Toxicity of Metal Oxides, Dyes, and Dissolved Organic Matter in Water: Implications for the Environment and Human Health

Toxics, Год журнала: 2024, Номер 12(2), С. 111 - 111

Опубликована: Янв. 28, 2024

This study delves into the critical issue of water pollution caused by presence metal oxides, synthetic dyes, and dissolved organic matter, shedding light on their potential ramifications for both environment human health. Metal ubiquitous in industrial processes consumer products, are known to leach bodies, posing a significant threat aquatic ecosystems. Additionally, extensively used various industries, can persist systems exhibit complex chemical behavior. review provides comprehensive examination toxicity associated with matter systems. We delve sources environmental fate these contaminants, highlighting prevalence natural bodies wastewater effluents. The highlights multifaceted impacts them health ecosystems, encompassing effects microbial communities, flora fauna, overall ecological balance. novelty this lies its unique presentation, focusing matter. approach aims facilitate accessibility results readers, providing streamlined clear understanding reported findings.

Язык: Английский

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Heavy metals: toxicity and human health effects

Archives of Toxicology, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 20, 2024

Abstract Heavy metals are naturally occurring components of the Earth’s crust and persistent environmental pollutants. Human exposure to heavy occurs via various pathways, including inhalation air/dust particles, ingesting contaminated water or soil, through food chain. Their bioaccumulation may lead diverse toxic effects affecting different body tissues organ systems. The toxicity depends on properties given metal, dose, route, duration (acute chronic), extent bioaccumulation. detrimental impacts human health largely linked their capacity interfere with antioxidant defense mechanisms, primarily interaction intracellular glutathione (GSH) sulfhydryl groups (R-SH) enzymes such as superoxide dismutase (SOD), catalase, peroxidase (GPx), reductase (GR), other enzyme Although arsenic (As) is believed bind directly critical thiols, alternative hydrogen peroxide production processes have also been postulated. known signaling pathways affect a variety cellular processes, cell growth, proliferation, survival, metabolism, apoptosis. For example, cadmium can BLC-2 family proteins involved in mitochondrial death overexpression antiapoptotic Bcl-2 suppression proapoptotic (BAX, BAK) thus increasing resistance cells undergo malignant transformation. Nuclear factor erythroid 2-related 2 (Nrf2) an important regulator enzymes, level oxidative stress, oxidants has shown act double-edged sword response arsenic-induced stress. Another mechanism significant threats metal (e.g., Pb) involves substitution essential calcium (Ca), copper (Cu), iron (Fe)) structurally similar (Cd) (Pb)) metal-binding sites proteins. Displaced redox (copper, iron, manganese) from natural catalyze decomposition Fenton reaction generate damaging ROS hydroxyl radicals, causing damage lipids, proteins, DNA. Conversely, some metals, cadmium, suppress synthesis nitric oxide radical (NO · ), manifested by altered vasorelaxation and, consequently, blood pressure regulation. Pb-induced stress be indirectly responsible for depletion due its (O ·− resulting formation potent biological oxidant, peroxynitrite (ONOO − ). This review comprehensively discusses mechanisms effects. Aluminum (Al), (Cd), (As), mercury (Hg), (Pb), chromium (Cr) roles development gastrointestinal, pulmonary, kidney, reproductive, neurodegenerative (Alzheimer’s Parkinson’s diseases), cardiovascular, cancer (e.g. renal, lung, skin, stomach) diseases discussed. A short account devoted detoxification chelation use ethylenediaminetetraacetic acid ( EDTA), dimercaprol (BAL), 2,3-dimercaptosuccinic (DMSA), 2,3-dimercapto-1-propane sulfonic (DMPS), penicillamine chelators.

Язык: Английский

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Bioaccumulation of metals in muscle tissues of economically important fish species from black sea Lagoon lakes in Türkiye: Consumer health risk and nutritional value assessment

Microchemical Journal, Год журнала: 2024, Номер 205, С. 111337 - 111337

Опубликована: Июль 31, 2024

Язык: Английский

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Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East

Nutrients, Год журнала: 2022, Номер 14(10), С. 2136 - 2136

Опубликована: Май 20, 2022

Dietary arsenic (As) contamination is a major public health issue. In the Middle East, food supply relies primarily on import of commodities. Among different age groups main source As exposure grains and grain-based products, particularly rice rice-based dietary products. Rice products are rich core macronutrients act as chief energy across world. The rate consumption ranges from 250 to 650 g per day person in South East Asian countries. carbohydrates through one leading causes human exposure. Gulf population consumes ready-to-eat cereals large proportion their meals. Exposure leads an increased risk non-communicable diseases such dysbiosis, obesity, metabolic syndrome, diabetes, chronic kidney disease, heart cancer, maternal fetal complications. impact arsenic-containing items outcomes among groups. countries, neurological deficit disorder (NDD) autism spectrum (ASD) cases alarming issues. Arsenic might be causative factor that should assessed by screening regulatory bodies rechecking limits all Our goals for this review outline distribution various foods water summarize complications linked with toxicity along identified modifiers add heterogeneity biological responses suggest improvements multi-disciplinary interventions minimize global influence arsenic. development validation diverse analytical techniques evaluate toxic levels contaminants our need hour. Furthermore, standard parameters guidelines As-containing developed implemented.

Язык: Английский

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A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Frontiers in Veterinary Science, Год журнала: 2023, Номер 10

Опубликована: Март 29, 2023

Toxicity with heavy metals has proven to be a significant hazard several health problems linked it. Heavy bioaccumulate in living organisms, pollute the food chain, and possibly threaten of animals. Many industries, fertilizers, traffic, automobile, paint, groundwater, animal feed are sources contamination metals. Few metals, such as aluminum (Al), may eliminated by elimination processes, but other like lead (Pb), arsenic (As), cadmium (Ca) accumulate body leading chronic toxicity Even if these have no biological purpose, their toxic effects still present some form that is damaging its appropriate functioning. Cadmium (Cd) Pb negative impacts on number physiological biochemical processes when exposed sub-lethal doses. The nephrotoxic Pb, As, Cd well known, high amounts naturally occurring environmental occupational populations exposures an adverse relationship between kidney damage metal exposure. Metal determined absorbed dosage, route exposure, duration whether acute or chronic. This can numerous disorders also result excessive due oxidative stress generated free radical production. concentration decreased through various procedures including bioremediation, pyrolysis, phytoremediation, rhizofiltration, biochar, thermal process. review discusses few mechanisms, cattle special emphasis kidneys.

Язык: Английский

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Copper, Iron, Cadmium, and Arsenic, All Generated in the Universe: Elucidating Their Environmental Impact Risk on Human Health Including Clinical Liver Injury

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(12), С. 6662 - 6662

Опубликована: Июнь 17, 2024

Humans are continuously exposed to various heavy metals including copper, iron, cadmium, and arsenic, which were specifically selected for the current analysis because they among most frequently encountered environmental mankind industrial pollutants potentially causing human health hazards liver injury. So far, these issues poorly assessed remained a matter of debate, also due inconsistent results. The aim actual report is thoroughly analyze positive as well negative effects four on health. Copper iron correctly viewed pollutant elements essential maintaining part important enzymes metabolic pathways. Healthy individuals prepared through genetically based mechanisms maintain cellular copper homeostasis, thereby circumventing or reducing hazardous organ injury excessive amounts entering body. In few humans with gene aberration, however, may develop excessively accumulated can lead Wilson disease substantial deposition hemochromatosis. At molecular level, toxicities some traced back Haber Weiss Fenton reactions involving reactive oxygen species formed in course oxidative stress. On other hand, homeostasis cadmium arsenic cannot be provided, their life-long organs. Consequently, represent leading higher disability-adjusted life years increased mortality rates cancer non-cancer diseases. For unknown reasons, rarely observed. sum, good except those hemochromatosis at risk radical formation, while lack any beneficial but rather focus disability potential cancer. Primary efforts should emission metals.

Язык: Английский

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Microbial mediated remediation of heavy metals toxicity: mechanisms and future prospects

Frontiers in Plant Science, Год журнала: 2024, Номер 15

Опубликована: Июль 19, 2024

Heavy metal pollution has become a serious concern across the globe due to their persistent nature, higher toxicity, and recalcitrance. These toxic metals threaten stability of environment health all living beings. also enter human food chain by eating contaminated foods cause effects on health. Thus, remediation HMs polluted soils is mandatory it needs be addressed at priority. The use microbes considered as promising approach combat adverse impacts HMs. Microbes aided in restoration deteriorated environments natural condition, with long-term environmental effects. Microbial prevents leaching mobilization they make extraction simple. Therefore, this context recent technological advancement allowed bioremediation an imperative remediate soils. different mechanisms including bio-sorption, bioaccumulation, bioleaching, bio-transformation, bio-volatilization bio-mineralization mitigate keeping view here review explores role bacteria, fungi algae This discusses various approaches that can used improve efficiency It highlights research gaps must solved future study programs efficency.

Язык: Английский

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Evaluating the efficiency of zeolitic imidazolate framework-67(ZIF-67) in elimination of arsenate from aqueous media by response surface methodology

Results in Chemistry, Год журнала: 2024, Номер unknown, С. 101811 - 101811

Опубликована: Сен. 1, 2024

Язык: Английский

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Exploring microgel adsorption: synthesis, classification, and pollutant removal dynamics

RSC Advances, Год журнала: 2024, Номер 14(14), С. 9445 - 9471

Опубликована: Янв. 1, 2024

Microgels have gained significant importance for the removal of pollutants owing to their stimulus-responsive behavior, high stability, and reusable capacity. However, despite these advantages, several hurdles need be overcome fully maximize potential as effective adsorbents eradicating various contaminants from environment, such metallic cations, organic compounds, anions, harmful gases, dyes. Therefore, a critical review on adsorption by microgels is needed. In this regard, presents latest developments in adsorptive properties microgels. The synthetic methods, architectural structures, behavior are explained detail. addition, explores factors that directly influence microgels, pH, feed composition, content pollutants, comonomers, agitation time, temperature, microgel dose, nature both adsorbates (pollutants) (microgels), medium, ionic strength. Various isotherms also explored together with kinetic aspects process provide comprehensive understanding.

Язык: Английский

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Sustainable soil management under drought stress through biochar application: Immobilizing arsenic, ameliorating soil quality, and augmenting plant growth

Environmental Research, Год журнала: 2024, Номер 259, С. 119531 - 119531

Опубликована: Июль 1, 2024

Язык: Английский

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