The association between adaptability and the symptoms of depression and anxiety in early adolescents: a network analysis in a longitudinal design
BMC Psychiatry,
Год журнала:
2025,
Номер
25(1)
Опубликована: Фев. 12, 2025
Abstract
Background
The
co-occurrence
of
depression
and
anxiety
is
relatively
more
common
among
adolescents.
Emerging
evidence
suggests
that
adaptability
might
affect
this
phenomenon.
Network
analysis
can
provide
insight
into
the
dynamics
between
symptoms
mental
disorders.
Therefore,
we
used
network
1)
to
explore
symptom
networks
2)
investigate
association
based
on
a
longitudinal
design.
Methods
833
Chinese
adolescents
(449
males
384
female)
were
recruited,
with
adaptability,
depressive
measured
at
T1,
426
them
followed
up
one
year
later
T2.
Symptom
constructed
for
all
participants
two
groups
their
scores
T1.
Furthermore,
mediation
was
performed
examine
relationship
bridge
both
timepoints.
Results
Irritable
Guilty
showed
highest
expected
value
T1
(
p
<
0.05).
high
group’s
(HGN)
less
connected
than
low
(LGN)
0.001).
(T1)
(T2)
sequential
mediators
0.001)
(T2).
Conclusions
These
findings
suggest
dynamics,
underscoring
its
importance
occurrence
being
may
indicate
interventions
target
in
comorbid
anxiety.
Язык: Английский
The risk factors for the comorbidity of depression and self-injury in adolescents: a machine learning study
European Child & Adolescent Psychiatry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Язык: Английский
Which intervenes first? The comorbidity of sleep disturbances and anxiety symptoms among adolescents: A cross-sectional and longitudinal network analyses
Journal of Affective Disorders,
Год журнала:
2025,
Номер
378, С. 329 - 339
Опубликована: Март 4, 2025
Язык: Английский
Association between Childhood Hunger and Depression or Anxiety in Later Life: Insights from Two Case-Control Studies
Psychiatry Research,
Год журнала:
2025,
Номер
unknown, С. 116475 - 116475
Опубликована: Март 1, 2025
Язык: Английский
Why We Cannot Stop Watching: Tension and Subjective Anxious Affect as Central Emotional Predictors of Short-Form Video Addiction
International Journal of Mental Health and Addiction,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 22, 2025
Язык: Английский
Network pharmacology- and molecular docking-based investigation on the mechanism of action of Si-ni San in the treatment of depression combined with anxiety and experimental verification in adolescent rats
Frontiers in Psychiatry,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 23, 2024
Background
The
incidence
rate
of
adolescent
depression
and
anxiety
has
been
increasing
since
the
outbreak
COVID-19,
which
there
are
no
effective
therapeutic
drugs
available.
Si-ni
San
is
commonly
used
in
traditional
Chinese
medicine
for
treatment
depression-like
as
well
anxiety-like
behavior,
but
its
mechanism
treating
combined
with
during
adolescence
not
yet
clear.
Methods
Network
pharmacology
was
to
explore
potential
drug
molecules
related
targets,
molecular
docking
dynamics
(MD)
simulation
were
evaluate
interaction
between
a
model
rats
following
behavioral
tests
biology
verify
results
from
network
docking.
Results
As
result,
256
active
ingredients
1128
targets
screened
out.
Among
them,
quercetin,
Luteolin,
kaempferol,
7-Methoxy-2-methyl
isoflavone,
formononetin
showed
be
most
ingredients;
while
STAT3,
IL6,
TNF,
AKT1,
TP53,
IL1B,
MAPK3,
VEGFA,
CASP3,
MMP9
targets.
AGE-RAGE
signaling
pathway
diabetic
complications,
IL-17
pathway,
HIF-1
PI3K-Akt
TNF
involved
anti-inflammation
processes,
probable
pathways
regulated
by
San.
Molecular
MD
compounds
inflammation-associated
revealed
good
binding
abilities
nobiletin
PTGS2
PPARγ.
In
experiment
rats,
markedly
suppressed
early
maternal
separation
(MS)
chronic
unpredictable
mild
stress
(CUMS)-induced
anxiety.
qPCR
further
indicated
that
oxidative
inflammatory
response.
Conclusion
This
study
demonstrates
anxiety-
behavior
induced
MS
CUMS
can
ameliorated
improved
inflammation
hippocampus
via
targeting
Nrf2
helping
reveal
Язык: Английский
The longitudinal relationships between problematic smartphone use and anxiety symptoms among Chinese college students: A cross-lagged panel network analysis
Addictive Behaviors,
Год журнала:
2024,
Номер
160, С. 108170 - 108170
Опубликована: Сен. 19, 2024
Язык: Английский
Effects of pain, hospitalization, and medication on depressive symptom in Syrian patients with chronic diseases
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Сен. 5, 2024
Язык: Английский
Longitudinal Associations Between Anxiety and Depressive Symptoms in Adolescence, Early Adulthood, and Old Age: Cross‐Lagged Panel Network Analyses
Depression and Anxiety,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Background:
Depression
and
anxiety
are
among
the
most
prevalent
psychiatric
disorders
worldwide,
affecting
individuals
of
all
ages.
The
co-occurrence
these
often
exacerbates
their
negative
health
impacts,
underscoring
necessity
understanding
comorbid
mechanisms.
Methods:
This
study
employed
cross-lagged
panel
networks
(CLPNs)
to
explore
longitudinal
associations
between
depression
symptoms
across
three
age
groups
compare
respective
symptom
networks.
CLPNs
were
constructed
through
cross-temporal
different
symptoms,
reflecting
both
pattern
interaction
significance
specific
in
comorbidity.
sample
consisted
1258
adolescents
(aged
13-19
years,
M
=
15.98),
1118
college
students
17-24
19.94),
548
older
adults
60-101
85.19)
from
China.
assessed
using
subscales
Depression,
Anxiety,
Stress
Scale
Short
Version
(DASS-21)
at
two
time
points
over
a
6-month
period
during
2020-2021.
Results:
findings
revealed
that
prevalence
adolescents,
students,
was
25.9%/46.6%,
53.7%/61.5%,
7.2%/22.5%,
respectively.
network
structure
varied
groups:
exhibiting
tight
interconnection
while
showed
stronger
small-world
characteristics.
A
key
finding
central
role
irrational
fear.
In
addition,
somatic
frequently
emerged
as
outcomes
other
psychological
symptoms.
Conclusion:
more
pronounced
compared
adults.
Comparisons
overall
provide
insights
into
lifelong
trajectories
centrality
fears
somatization
is
emphasized.
These
results
offer
guidance
for
targeted
clinical
interventions.
Язык: Английский