ACS Applied Nano Materials,
Год журнала:
2023,
Номер
7(1), С. 1388 - 1401
Опубликована: Дек. 18, 2023
Hybrid
nanomaterials
with
distinct
properties
and
morphologies
when
clubbed
within
a
sensor
matrix
can
generate
synergistic
effect
on
molecular
sensing.
In
this
work,
creation
of
such
nanohybrid
platform
has
been
attempted
for
rapid
detection
hydrogen
peroxide
(H2O2),
which
tremendous
role
in
area
medical
diagnostics.
Conventionally,
the
peroxidase
(POD)
enzyme
catalyzes
H2O2;
however,
it
is
prone
to
inherent
chemical
thermal
instabilities
reducing
overall
stability
shelf
life
probe.
A
possible
solution
problem
work
where
nonenzymatic
mimic
probe
comprising
gold
nanodendrites
(AuND),
nickel
metal
organic
framework
(Ni-MOF),
hydrazine
synergistically
deployed
H2O2.
The
developed
rigorously
characterized
through
various
characterization
techniques,
including
scanning
microscopy
(SPM),
electron
(SEM),
energy
dispersive
X-ray
analysis
(EDX-mapping),
Fourier
transform
infrared
spectroscopy
(FTIR),
diffraction
(XRD),
photoelectron
(XPS),
cyclic
voltammetry
(CV),
electrochemical
impedance
(EIS).
demonstrated
impressive
analytical
performance,
possessing
linear
dynamic
range
(LDR)
between
1
×
10–8
M
10–15
limit
(LOD)
0.34
(±0.05)
M.
probe's
average
response
time
changing
H2O2
concentrations
was
5.02
±
0.42
s,
making
an
agile
sensing
detection.
displayed
minimal
toward
interferants
as
superoxide
radicals,
ascorbic
acid,
cysteine,
glucose,
alanine,
citric
usually
coexist
real
sample
matrix.
order
investigate
real-life
applicability
probe,
involving
synthetic
serum
adopted,
yielded
current
recovery
90.20
94.14%.
fabrication
on-chip
synthesis
procedure
are
facile,
robust
efficient
free
radicals
clinical
settings.
Reaction Chemistry & Engineering,
Год журнала:
2022,
Номер
8(2), С. 278 - 310
Опубликована: Дек. 9, 2022
Metal
organic
frameworks
(MOFs)
are
an
emerging
class
of
porous
inorganic–organic
high
profile
hybrid
compounds
that
have
attracted
much
attention
in
recent
times
due
to
their
stunning
properties.
Chemosensors,
Год журнала:
2023,
Номер
11(8), С. 429 - 429
Опубликована: Авг. 2, 2023
Metal–organic
frameworks
(MOFs),
constructed
by
coordination
between
metal-containing
nodes
and
organic
linkers,
are
widely
used
in
various
fields
due
to
the
advantages
of
tunable
pores,
diverse
functional
sites,
stable
structure,
multi-functionality.
It
should
be
noted
that
MOF-based
materials
play
a
major
role
glucose
detection,
serving
as
signal
transducer
or
substrate
for
embedding
nanoparticles/enzymes.
Diabetes
is
one
most
common
fast-growing
diseases
worldwide,
whose
main
clinical
manifestation
high
blood
sugar
levels.
Therefore,
accurate,
sensitive,
point-of-care
detection
necessary.
This
review
orderly
introduces
general
synthetic
strategies
(pristine
MOF,
nanoparticles,
enzymes-modified
MOF
MOF-derived
materials)
methods
(electrochemical
optical
methods)
detection.
Then,
refers
novel
devices
(flexible
wearable
microfluidic
chips),
which
enable
non-invasive
continuous
monitoring
low-cost
microscale
On
basis
describing
development
sensors
based
on
past
five
years,
presents
merits,
demerits,
possible
improvements
methods.
ACS Catalysis,
Год журнала:
2023,
Номер
13(5), С. 3224 - 3241
Опубликована: Фев. 20, 2023
In
this
work,
MOF-derived
Ni@C
catalysts
with
rich
defects
were
synthesized
using
a
facile
thermally
decarboxylation-induced
defect
strategy
for
nitrocyclohexane
(NCH)
hydrogenation.
It
was
found
that
the
strong
metal–support
interaction
(SMSI)
between
defect-rich
carbon
and
Ni
promotes
dispersion
of
nanoparticles,
reduces
particle
size,
affects
surface
charge
state
to
form
electron-deficient
Ni,
thus
exhibiting
outstanding
catalytic
activity.
Additionally,
in
situ
diffuse
reflectance
infrared
Fourier
transform
spectroscopy
(in
DRIFTS)
illustrates
transformation
path
nitrosocyclohexane
(N-NCH)
is
critical
obtaining
high
selectivity
cyclohexanone
oxime
(CHO).
Furthermore,
density
functional
theory
(DFT)
calculations
confirm
SMSI
leads
formation
lower
d-band
center,
which
can
weaken
adsorption
N-NCH
CHO,
enhance
N-cyclohexylhydroxylamine
(N-CHH)
cyclohexylamine
(CHA),
reduce
reaction
energy
increase
CHA,
showing
highest
CHO.
Under
optimum
conditions,
[email protected]
gives
97.2%
CHO
at
95.2%
NCH
conversion.
Journal of Nanobiotechnology,
Год журнала:
2023,
Номер
21(1)
Опубликована: Апрель 26, 2023
Abstract
It
is
essential
to
develop
ultrasensitive
biosensors
for
cancer
detection
and
treatment
monitoring.
In
the
development
of
sensing
platforms,
metal-organic
frameworks
(MOFs)
have
received
considerable
attention
as
potential
porous
crystalline
nanostructures.
Core-shell
MOF
nanoparticles
(NPs)
shown
different
diversities,
complexities,
biological
functionalities,
well
significant
electrochemical
(EC)
properties
bio-affinity
aptamers.
As
a
result,
developed
core-shell
MOF-based
aptasensors
serve
highly
sensitive
platforms
biomarkers
with
an
extremely
low
limit
(LOD).
This
paper
aimed
provide
overview
strategies
improving
selectivity,
sensitivity,
signal
strength
Then,
aptamers
aptamers-modified
MOFs
were
reviewed
address
their
functionalization
application
in
biosensing
platforms.
Additionally,
MOF-assisted
EC
several
tumor
antigens
such
prostate-specific
antigen
(PSA),
carbohydrate
15-3
(CA15-3),
carcinoembryonic
(CEA),
human
epidermal
growth
factor
receptor-2
(HER2),
125
(CA-125),
cytokeratin
19
fragment
(CYFRA21-1),
other
markers
discussed.
conclusion,
present
article
reviews
advancement
toward
specific
through
MOFs-based
aptasensors.
