentionally or unintentionally on regular basis from sources such as air, water, food, and soil. Certain can be synthetic, while some are biological. affect the various parts by activating numerous pro‐inflammatory markers, like oxidative stresses, that tend disturb normal function organs ultimately. Nowadays, people use different types herbal treatments, viz., drinks contain spices for detoxification their bodies. One example is turmeric, most commonly available spice in kitchen used across all kinds households. Turmeric contains curcumin, which natural polyphenol. Curcumin medicinal compound with biological activities, antioxidant, antineoplastic, anti‐inflammatory, antibacterial. Hence, this review gives comprehensive insight into promising potential curcumin heavy metals, carbon tetrachloride, drugs, alcohol, acrylamide, mycotoxins, nicotine, plastics. encompasses diverse animal‐based studies portraying curcumin's role nullifying toxic effects (especially liver, kidney, testicles, brain) enhancing defensive signaling pathways, improving antioxidant enzyme levels, inhibiting markers activities so on. Furthermore, also argues over safety assessment its utilization detoxifying agent.

Язык: Английский

Процитировано

1

A comprehensive review on exposure to toxins and health risks from plastic waste: Challenges, mitigation measures, and policy interventions DOI Creative Commons

Salia S. Sheriff,

Abdulfatah Abdu Yusuf, Oluwole Akiyode

и другие.

Waste Management Bulletin, Год журнала: 2025, Номер unknown, С. 100204 - 100204

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

1

Exploring the toxicological impact of bisphenol a exposure on psoriasis through network toxicology, machine learning, and multi-dimensional bioinformatics analysis DOI
Chun Feng, Yan Wen, Zhen Mei

и другие.

Journal of Environmental Management, Год журнала: 2025, Номер 385, С. 125708 - 125708

Опубликована: Май 10, 2025

Язык: Английский

Процитировано

1

Exposure to di-2-ethylhexyl phthalate and breast neoplasm incidence: A cohort study DOI Creative Commons

Lijuan Tang,

Yimeng Wang,

Wenting Yan

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 926, С. 171819 - 171819

Опубликована: Март 19, 2024

Phthalates are ubiquitous environmental endocrine disruptors. As the predominant phthalate, di-2-ethylhexyl phthalate (DEHP) has been considered possibly carcinogenic to humans but large-scale longitudinal evidence is needed further clarify its carcinogenicity. To examine association between DEHP exposure and incidence of breast malignant neoplasm, carcinoma in situ benign neoplasm. A total 273,295 women from UK Biobank cohort were followed up for a median 13.5 years. Disease information was collected National Health Service Cancer Registry Death Index. Baseline yearly-average level estimated each individual by linking chemical monitoring record European Environment Agency with home address participants Kriging interpolation model. Cox proportional hazard model employed estimate neoplasms. The (IQR) baseline concentration 8000.25 (interquartile range: 6657.85–11,948.83) 1819.93–11,359.55) μg/L. highest quartile associated 1.11 fold risk (95 % CI, 1.00, 1.23, p < 0.001) 1.27 neoplasm 1.05, 1.54, 0.001). exposure, positively higher (HR, 1.05; 95 1.03, 1.07, 0.001), 1.08; 1.04, 1.11, 1.13; 1.20, Stratification analyses showed no significant modification effect on DEHP-neoplasm relationship menopausal status or ethnicity suggestive younger those who underwent oral contraceptive pill therapy. In sensitivity analysis, associations remained when excluding cases diagnosed within 2 years post baseline. Real-world Because health risks DEHP, release environment should be managed.

Язык: Английский

Процитировано

9