Fabrication and characterization of an asymmetric bilayer wound dressing for healing acceleration of full thickness wounds DOI
Farah E. Ismaeel,

Huda Raad Kareem,

Mohamed Farid Abbas

и другие.

International Journal of Pharmaceutics, Год журнала: 2025, Номер unknown, С. 125638 - 125638

Опубликована: Апрель 1, 2025

Язык: Английский

Adjusting Morphology, Structure, and Mechanical Properties of Electrospun High‐Molecular‐Weight Poly(l‐Lactic‐Acid) Nanofibrous Yarns Through Hot Stretching Treatment DOI Open Access

Xiaoyu Liu,

Jiayi Jiang, Hailei Liu

и другие.

Macromolecular Bioscience, Год журнала: 2025, Номер unknown

Опубликована: Фев. 22, 2025

Abstract An integrated strategy that combines innovative electrospinning technique with traditional hot‐stretching post‐treatment is designed and implemented to generate high‐molecular‐weight poly(l‐lactic‐acid) (hmwPLLA, Mw = 2 80 000 Da) electrospun nanofiber‐constructed yarns (ENCYs). The internal fiber diameter within the hmwPLLA ENCYs found increase gradually of solution concentration. ENCY generated from a concentration 10% (w v −1 ) demonstrated uniform morphology an average 737.7 ± 72.2 nm yarn 454.9 3.5 µm. Compared unstretched ENCY, increasing temperature can significantly enhance orientation crystallinity. Moreover, mechanical properties stretched are obviously enhanced compared control. crystallinity also be improved hot stretching rate, further resulting in obvious breaking strength Young's modulus. Importantly, braided textiles made exhibited great biocompatibility by effectively guiding cell alignment supporting adhesion proliferation. In summary, high performance show potential for future design development advanced biomedical textiles.

Язык: Английский

Процитировано

1
Epigallocatechin gallate and vancomycin loaded poly(vinyl)-pyrrolidone-gelatine nanofibers, Conceivable curative approach for wound healing DOI

Jiang Ni,

Yanhua Chen, Lan Zhang

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 249, С. 114506 - 114506

Опубликована: Янв. 15, 2025

Язык: Английский

Процитировано

0
Electrospun amine-modified polysuccinimide/polycaprolactone nanofiber hydrogel dressings as antibacterial and hemostatic wound dressing applications DOI

Jialu Pan,

Qi Meng,

Li Zhang

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114648 - 114648

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Lumbrokinase-containing gelatin nanofibers with multiple bioactivities for effective skin wound healing DOI Creative Commons
Wen-Ling Wang,

Yi-Hui Lai,

Chiung-Hua Huang

и другие.

Materials Today Bio, Год журнала: 2025, Номер 32, С. 101713 - 101713

Опубликована: Март 30, 2025

Wound healing is a highly complex and intricate biological process involving cellular molecular events. Given that lumbrokinase fibrinolytic enzyme derived from earthworms exhibits notable anti-inflammatory, anti-fibrotic, pro-angiogenic functions, this study aims to investigate the development of bioactive gelatin nanofibers containing (GLK) fabricated through electrospinning as novel nanomedicine strategy for enhancing wound healing. Our results showed reducing time can increase cross-linking degree decrease degradation rate maintain an effective concentration released LK supporting long-term processes. Cells cultured with biocompatible GLK displayed good adhesion extensive spreading, increased VEGF production, lowered IL-6 TNF-α secretion. The superior multiple bioactivities was further tested tissue regeneration potential in rat model skin defect. treatment animals shortens time, reduces damage caused by inflammation, increases collagen angiogenesis, fibroblast proliferation/epithelialization, demonstrating effect on local wounds comparable Comfeel group. Overall, findings preclinical studies suggest high promise LK-loaded biopolymer dressing materials promoting regenerative environment accelerating healing, indicating its future translational potential.

Язык: Английский

Процитировано

0
Tannic acid-etched PAN/PVP nanofibers loaded with Cu-MOFs enhance antibacterial efficacy and accelerate wound healing DOI
Zhenyu Wang, Jianxiang Li, Sihan Li

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 253, С. 114719 - 114719

Опубликована: Апрель 18, 2025

Язык: Английский

Процитировано

0
A Novel Bilayer Hydrogel/ Fibrous Wound Dressing Comprising Falcaria vulgaris Extract and Green Synthesized ZnO Nanoparticles Accelerates Wound Healing Process DOI Creative Commons

Tahereh Moshfeghi,

Najmeh Najmoddin, Elham Arkan

и другие.

Journal of Science Advanced Materials and Devices, Год журнала: 2025, Номер unknown, С. 100896 - 100896

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Fabrication and characterization of an asymmetric bilayer wound dressing for healing acceleration of full thickness wounds DOI
Farah E. Ismaeel,

Huda Raad Kareem,

Mohamed Farid Abbas

и другие.

International Journal of Pharmaceutics, Год журнала: 2025, Номер unknown, С. 125638 - 125638

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0