Nutrients,
Год журнала:
2024,
Номер
16(9), С. 1377 - 1377
Опубликована: Май 1, 2024
The
SYNERGIE
study
documented
the
effects
on
cardiometabolic
risk
(CMR)
indices
of
a
1-year
lifestyle
intervention
targeting
physical
activity
(PA)
and
diet
followed
by
2-year
maintenance
period
in
men
with
visceral
obesity.
Improvements
CMR
markers
decrease
low-attenuation
muscle
(LAM)
area
were
observed
after
1
year.
Despite
rebound
adipose
tissue
(VAT)
during
period,
insulin
resistance
(IR)
improved.
We
tested
hypothesis
that
variations
cardiorespiratory
fitness
(CRF)
LAM
could
explain
long-term
improvement
IR.
A
health
(n
=
88;
mean
age
49.0
±
8.2
years)
72)
evaluation
was
performed
at
0,
1,
3
years.
Participants
classified
into
two
groups
based
their
CRF
response
over
(worsening:
CRF−
vs.
maintenance/improvement:
CRF+).
During
changes
psoas
core
areas
correlated
IR
(r
0.27;
p
<
0.05
r
0.34;
0.005)
−0.31;
0.01
−0.30;
0.05).
improved
CRF+
group
(p
0.05)
but
remained
stable
group.
Men
regained
half
VAT
volume
mid-thigh
compared
to
These
results
support
importance
CRF/PA
for
management
Clinical and Experimental Hypertension,
Год журнала:
2023,
Номер
45(1)
Опубликована: Окт. 8, 2023
Obesity,
especially
visceral
obesity,
plays
an
important
role
in
the
progression
of
cardiovascular
disease
(CVD).
The
body
roundness
index
(BRI)
is
a
new
measure
obesity
that
considered
to
reflect
more
comprehensively
than
other
measures.
This
study
aims
evaluate
relationship
between
BRI
and
CVD
risk
hypertensive
patients
with
obstructive
sleep
apnea
(OSA)
explore
its
superiority
predicting
CVD.The
Cox
proportional
hazards
model
was
used
calculate
hazard
ratios
(HRs)
95%
confidence
intervals
(CIs)
for
incident
CVD.
area
under
curve
(AUC),
continuous
net
reclassification
improvement
(NRI),
integrated
discrimination
(IDI)
were
assess
which
measures
had
best
predictive
value
risk.During
median
follow-up
period
6.8
years,
324
participants
suffered
event.
After
multivariable
adjustment,
compared
reference
group
(the
first
tertile),
HRs
(95%
CI)
1.25
CI,
0.93-1.70)
1.74
1.30-2.33)
subjects
tertile
2
3
groups,
respectively.
Compared
measurement
indicators,
has
highest
[AUC:
0.627,
CI:
0.593-0.661].
addition
fully
adjusted
multivariate
improved
power
CVD,
validated
NRI
IDI
(all
P
<
.05).BRI
significantly
associated
OSA.
Furthermore,
may
improve
prediction
Frontiers in Nutrition,
Год журнала:
2025,
Номер
11
Опубликована: Янв. 6, 2025
Research
suggests
a
potential
connection
between
cardiovascular
health,
obesity,
and
overactive
bladder
(OAB).
However,
the
mechanisms
by
which
obesity
influences
relationship
health
OAB
remain
unclear.
Life's
Crucial
9
(LC9)
is
recently
proposed
method
for
assessing
while
weight-adjusted
waist
index
(WWI)
novel
more
accurate
measure
of
obesity.
This
study
investigates
LC9
assesses
whether
WWI
moderates
this
relationship.
Data
came
from
National
Health
Nutrition
Examination
Survey
(NHANES).
We
used
subgroup
analyses,
restricted
cubic
spline
curves
(RCS),
multivariate
logistic
regression
to
explore
OAB.
Additionally,
mediation
analysis
was
conducted
investigate
association
levels
A
total
25,319
participants
were
included
in
study,
among
5,038
reported
incidents
After
adjusting
all
variables
using
multivariable
regression,
an
increase
10
units
associated
with
28%
reduction
incidence
(OR
=
0.72,
95%
CI:
0.69,
0.76),
one
unit
40%
1.40,
1.29,
1.51).
Consistent
results
also
observed
when
categorized
into
quartiles,
P
trend
<0.001.
The
splines
indicated
linear
negative
correlation
LC9.
Mediation
revealed
that
13.89%
mediated
(p
0.002).
found
significant
OAB,
acting
as
partial
mediator
provides
new
insights
future
research
role
mediator.
Foods,
Год журнала:
2024,
Номер
13(16), С. 2619 - 2619
Опубликована: Авг. 21, 2024
Several
studies
suggested
a
negative
association
between
olive
oil
(OO)
consumption
and
the
risk
of
several
chronic
diseases.
However,
an
attempt
to
systematically
search,
organize,
evaluate
existing
evidence
on
all
health
outcomes
associated
with
OO
is
lacking.
The
objective
this
review
describe
multiple
consumption.
Medline,
Scopus,
Web
Science
databases
were
searched
through
5
April
2024.
selected
met
following
criteria:
(1)
meta-analysis
both
observational
(case–control
cohort
studies)
interventional
(trials),
(2)
evaluation
consumption,
mortality,
and/or
incidence
non-communicable/chronic
degenerative
diseases,
(3)
study
population
≥18
years
old.
Two
independent
reviewers
extracted
relevant
data
assessed
bias
individual
studies.
PRISMA
statement
guidelines
for
Integration
Evidence
from
Multiple
Meta-Analyses
followed.
literature
search
identified
723
articles.
After
selection,
31
articles
included
in
umbrella
review.
primary
benefits
observed
cardiovascular
diseases
factors,
cancer,
diabetes,
specific
biomarkers
related
anthropometric
status
inflammation.
As
key
component
Mediterranean
diet,
can
be
considered
healthy
dietary
choice
improving
positive
outcomes.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Окт. 27, 2024
The
objective
of
this
study
was
to
ascertain
the
relationship
between
weight-adjusted
waist
index
(WWI)
and
risk
stroke
in
an
elderly
hypertensive
population,
a
that
has
not
been
previously
elucidated.
Cox
regression
model
employed
assess
correlation
baseline
WWI
measurements
incidence
stroke.
To
further
elucidate
shape
association
stroke,
restricted
cubic
splines
were
employed.
Furthermore,
subgroup
analyses
interaction
tests
carried
out
investigate
potential
heterogeneities.
Our
cohort
comprised
4962
individuals
aged
60
years
or
older
with
no
prior
history
Over
median
follow-up
3.2
years,
we
found
547
new-onset
cases.
After
adjusting
for
confounding
variables,
analysis
revealed
positive
hazard
ratios
(HRs)
escalating
progressively
as
values
increased.
When
compared
lowest
quartile
WWI,
highest
demonstrated
HR
1.87
(95%
CI,
1.44–2.42)
Subgroup
confirmed
consistency
across
different
demographic
clinical
strata.
findings
indicate
elevated
is
significantly
related
higher
among
patients
hypertension.
These
results
underscore
importance
stratification
tool.
confirm
these
explore
causal
mechanisms
behind
observed
correlation,
more
necessary.
Cardiovascular Diabetology,
Год журнала:
2023,
Номер
22(1)
Опубликована: Апрель 3, 2023
Coronary
artery
calcium
(CAC)
improves
cardiovascular
event
prediction.
Visceral
adipose
tissue
(VAT)
is
a
cardiometabolic
risk
factor
that
may
directly
or
through
its
related
comorbidities
determine
the
obesity-related
risk.
A
clinical
VAT
estimator
could
allow
an
efficient
evaluation
of
We
aimed
to
analyze
effect
and
factors
on
CAC
progression.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(19), С. 14651 - 14651
Опубликована: Сен. 27, 2023
A
fatty
liver
index
(FLI)
greater
than
sixty
(FLI
≥
60)
is
an
established
score
for
metabolic
dysfunction-associated
steatotic
disease
(MASLD),
which
carries
a
high
risk
diabetes
and
cardiovascular
disease,
while
FLI
≤
20
rules
out
the
presence
of
steatosis.
Thus,
we
investigated
whether
was
associated
with
cardiometabolic
factors,
i.e.,
visceral
(VAT),
subcutaneous
(SC),
epicardial
(EPI),
extrapericardial
(PERI),
total
cardiac
(CARD-AT)
adipose
tissue,
hepatic
fat
((by
magnetic
resonance
imaging,
MRI,
spectroscopy,
MRS),
insulin
resistance
(IR,
HOMA-IR
OGIS-index),
components
syndrome.
All
individuals
60
had
MASLD,
none
steatosis
(by
MRS).
Subjects
higher
BMI
(VAT
>
1.7
kg,
CARD-AT
0.2
kg).
positively
increased
FLI,
VAT,
were
all
IR,
blood
pressure,
cholesterol,
reduced
HDL.
For
60,
cut-off
values
depots
laboratory
measures
estimated.
In
conclusion,
identified
not
only
subjects
but
also
those
abdominal
accumulation,
hyperlipidemia,
at
diseases.
Targeted
reduction
would
help
reduce
risk.
Frontiers in Endocrinology,
Год журнала:
2024,
Номер
15
Опубликована: Июль 8, 2024
Objective
Perirenal
adipose
tissue
(PAT)
has
emerged
as
a
potential
therapeutic
target
for
cardiovascular
disease
(CVD).
However,
the
relationship
between
increased
perirenal
fat
thickness
(PrFT)
and
CVD
risks
in
individuals
with
type
2
diabetes
mellitus
(T2DM)
remains
uncertain.
This
study
aimed
to
evaluate
association
PrFT
estimated
10-year
risk
of
atherosclerotic
(ASCVD)
T2DM.
Method
The
final
analysis
included
704
participants.
was
quantified
using
non-enhanced
computed
tomography
scans,
while
ASCVD
assessments
were
based
on
Framingham
China-PAR
equation
scores,
respectively.
Multiple
regression
employed
analyze
correlation
these
scores.
Results
Higher
quartiles
displayed
elevated
scores
(
P
<0.001).
After
adjusting
cardiometabolic
factors
visceral
area,
remained
significantly
correlated
men
β
=0.098,
=0.036)
women
=0.099,
=0.032).
Similar
correlations
observed
=0.106,
=0.009)
=0.108,
=0.007).
Moreover,
an
independent
variable
associated
high
ASCVD,
odds
ratios
(ORs)
1.14
(95%
CI:
1.04-1.25,
=0.016)
1.20
1.11-1.31,
<0.001)
risk,
ORs
1.22
1.08-1.41,
1.34
1.12-1.60,
risk.
Furthermore,
restricted
cubic
spline
analyses
confirmed
nonlinear
both
genders
nonlinearity
overall
<
0.05).
Conclusions
contributed
Nutrients,
Год журнала:
2022,
Номер
14(15), С. 3075 - 3075
Опубликована: Июль 27, 2022
The
extraskeletal
effect
of
vitamin
D
on
adipose
tissue
biology
and
modulation
in
human
obesity
is
great
interest
has
been
extensively
investigated.
Current
evidence
from
preclinical
clinical
studies
suggests
that
the
anti-inflammatory
effects
are
evident
consistent,
whereas
adipocyte
differentiation,
adipogenesis,
energy
metabolism
supplementation
adipokine
levels
inconclusive.
Interventional
related
to
medical
surgical
weight
loss
humans
have
shown
small
or
no
improvement
status.
Additionally,
benefit
for
reduction
visceral
only
demonstrated
a
few
studies.
Overall,
findings
relationship
between
still
Further
required
confirm
beneficial
ameliorating
dysfunction.
