Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges

Heliyon, Год журнала: 2024, Номер 10(2), С. e24355 - e24355

Опубликована: Янв. 1, 2024

Microplastics have become omnipresent in the environment, including air we inhale, water consume, and food eat. Despite limited research, accumulation of microplastics within human respiratory system has garnered considerable interest because its potential implications for health. This review offers a comprehensive examination impacts stemming from on lung airways explores computational benefits challenges associated with studying this phenomenon. The existence can lead to range adverse effects. Research indicated that induce inflammation, oxidative stress, impaired function. Furthermore, small size allows them penetrate deep into lungs, reaching alveoli, where gas exchange takes place. raises concerns about long-term health consequences, such as development diseases translocation other organs. Computational approaches been instrumental understanding impact microplastic deposition airways. models simulations enable investigation particle dynamics, patterns, interaction mechanisms at various levels complexity. However, using methods presents several challenges. complex anatomy physiological processes require accurate representation models. Obtaining relevant data model validation parameterization remains significant hurdle. Additionally, diverse nature microplastics, variations size, shape, chemical composition, poses capturing their full behaviours toxicological

Язык: Английский

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Abundance and composition of microplastics in Tampico beach sediments, Tamaulipas State, southern Gulf of Mexico

Marine Pollution Bulletin, Год журнала: 2023, Номер 191, С. 114891 - 114891

Опубликована: Апрель 7, 2023

Язык: Английский

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Microplastic pollution: An emerging contaminant in aquaculture

Aquaculture and Fisheries, Год журнала: 2023, Номер 8(6), С. 603 - 616

Опубликована: Фев. 24, 2023

Aquaculture largely contributes to aquatic products and consequential dietary protein for many households. Aquaculture, just like every other food sector, is faced with enormous challenges such as unfavorable climatic events, environmental stressors contaminants. Microplastics (MP) are emerging contaminants in aquaculture following their perturbing occurrence cultured fish, fishmeal aquafeed. Several MPs pathways into facilities include wastewater, pipe-borne water, dilapidated facilities, fish gears, aquafeed stuff (fishmeal). Techniques the digestion, identification characterization of critical understanding pathways, bioavailability bioaccumulation patterns species. The impacts on species identified impaired growth, oxidative stress, neurotoxicity, reproductive toxicity, immunotoxicity, embryotoxicity, histopathology. Bioaccumulation tissues biological systems have been evidenced several fishes. Mitigation efforts cum strategies upgrade wastewater treatment screening inlet pond stuff, regular maintenance repair culture could be effective eradicate MP contamination aquaculture. Additionally, regulatory policy use plastics key mitigating impact ensure cleaner sustainable

Язык: Английский

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Microplastic pollution as an environmental risk exacerbating the greenhouse effect and climate change: a review

Carbon Research, Год журнала: 2024, Номер 3(1)

Опубликована: Янв. 26, 2024

Abstract Microplastics are polymer-based materials with carbon as their main framework. During degradation, they release greenhouse gases such dioxide and methane. Additionally, environmental microplastics can enter plant tissues, triggering oxidative stress in cells, adversely affecting photosynthesis, metabolism, gene expression, other growth parameters. This reduction efficiency sequestering utilizing atmospheric indirectly impacts global cycling, exacerbating the effect. Furthermore, significantly alter soil structure composition of microbial communities, emissions dioxide, methane, nitrous oxide, thus promoting gas emissions. Increasing research suggests a mutual reinforcement between microplastic pollution climate warming, where exacerbates rise average temperature leads to resuspension sediments, intensifying environment. article primarily focuses on different ecosystems relationship warming. It summarizes effects marine, terrestrial, ecosystems, well mechanisms by which change affect ecosystem services. By delving into intricate connection emissions, this paper aims raise awareness caused calls for further change, ultimate goal protecting human health. Graphical

Язык: Английский

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Ferroptosis Induced by Pollutants: An Emerging Mechanism in Environmental Toxicology

Environmental Science & Technology, Год журнала: 2024, Номер 58(5), С. 2166 - 2184

Опубликована: Янв. 26, 2024

Environmental pollutants have been recognized for their ability to induce various adverse outcomes in both the environment and human health, including inflammation, apoptosis, necrosis, pyroptosis, autophagy. Understanding these biological mechanisms has played a crucial role risk assessment management efforts. However, recent identification of ferroptosis as form programmed cell death emerged critical mechanism underlying pollutant-induced toxicity. Numerous studies demonstrated that fine particulates, heavy metals, organic substances can trigger ferroptosis, which is closely intertwined with lipid, iron, amino acid metabolism. Given growing evidence linking severe diseases such heart failure, chronic obstructive pulmonary disease, liver injury, Parkinson's Alzheimer's cancer, it imperative investigate ferroptosis. In this review, we comprehensively analyze pathways intricate signaling molecules elucidate integration into driving braking axes. Furthermore, discuss potential hazards associated organs four representative animal models. Finally, provide an outlook on future research directions strategies aimed at preventing By enhancing our understanding novel developing effective preventive measures, mitigate effects environmental safeguard health.

Язык: Английский

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