BioNanoScience, Год журнала: 2024, Номер 15(1)
Опубликована: Дек. 12, 2024
Язык: Английский
BioNanoScience, Год журнала: 2024, Номер 15(1)
Опубликована: Дек. 12, 2024
Язык: Английский
RSC Advances, Год журнала: 2025, Номер 15(5), С. 3858 - 3903
Опубликована: Янв. 1, 2025
A sustainable and viable alternative for conventional chemical physical approaches is the green production of silver nanoparticles (SNPs) using plant extracts.
Язык: Английский
Процитировано
6Nanomaterials, Год журнала: 2025, Номер 15(5), С. 328 - 328
Опубликована: Фев. 20, 2025
This study explores the green synthesis of silver nanoparticles (AgNPs) using Cymbopogon citratus (lemongrass) extract as a reducing agent. Synthesis was confirmed by color change (light yellow to dark brown) under optimal conditions: 1.50 mM nitrate, 3.5% v/v extract, at 100 °C, with pH 9, and for 60 min. The AgNPs exhibited spherical morphology, hydrodynamic diameter 135.41 ± 49.30 nm, zeta potential -29.9 1.4 mV, crystalline structure, minimal aggregation. showed significant antibacterial activity, particularly >20 µg/well, zones inhibition varying bacterial strain. In vitro studies demonstrated anti-inflammatory, antidiabetic (α-glucosidase α-amylase inhibition), antioxidant activities, outperforming plant nearing standard efficacy higher concentrations. Cyto-toxicity indicated that were less toxic than doxorubicin but concentration-dependent effects on cancerous non-cancerous cells. Eco-toxicity assays revealed acutely controls posed risks prolonged exposure. work highlights eco-friendly their in biomedical applications, demonstrating activities.
Язык: Английский
Процитировано
2Inorganic Chemistry Communications, Год журнала: 2024, Номер 168, С. 112882 - 112882
Опубликована: Июль 24, 2024
Язык: Английский
Процитировано
13Green Chemistry Letters and Reviews, Год журнала: 2025, Номер 18(1)
Опубликована: Март 20, 2025
Язык: Английский
Процитировано
0Frontiers in Nanotechnology, Год журнала: 2025, Номер 7
Опубликована: Апрель 24, 2025
Propolis, a natural resinous substance produced by honeybees ( Apis mellifera L.), is complex mixture of over 300 bioactive compounds with significant pharmaceutical potential. In light the escalating global antimicrobial resistance crisis, there an urgent need for novel agents. This study aimed to synthesize and characterize silver nanoparticles (AgNPs) using Ethiopian propolis evaluate their antioxidant properties. The synthesis propolis-mediated (Pro-AgNPs) was optimized characterized UV-visible spectrophotometry, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD). UV-Vis spectra revealed maximum absorbance at 424 nm, confirming successful AgNPs. FT-IR analysis identified functional groups involved in nanoparticle stabilization, while XRD confirmed crystalline nature nanoparticles. SEM images spherical-shaped uniform size distribution. activity Pro-AgNPs evaluated against Gram-negative Pseudomonas aeruginosa (ATCC 27853) Gram-positive Enterococcus faecalis 29212) bacteria, demonstrating growth inhibition zones 15.67 ± 0.57 mm 17.33 1.15 mm, respectively, concentration 50 μg/mL. extract 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, revealing concentration-dependent radical scavenging activity. exhibited potent activity, IC50 value 45.54 These findings underscore potential as antimicrobials antioxidants, promising applications pharmaceuticals, cosmetics, food industry.
Язык: Английский
Процитировано
0Nanocomposites, Год журнала: 2024, Номер 11(1), С. 20 - 51
Опубликована: Дек. 28, 2024
The rise of antimicrobial resistance (AMR), particularly in pathogens like Salmonella Enterica (SE), Pseudomonas Aeruginosa (PA), Staphyloccocus Aureus (SA), Escheria Coli (EC), and Klebsiella Pneumonia (KP), has led to a critical need for alternative treatments. This review introduces the green synthesis silver nanoparticles (AgNPs) using fruit extracts as sustainable environmentally friendly approach address AMR. mechanisms AMR, overview different AgNP methods, especially bioactive compounds from plant materials, characterization factors (i.e. solvents, temperature, pH, precursor concentrations), comparison activities fruit-derived AgNPs were discussed. Additionally, future research directions focus on developing scalable, cost-effective processes, exploring synergistic effects with antibiotics, addressing challenges nanoparticle size control, stability, potential cytotoxicity.
Язык: Английский
Процитировано
1Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 39, С. 101300 - 101300
Опубликована: Авг. 9, 2024
Язык: Английский
Процитировано
03 Biotech, Год журнала: 2024, Номер 14(11)
Опубликована: Окт. 5, 2024
Язык: Английский
Процитировано
0Chemistry & Biodiversity, Год журнала: 2024, Номер unknown
Опубликована: Окт. 22, 2024
Abstract The development of effective treatments for dental pathogens and oral cancer remains a significant challenge. Copper oxide nanoparticles (CuO NPs) are recognized their strong antimicrobial properties, attributed to the synthesis oxygen‐dependent radicals. α‐Mangostin (MG), natural xanthone from mangosteen fruit, is well‐known its antioxidant, antimicrobial, anticancer potential. combination CuO NPs with MG would offer synergistic approach enhance therapeutic efficacy. CuO‐MG were synthesized characterized size, morphology, surface properties. efficacy these was tested against pathogens, including Staphylococcus aureus , Enterococcus faecalis Streptococcus mutans Candida albicans . Antioxidant activity assessed using superoxide anion hydroxyl radical anion. potential evaluated by examining apoptosis induction in cell lines, focusing on expression key apoptotic markers such as Caspase‐3, Caspase‐8, FasL. Molecular docking simulations performed understand interaction between biofilm receptors. evidenced all enhanced combined effects CuO‐induced oxidative stress properties MG. assays demonstrated dose‐dependent increase scavenging activity. In cells, significantly reduced viability induced apoptosis, up‐regulation studies revealed binding affinities receptors, disrupting pathogen adhesion formation. offers powerful multifaceted healthcare. demonstrate offering management infections cancer. Further preclinical clinical recommended ensure safety stability medical applications.
Язык: Английский
Процитировано
0Applied In Vitro Toxicology, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 13, 2024
Язык: Английский
Процитировано
0