Russian Journal of Developmental Biology, Год журнала: 2024, Номер 55(2), С. 39 - 56
Опубликована: Апрель 1, 2024
Язык: Английский
Journal of Thermal Biology, Год журнала: 2024, Номер 123, С. 103913 - 103913
Опубликована: Июль 1, 2024
Oxidative stress is thought to be one of the main causes ageing as it progressively damages cell components throughout life, eventually causing cellular failure and apoptosis. In many organisms, telomeres shorten life under effect of, amongst other factors, oxidative stress, are therefore commonly used marker biological ageing. However, hibernators, which regularly exposed acute when rewarming from torpor, unexpectedly long-lived. this review, we explore associated with hibernation its impact on telomere dynamics in different taxa, focussing hibernating rodents. We then speculate adaptive mechanisms hibernators compensate for effects may explain their increased longevity. Because winter appears high particularly rodents, periodically invest repair antioxidant defences, resulting seasonal variations lengths. This research shows how species a slow life-history strategy deal large changes unifying evolutionary physiological theories marked variation length, also draw attention using markers aging heterotherms possibly highly species.
Язык: Английский
Процитировано
2
Biogerontology, Год журнала: 2024, Номер 25(2), С. 191 - 193
Опубликована: Март 5, 2024
In this special issue we commemorate theoretical biologist Alexey Olovnikov (1936–2022), whose theory of marginotomy has laid the foundation for new field biology that studies molecular structure telomeres and its role in health, longevity aging. This contains a collection reviews research articles discuss different aspects telomere telomerase research, ranging from length dynamics wild animal populations to problems maintenance during human space flight.
Язык: Английский
Процитировано
2
Russian Journal of Developmental Biology, Год журнала: 2024, Номер 55(2), С. 39 - 56
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
0