Fabrication and characterization of an asymmetric bilayer wound dressing for healing acceleration of full thickness wounds DOI
Farah E. Ismaeel,

Huda Raad Kareem,

Mohamed Farid Abbas

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125638 - 125638

Published: April 1, 2025

Language: Английский

Adjusting Morphology, Structure, and Mechanical Properties of Electrospun High‐Molecular‐Weight Poly(l‐Lactic‐Acid) Nanofibrous Yarns Through Hot Stretching Treatment DOI Open Access

Xiaoyu Liu,

Jiayi Jiang, Hailei Liu

et al.

Macromolecular Bioscience, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Abstract An integrated strategy that combines innovative electrospinning technique with traditional hot‐stretching post‐treatment is designed and implemented to generate high‐molecular‐weight poly(l‐lactic‐acid) (hmwPLLA, Mw = 2 80 000 Da) electrospun nanofiber‐constructed yarns (ENCYs). The internal fiber diameter within the hmwPLLA ENCYs found increase gradually of solution concentration. ENCY generated from a concentration 10% (w v −1 ) demonstrated uniform morphology an average 737.7 ± 72.2 nm yarn 454.9 3.5 µm. Compared unstretched ENCY, increasing temperature can significantly enhance orientation crystallinity. Moreover, mechanical properties stretched are obviously enhanced compared control. crystallinity also be improved hot stretching rate, further resulting in obvious breaking strength Young's modulus. Importantly, braided textiles made exhibited great biocompatibility by effectively guiding cell alignment supporting adhesion proliferation. In summary, high performance show potential for future design development advanced biomedical textiles.

Language: Английский

Citations

1
Epigallocatechin gallate and vancomycin loaded poly(vinyl)-pyrrolidone-gelatine nanofibers, Conceivable curative approach for wound healing DOI

Jiang Ni,

Yanhua Chen, Lan Zhang

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 249, P. 114506 - 114506

Published: Jan. 15, 2025

Language: Английский

Citations

0
Electrospun amine-modified polysuccinimide/polycaprolactone nanofiber hydrogel dressings as antibacterial and hemostatic wound dressing applications DOI

Jialu Pan,

Qi Meng,

Li Zhang

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114648 - 114648

Published: March 1, 2025

Language: Английский

Citations

0
Lumbrokinase-containing gelatin nanofibers with multiple bioactivities for effective skin wound healing DOI Creative Commons
Wen-Ling Wang,

Yi-Hui Lai,

Chiung-Hua Huang

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 32, P. 101713 - 101713

Published: March 30, 2025

Wound healing is a highly complex and intricate biological process involving cellular molecular events. Given that lumbrokinase fibrinolytic enzyme derived from earthworms exhibits notable anti-inflammatory, anti-fibrotic, pro-angiogenic functions, this study aims to investigate the development of bioactive gelatin nanofibers containing (GLK) fabricated through electrospinning as novel nanomedicine strategy for enhancing wound healing. Our results showed reducing time can increase cross-linking degree decrease degradation rate maintain an effective concentration released LK supporting long-term processes. Cells cultured with biocompatible GLK displayed good adhesion extensive spreading, increased VEGF production, lowered IL-6 TNF-α secretion. The superior multiple bioactivities was further tested tissue regeneration potential in rat model skin defect. treatment animals shortens time, reduces damage caused by inflammation, increases collagen angiogenesis, fibroblast proliferation/epithelialization, demonstrating effect on local wounds comparable Comfeel group. Overall, findings preclinical studies suggest high promise LK-loaded biopolymer dressing materials promoting regenerative environment accelerating healing, indicating its future translational potential.

Language: Английский

Citations

0
Tannic acid-etched PAN/PVP nanofibers loaded with Cu-MOFs enhance antibacterial efficacy and accelerate wound healing DOI
Zhenyu Wang, Jianxiang Li, Sihan Li

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 253, P. 114719 - 114719

Published: April 18, 2025

Language: Английский

Citations

0
A Novel Bilayer Hydrogel/ Fibrous Wound Dressing Comprising Falcaria vulgaris Extract and Green Synthesized ZnO Nanoparticles Accelerates Wound Healing Process DOI Creative Commons

Tahereh Moshfeghi,

Najmeh Najmoddin, Elham Arkan

et al.

Journal of Science Advanced Materials and Devices, Journal Year: 2025, Volume and Issue: unknown, P. 100896 - 100896

Published: April 1, 2025

Language: Английский

Citations

0
Fabrication and characterization of an asymmetric bilayer wound dressing for healing acceleration of full thickness wounds DOI
Farah E. Ismaeel,

Huda Raad Kareem,

Mohamed Farid Abbas

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125638 - 125638

Published: April 1, 2025

Language: Английский

Citations

0