Toxics,
Год журнала:
2025,
Номер
13(3), С. 224 - 224
Опубликована: Март 19, 2025
Micro(nano)plastics
(MNPs)
pose
a
significant
threat
to
both
ecological
environments
and
human
health.
This
review
systematically
examines
the
developmental
toxicity
of
MNPs
in
mammals,
with
particular
focus
on
impact
maternal
paternal
exposure
offspring.
Evidence
indicates
that
can
cross
placental
barriers,
inducing
abnormal
development
embryos,
fetuses,
placentas.
disruption
leads
range
adverse
outcomes,
including
neurodevelopmental
abnormalities,
behavioral
disorders,
reproductive
system
damage,
etc.,
Through
comprehensive
analysis
existing
literature,
this
aims
provide
foundation
for
future
research
highlight
urgent
need
action
mitigate
detrimental
effects
health
ecosystem
integrity.
Abstract
Since
the
1960s,
more
than
350,000
new
chemicals
have
been
introduced
into
lives
of
humans
and
domestic
animals.
Many
them
become
part
modern
life
some
are
affecting
nature
as
pollutants.
Yet,
our
comprehension
their
potential
health
risks
for
both
animals
remains
partial.
The
“epithelial
barrier
theory”
suggests
that
genetic
predisposition
exposure
to
diverse
factors
damaging
epithelial
barriers
contribute
emergence
allergic
autoimmune
conditions.
Impaired
barriers,
microbial
dysbiosis,
tissue
inflammation
observed
in
a
high
number
mucosal
inflammatory,
neuropsychiatric
diseases,
many
which
showed
increased
prevalence
last
decades.
Pets,
especially
cats
dogs,
share
living
spaces
with
exposed
household
cleaners,
personal
care
products,
air
pollutants,
microplastics.
utilisation
cosmetic
products
food
additives
pets
is
on
rise,
unfortunately,
accompanied
by
less
rigorous
safety
regulations
those
governing
human
products.
In
this
review,
we
explore
implications
disruptions
well‐being
companion
animals,
drawing
comparisons
humans,
endeavour
elucidate
spectrum
diseases
afflict
them.
addition,
future
research
areas
interconnectedness
human,
animal,
environmental
highlighted
line
“One
Health”
concept.
Environmental Toxicology,
Год журнала:
2024,
Номер
39(11), С. 4899 - 4926
Опубликована: Июнь 25, 2024
ABSTRACT
The
interaction
between
particles
and
proteins
is
a
key
factor
determining
the
toxicity
responses
of
particles.
Therefore,
this
study
aimed
to
examine
emerging
pollutant
polyethylene
terephthalate
micro/nanoplastics
from
water
bottles
with
bovine
serum
albumin.
physicochemical
characteristics
were
investigated
using
nuclear
magnetic
resonance,
x‐ray
diffraction,
Fourier
transform
infrared,
dynamic
light
scattering,
energy
dispersive
spectroscopy
after
exposure
various
concentrations
durations
protein.
Furthermore,
impact
protein‐treated
on
biological
activities
was
examined
mitochondrial
activity
membrane
integrity
A549
cells
biofilm
production
Staphylococcus
aureus
.
structural
revealed
an
For
instance,
assignment
protein‐related
new
proton
signals
(e.g.,
CH
2
,
methylene
protons
CH
O),
changes
in
available
s
3
),
crystallinity,
functional
groups,
elemental
ratios,
zeta
potentials
(−11.3
±
1.3
−12.4
1.7
25.5
2.3
mV),
particle
size
(395
76
496
60
866
82
nm)
significantly
observed
protein
treatment.
In
addition,
loading
(0.012–0.027
mM)
releasing
(0.008–0.013
also
showed
similar
characteristics.
Moreover,
cell‐based
changed
regarding
surface
efficiencies
example,
insignificant
(2%–10%)
significant
(12%–28%)
increased
compared
control,
reductions
bacterial
(5%–40%)
many
cases
specifically
at
low
dose
all
treatment
stages
(13%–46%
reduction)
observed.
Biomedicines,
Год журнала:
2024,
Номер
12(8), С. 1714 - 1714
Опубликована: Авг. 1, 2024
Plastic-based
products
are
ubiquitous
due
to
their
tremendous
utility
in
our
daily
lives.
Nanoplastic
(NP)
and
microplastic
(MP)
pollution
has
become
a
severe
threat
the
planet
is
growing
concern.
It
been
widely
reported
that
polystyrene
(PS)
MPs
severely
toxic
male
reproduction
system,
with
effects
including
decreased
sperm
parameters,
impaired
spermatogenesis,
damaged
testicular
structures.
However,
molecular
mechanisms
for
spermatogenesis
remain
poorly
understood.
Toxics,
Год журнала:
2025,
Номер
13(3), С. 224 - 224
Опубликована: Март 19, 2025
Micro(nano)plastics
(MNPs)
pose
a
significant
threat
to
both
ecological
environments
and
human
health.
This
review
systematically
examines
the
developmental
toxicity
of
MNPs
in
mammals,
with
particular
focus
on
impact
maternal
paternal
exposure
offspring.
Evidence
indicates
that
can
cross
placental
barriers,
inducing
abnormal
development
embryos,
fetuses,
placentas.
disruption
leads
range
adverse
outcomes,
including
neurodevelopmental
abnormalities,
behavioral
disorders,
reproductive
system
damage,
etc.,
Through
comprehensive
analysis
existing
literature,
this
aims
provide
foundation
for
future
research
highlight
urgent
need
action
mitigate
detrimental
effects
health
ecosystem
integrity.
