Nano-selenium protects grass carp hepatocytes against 4-tert-butylphenol-induced mitochondrial apoptosis and necroptosis via suppressing ROS-PARP1 axis

Fish & Shellfish Immunology, Год журнала: 2023, Номер 135, С. 108682 - 108682

Опубликована: Март 14, 2023

Язык: Английский

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Isomer-specific cardiotoxicity induced by tricresyl phosphate in zebrafish embryos/larvae

Journal of Hazardous Materials, Год журнала: 2024, Номер 474, С. 134753 - 134753

Опубликована: Май 29, 2024

Язык: Английский

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Abiotic degradation and accelerated ageing of microplastics from biodegradable and recycled materials in artificial seawater

The Science of The Total Environment, Год журнала: 2024, Номер 954, С. 176832 - 176832

Опубликована: Окт. 9, 2024

Microplastics (MPs) are considered one of the most widespread pollutants in all ecosystems worldwide. In environment, MPs can undergo hydrolysis and/or oxidation, resulting release low-molecular weight degradation products, along with additives, and adsorbed organic pollutants. this study, morphological, chemical, thermal changes microplastics obtained from two biodegradable plastics, polylactic acid Mater-Bi®, a recycled plastic, recycled-polyethylene terephthalate, were examined after accelerated ageing under photo-oxidative conditions synthetic seawater Solarbox system, treatment dark. Thermal properties studied by thermogravimetric analysis, differential scanning calorimetry, evolved gas analysis-mass spectrometry. Compositions chemical components polymers evaluated attenuated total reflection-Fourier transform infrared spectroscopy pyrolysis-gas chromatography-mass The leachable fractions products released degraded characterized This study allowed us to identify as main pathway characterize not only oligomers water consequence degradation, but also additives used plastic item formulations. improves our understanding these polymers' behavior conditions.

Язык: Английский

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Screening for Endocrine Bioactivity Potential of Tobacco Product Chemicals Including Flavor Chemicals

Environmental Toxicology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

Adolescence and pregnancy involve elevated levels of hormones (e.g., estrogen, androgen) during which exposure to endocrine disruptors could have long-term developmental reproductive toxicity (DART) effects. Therefore, the use prevalence abuse liability electronic nicotine delivery systems (ENDS) among adolescents youth, pregnancy, raises concerns about possible disruptors. In addition, adverse effects on wildlife environmental health. While many studies focus carcinogenicity mutagenicity tobacco products, research efforts screening chemicals in products for disruption potential are few. this study, we curated 5179 smoke, 2803 flavor chemicals, 156 e-liquid from literature or openly available databases. We screened bioactivity using new approach methodologies (NAMs) developed through US Environmental Protection Agency's Endocrine Disruptor Screening Program. The specific NAMs, estrogenic androgenic pathway models, identified 137 34 three (Veratraldehyde, (2E)-3-Phenylprop-2-enal, 2'-Acetonaphthone) as "active," indicating bioactivity. Further, with potential, 48 were environmentally persistent, 29 bioaccumulative, 19 both persistent bioaccumulative. Our findings document bioactivity, human These results also underscore importance DART flavors. Overall, our study characterizes provides a list consider future ecological health risk assessments.

Язык: Английский

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Impact of 4-tert-Butylphenol on Inflammation and Glycogen Metabolism in Cyprinus carpio L via the miR-363/PKCδ Axis

Environment & Health, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Язык: Английский

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A comprehensive metabolomic and lipidomic study of olanzapine in the treatment of first-episode schizophrenia

Asian Journal of Psychiatry, Год журнала: 2025, Номер 105, С. 104387 - 104387

Опубликована: Фев. 19, 2025

Язык: Английский

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Tert-butylphenol exposure alters cartilage and bone development in zebrafish

Chemosphere, Год журнала: 2025, Номер 376, С. 144300 - 144300

Опубликована: Март 16, 2025

Язык: Английский

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4-tert-Butylphenol impairs the liver by inducing excess liver lipid accumulation via disrupting the lipid metabolism pathway in zebrafish

Environmental Pollution, Год журнала: 2024, Номер 356, С. 124385 - 124385

Опубликована: Июнь 17, 2024

Язык: Английский

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Environmental endocrine disrupting chemical 4-tert-butylphenol induced calcium overload and subsequent autophagy impairment via miRNA-363/CACNA1D Axis in epithelioma papulosum cyprini cells

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Год журнала: 2024, Номер 283, С. 109968 - 109968

Опубликована: Июнь 28, 2024

Язык: Английский

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Exposure Profile and Characteristics of Parabens and Alkylphenols in Plasma among Rural Adults in Central China

Toxics, Год журнала: 2023, Номер 11(11), С. 926 - 926

Опубликована: Ноя. 13, 2023

Parabens and alkylphenols pose serious hazards to human health, yet there are few studies on their exposure profiles health risks in rural Chinese populations. In this study, 804 participants were selected from the Henan Rural Cohort mid-eastern China. The plasma levels of parabens (methylparaben, ethylparaben, propylparaben, butylparaben (BuP)) (4-tert-butylphenol (4-t-BP), 4-tert-octylphenol (4-t-OP)) analyzed via liquid chromatography-tandem mass spectrometry. Linear regression models used investigate factors that may influence pollutant levels. correlation between contaminants was assessed using Spearman's correlation. contaminant intake estimated daily (EDI). risk hazard quotient (HQ). detection frequency four two exceeded 75%, with median concentrations 0.444, 0.067, 0.078, 0.053, 8.810, 6.401 ng/mL, respectively. Significant correlations observed parabens, as well 4-t-BP 4-t-OP. Regarding gender, paraben higher women than men, except for BuP. EDI pollutants 4-t-OP lower respective tolerable/acceptable intake. total, 85.70% had HQ > 1. A widespread among population found. high alkylphenol indicate should be caution.

Язык: Английский

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