When and How Telomeres Lengthen in Development and Cell Lines: Evolution of Olovnikov’s Telomere Theory DOI Creative Commons
Alla Kalmykova

Russian Journal of Developmental Biology, Journal Year: 2024, Volume and Issue: 55(2), P. 39 - 56

Published: April 1, 2024

Language: Английский

Telomeres in health and longevity: special issue in memory of Alexey Olovnikov DOI Creative Commons
Ivan Olovnikov

Biogerontology, Journal Year: 2024, Volume and Issue: 25(2), P. 191 - 193

Published: March 5, 2024

In this special issue we commemorate theoretical biologist Alexey Olovnikov (1936–2022), whose theory of marginotomy has laid the foundation for new field biology that studies molecular structure telomeres and its role in health, longevity aging. This contains a collection reviews research articles discuss different aspects telomere telomerase research, ranging from length dynamics wild animal populations to problems maintenance during human space flight.

Language: Английский

Citations

2
Understanding seasonal telomere length dynamics in hibernating species DOI Creative Commons
Lilian Redon, Théo Constant, Steve Smith

et al.

Journal of Thermal Biology, Journal Year: 2024, Volume and Issue: 123, P. 103913 - 103913

Published: July 1, 2024

Oxidative stress is thought to be one of the main causes ageing as it progressively damages cell components throughout life, eventually causing cellular failure and apoptosis. In many organisms, telomeres shorten life under effect of, amongst other factors, oxidative stress, are therefore commonly used marker biological ageing. However, hibernators, which regularly exposed acute when rewarming from torpor, unexpectedly long-lived. this review, we explore associated with hibernation its impact on telomere dynamics in different taxa, focussing hibernating rodents. We then speculate adaptive mechanisms hibernators compensate for effects may explain their increased longevity. Because winter appears high particularly rodents, periodically invest repair antioxidant defences, resulting seasonal variations lengths. This research shows how species a slow life-history strategy deal large changes unifying evolutionary physiological theories marked variation length, also draw attention using markers aging heterotherms possibly highly species.

Language: Английский

Citations

2
When and How Telomeres Lengthen in Development and Cell Lines: Evolution of Olovnikov’s Telomere Theory DOI Creative Commons
Alla Kalmykova

Russian Journal of Developmental Biology, Journal Year: 2024, Volume and Issue: 55(2), P. 39 - 56

Published: April 1, 2024

Language: Английский

Citations

0