Preparation, characterization, and anticancer evaluation of polydatin conjugated with zinc MOF and encapsulated by liponiosomes as a potential nanotool-induce apoptosis

Journal of Molecular Structure, Год журнала: 2024, Номер 1315, С. 138982 - 138982

Опубликована: Июнь 12, 2024

Язык: Английский

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Engineered Conductive Metal–organic Frameworks for Electrochemical Detection of Urinary Biomarkers

Small, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

Abstract The increasing prevalence of health concerns has sparked a demand for advanced monitoring tools, which is significant challenge researchers. Analysis biofluid samples and biomarker vital comprehensive assessment. In this context, metal–organic frameworks (MOFs) have emerged as one the leading materials developing cutting‐edge artificial sensors. These unique MOFs been developed from metallic organic linkers consist tunable pores dynamic surface areas, attracting various guest molecules to participate in electrochemical devices. This study gateway world where MOF designs transcend mere inventions, morphing into electric marvels that revolutionize urine sample monitoring. From inception design fabrication sensors tailored applications, prides itself on elucidating factors affecting MOF‐based electrical devices Moreover, focus placed conductivity, electrode properties, recent state‐of‐the‐art analysis, highlighting pivotal role biomarkers play honing resilience performance Finally, specific used analysis. It will attract researchers develop new portable tools by analyzing samples.

Язык: Английский

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Anticancer effects of silymarin-loaded ACA-HA/sulfonamide IR-MOF nanoplatform in CT-26 xenograft model

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142651 - 142651

Опубликована: Март 1, 2025

Язык: Английский

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Iron‐MOFs for Biomedical Applications

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Окт. 10, 2024

Over the past two decades, iron-based metal-organic frameworks (Fe-MOFs) have attracted significant research interest in biomedicine due to their low toxicity, tunable degradability, substantial drug loading capacity, versatile structures, and multimodal functionalities. Despite great potential, transition of Fe-MOFs-based composites from laboratory clinical products remains challenging. This review evaluates key properties that distinguish Fe-MOFs other MOFs highlights recent advances synthesis routes, surface engineering, shaping technologies. In particular, it focuses on applications biosensing, antimicrobial, anticancer therapies. addition, emphasizes need develop scalable, environmentally friendly, cost-effective production methods for additional meet specific requirements various biomedical applications. ability combine therapies, hurdles still remain, including a deeper understanding therapeutic mechanisms potential risks resistance overdose. Systematically addressing these challenges could significantly enhance prospects potentially facilitate integration into mainstream practice.

Язык: Английский

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Rational design of metal organic frameworks as the carriers for improving the efficiency of cancer drug delivery

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 102, С. 106378 - 106378

Опубликована: Ноя. 5, 2024

Язык: Английский

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