Longitudinal Associations Between Anxiety and Depressive Symptoms in Adolescence, Early Adulthood, and Old Age: Cross‐Lagged Panel Network Analyses DOI Creative Commons
Shoushi Wang, Zh Yeng Chong, Chunyang Zhang

et al.

Depression and Anxiety, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Background: Depression and anxiety are among the most prevalent psychiatric disorders worldwide, affecting individuals of all ages. The co-occurrence these often exacerbates their negative health impacts, underscoring necessity understanding comorbid mechanisms. Methods: This study employed cross-lagged panel networks (CLPNs) to explore longitudinal associations between depression symptoms across three age groups compare respective symptom networks. CLPNs were constructed through cross-temporal different symptoms, reflecting both pattern interaction significance specific in comorbidity. sample consisted 1258 adolescents (aged 13-19 years, M = 15.98), 1118 college students 17-24 19.94), 548 older adults 60-101 85.19) from China. assessed using subscales Depression, Anxiety, Stress Scale Short Version (DASS-21) at two time points over a 6-month period during 2020-2021. Results: findings revealed that prevalence adolescents, students, was 25.9%/46.6%, 53.7%/61.5%, 7.2%/22.5%, respectively. network structure varied groups: exhibiting tight interconnection while showed stronger small-world characteristics. A key finding central role irrational fear. In addition, somatic frequently emerged as outcomes other psychological symptoms. Conclusion: more pronounced compared adults. Comparisons overall provide insights into lifelong trajectories centrality fears somatization is emphasized. These results offer guidance for targeted clinical interventions.

Language: Английский

The association between adaptability and the symptoms of depression and anxiety in early adolescents: a network analysis in a longitudinal design DOI Creative Commons
Guangming Lu, Liang Zhu, Ren Huang

et al.

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 12, 2025

Abstract Background The co-occurrence of depression and anxiety is relatively more common among adolescents. Emerging evidence suggests that adaptability might affect this phenomenon. Network analysis can provide insight into the dynamics between symptoms mental disorders. Therefore, we used network 1) to explore symptom networks 2) investigate association based on a longitudinal design. Methods 833 Chinese adolescents (449 males 384 female) were recruited, with adaptability, depressive measured at T1, 426 them followed up one year later T2. Symptom constructed for all participants two groups their scores T1. Furthermore, mediation was performed examine relationship bridge both timepoints. Results Irritable Guilty showed highest expected value T1 ( p < 0.05). high group’s (HGN) less connected than low (LGN) 0.001). (T1) (T2) sequential mediators 0.001) (T2). Conclusions These findings suggest dynamics, underscoring its importance occurrence being may indicate interventions target in comorbid anxiety.

Language: Английский

Citations

0
The risk factors for the comorbidity of depression and self-injury in adolescents: a machine learning study DOI

Yuancheng Huang,

Yanli Hou, Caina Li

et al.

European Child & Adolescent Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Language: Английский

Citations

0
Which intervenes first? The comorbidity of sleep disturbances and anxiety symptoms among adolescents: A cross-sectional and longitudinal network analyses DOI
Dan Chen, Haoxian Ye,

Luowei Bu

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 378, P. 329 - 339

Published: March 4, 2025

Language: Английский

Citations

0
Association between Childhood Hunger and Depression or Anxiety in Later Life: Insights from Two Case-Control Studies DOI Creative Commons
Xiaoxiao Wang,

Xinhao Hu,

Fangyi Chen

et al.

Psychiatry Research, Journal Year: 2025, Volume and Issue: unknown, P. 116475 - 116475

Published: March 1, 2025

Language: Английский

Citations

0
Why We Cannot Stop Watching: Tension and Subjective Anxious Affect as Central Emotional Predictors of Short-Form Video Addiction DOI
Shuang Li, Tong Zhao, Ningning Feng

et al.

International Journal of Mental Health and Addiction, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

Language: Английский

Citations

0
Network pharmacology- and molecular docking-based investigation on the mechanism of action of Si-ni San in the treatment of depression combined with anxiety and experimental verification in adolescent rats DOI Creative Commons
Zhiping Li,

Shimin Liang,

Xulan Cui

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 23, 2024

Background The incidence rate of adolescent depression and anxiety has been increasing since the outbreak COVID-19, which there are no effective therapeutic drugs available. Si-ni San is commonly used in traditional Chinese medicine for treatment depression-like as well anxiety-like behavior, but its mechanism treating combined with during adolescence not yet clear. Methods Network pharmacology was to explore potential drug molecules related targets, molecular docking dynamics (MD) simulation were evaluate interaction between a model rats following behavioral tests biology verify results from network docking. Results As result, 256 active ingredients 1128 targets screened out. Among them, quercetin, Luteolin, kaempferol, 7-Methoxy-2-methyl isoflavone, formononetin showed be most ingredients; while STAT3, IL6, TNF, AKT1, TP53, IL1B, MAPK3, VEGFA, CASP3, MMP9 targets. AGE-RAGE signaling pathway diabetic complications, IL-17 pathway, HIF-1 PI3K-Akt TNF involved anti-inflammation processes, probable pathways regulated by San. Molecular MD compounds inflammation-associated revealed good binding abilities nobiletin PTGS2 PPARγ. In experiment rats, markedly suppressed early maternal separation (MS) chronic unpredictable mild stress (CUMS)-induced anxiety. qPCR further indicated that oxidative inflammatory response. Conclusion This study demonstrates anxiety- behavior induced MS CUMS can ameliorated improved inflammation hippocampus via targeting Nrf2 helping reveal

Language: Английский

Citations

2
The longitudinal relationships between problematic smartphone use and anxiety symptoms among Chinese college students: A cross-lagged panel network analysis DOI
Yuhao Wang,

Yunjiao Luo,

Na Yan

et al.

Addictive Behaviors, Journal Year: 2024, Volume and Issue: 160, P. 108170 - 108170

Published: Sept. 19, 2024

Language: Английский

Citations

2
Effects of pain, hospitalization, and medication on depressive symptom in Syrian patients with chronic diseases DOI Creative Commons
Jamal Ataya, M.F. Hamdi,

Rawan Daboul

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Sept. 5, 2024

Language: Английский

Citations

0
Longitudinal Associations Between Anxiety and Depressive Symptoms in Adolescence, Early Adulthood, and Old Age: Cross‐Lagged Panel Network Analyses DOI Creative Commons
Shoushi Wang, Zh Yeng Chong, Chunyang Zhang

et al.

Depression and Anxiety, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Background: Depression and anxiety are among the most prevalent psychiatric disorders worldwide, affecting individuals of all ages. The co-occurrence these often exacerbates their negative health impacts, underscoring necessity understanding comorbid mechanisms. Methods: This study employed cross-lagged panel networks (CLPNs) to explore longitudinal associations between depression symptoms across three age groups compare respective symptom networks. CLPNs were constructed through cross-temporal different symptoms, reflecting both pattern interaction significance specific in comorbidity. sample consisted 1258 adolescents (aged 13-19 years, M = 15.98), 1118 college students 17-24 19.94), 548 older adults 60-101 85.19) from China. assessed using subscales Depression, Anxiety, Stress Scale Short Version (DASS-21) at two time points over a 6-month period during 2020-2021. Results: findings revealed that prevalence adolescents, students, was 25.9%/46.6%, 53.7%/61.5%, 7.2%/22.5%, respectively. network structure varied groups: exhibiting tight interconnection while showed stronger small-world characteristics. A key finding central role irrational fear. In addition, somatic frequently emerged as outcomes other psychological symptoms. Conclusion: more pronounced compared adults. Comparisons overall provide insights into lifelong trajectories centrality fears somatization is emphasized. These results offer guidance for targeted clinical interventions.

Language: Английский

Citations

0