International Journal of Environmental Research and Public Health,
Год журнала:
2023,
Номер
20(2), С. 1250 - 1250
Опубликована: Янв. 10, 2023
Arterial
hypertension
(AH),
one
of
the
most
common
diseases
civilization,
is
an
independent
risk
factor
for
cardiovascular
morbidity
and
mortality.
This
disease
second,
after
lipid
disorders,
a
significant
cause
premature
death.
In
Poland,
in
three
adults
(approximately
11
million
people)
suffers
from
it.
The
aim
our
survey
was
to
determine
patients’
knowledge
factors
(e.g.,
age,
smoking
cigarettes,
drinking
coffee,
shift
work)
that
may
influence
development
hypertension.
conducted
among
205
adult
primary
care
patients
living
urban
areas.
There
high
correlation
between
education
AH,
such:
as
excess
salt
diet
(p
=
0.038),
electronic
cigarettes
0.005),
moderate
alcohol
consumption
0.028),
daily
physical
activity
0.011),
female
male
sex
0.032
p
0.012),
air
pollution
<
0.001)
others.
addition,
statistically
shaping
attitudes
toward
prevention
respondents’
their
parents’
prevalence
0.40).
study
increases
awareness
It
serve
guidance
providers
pay
special
attention
environmental
interviews
with
patient’s
family
history
incidence.
BIO Web of Conferences,
Год журнала:
2025,
Номер
165, С. 07002 - 07002
Опубликована: Янв. 1, 2025
The
massive
growth
through
the
trends
toward
coffee-lover
communities
has
pushed
new
revolution
of
coffee
waves
in
Indonesia,
previously
from
second
wave
into
third
wave.
In
Malang
area,
this
phenomenon
at
same
time
had
brought
challenges
and
opportunities,
especially
improving
awareness
for
lovers,
which
a
major
role
as
coffee-shop
customers.
Moreover,
study
focused
on
describing
customers
semi-trained
testers
perspectives
towards
taste
available
species
is
provided
by
experiences
simple
public
cupping.
As
many
31
9
have
been
chosen
demonstration
was
conducted
Bumi
Kopi
Coffee
Shop,
Malang.
Four
types
samples;
including
Coffea
arabica
var
typica
(arabica),
liberica
(liberica),
canephora
robusta
(robusta),
Coffea.
dewevrei
(excelsa)
used
during
test.
findings
based
test
showed
that
semi
trained
tend
to
enjoy
fruity
such
found
liberica,
while
excelsa
also
still
enjoyed
fewer
Based
research,
its
hoped
if
these
activities
could
be
improved,
an
creative
business
optimization
part
gastronomic
tourism.
Molecular Nutrition & Food Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 22, 2025
ABSTRACT
Yerba
mate
has
been
reported
to
have
antihypertensive,
hypocholesterolemic,
antidiabetic,
or
antiobesity
properties.
Most
evidences
from
human
trials
involved
intakes
of
high
amounts
by
habitual
consumers.
Considering
its
increasing
popularity,
this
study
aimed
at
assessing
the
potential
cardiometabolic
effects
moderate
intake
yerba
nonhabitual
A
randomized,
crossover,
controlled
was
carried
out
in
healthy
and
hypercholesterolemic
subjects.
Anthropometric
parameters,
blood
pressure,
lipids,
glucose
metabolism,
inflammatory
cytokines,
chemokines,
different
markers
endothelial
function,
as
well
incretins,
adipocytokines,
hormones
were
measured
baseline
after
8
weeks
consuming
a
decaffeinated
isotonic
drink
(control).
After
daily
consumption
three
servings
tea,
colony‐stimulating
factors
decreased
all
participants.
LDL‐C
normocholesterolemic
individuals,
while
control
interventions
elicited
similar
hypolipidemic
action
group.
Ghrelin
glucose‐dependent
insulinotropic
polypeptide
(GIP)
significantly
intake,
glucagon‐like
peptide
1
(GLP‐1)
adipocytokines
remained
unchanged.
Body
fat
percentage
tricipital
skinfold
only
subjects,
with
no
on
total
body
weight.
In
conclusion,
could
exert
protective
consumers
subjects
cardiovascular
risk.
Trial
Registration
:
This
trial
retrospectively
registered
ClinicalTrials
(NCT06729905)
Cardiology Journal,
Год журнала:
2022,
Номер
30(4), С. 654 - 667
Опубликована: Авг. 1, 2022
Coffee,
next
to
water,
is
the
most
consumed
drink
in
world.
Coffee
contains
over
1000
chemical
compounds,
popular
of
which
are
caffeine,
chlorogenic
acid,
kahweol,
cafestol
and
trigonelline.
Numerous
studies
have
shown
beneficial
effects
coffee
on
cardiovascular
system,
nervous
digestive
system
kidneys.
Due
high
incidence
cardiac
arrhythmias,
especially
atrial
fibrillation,
influence
consumption
arrhythmogenesis
remains
a
controversial
clinically
important
issue.
Many
mechanisms
by
can
increase
decrease
risk
arrhythmias
been
described.
Habitual
moderate
amounts
seems
lead
less
reflected
results
many
clinical
trials
meta-analyzes.
This
review
summarizes
action
heart
muscle
recent
assessing
impact
various
arrhythmias.
Phytomedicine,
Год журнала:
2023,
Номер
120, С. 155033 - 155033
Опубликована: Авг. 17, 2023
Hypertension
is
a
serious
global
public
health
issue.
Blood
pressure
(BP)
still
not
effectively
controlled
in
about
20
-
30%
of
hypertensive
patients.
Therefore,
it
imperative
to
develop
new
treatments
for
hypertension.
Veratrum
alkaloids
were
once
used
the
clinical
treatment
hypertension,
mechanism
which
unclear.
It
was
gradually
phased
out
due
adverse
reactions.This
study
aimed
investigate
short-term
and
long-term
hypotensive
profiles
different
components
spontaneously
rats
(SHRs)
unveil
their
mechanisms
action.Total
alkaloid
(V),
component
A
(A),
veratramine
(M)
quickly
decreased
BP
within
30
min
treatment,
reduced
renal
cardiovascular
damage,
improved
relevant
biochemical
indicators
(nitric
oxide
[NO],
endothelin-1
[ET-1],
angiotensin
II
[Ang
II)],
noradrenaline
[NE],
etc)
SHRs
delay
stroke
occurrence.
Thereinto,
exhibited
excellent
protective
effects
disease.
The
metabolomic
treated
with
V,
A,
M
significantly
from
those
vehicle.
Thirteen
metabolites
identified
as
potential
pharmacodynamic
biomarkers.
Through
Kyoto
Encyclopedia
Genes
Genomes
analysis,
M-induced
hypotension
mainly
related
alterations
nicotinate
nicotinamide
metabolism,
GABAergic
synapses,
linoleic
acid
ketone
body
synthesis
degradation,
arginine
proline
urea
cycle,
metabolism
key
metabolic
pathway
relieve
hypertension.This
work
shows
that
an
effective
promising
antihypertensive
agent
hypertension
reduce
target
organ
mediated
through
modulating
RAS,
NO-ET
homeostasis.
Medicina,
Год журнала:
2023,
Номер
59(10), С. 1789 - 1789
Опубликована: Окт. 8, 2023
Metabolic-associated
Fatty
Liver
Disease
is
one
of
the
outstanding
challenges
in
gastroenterology.
The
increasing
incidence
disease
undoubtedly
connected
with
ongoing
obesity
pandemic.
lack
specific
symptoms
early
phases
and
grave
complications
require
an
active
approach
to
prompt
diagnosis
treatment.
Therapeutic
lifestyle
changes
should
be
introduced
a
great
majority
patients;
but,
many
cases,
adherence
not
satisfactory.
There
need
for
effective
pharmacological
therapy
Metabolic-Associated
Disease,
especially
before
onset
steatohepatitis.
Currently,
there
are
no
recommendations
on
selection
drugs
treat
liver
steatosis
prevent
patients
from
progression
toward
more
advanced
stages
(steatohepatitis,
cirrhosis,
cancer).
Therefore,
this
Review,
we
provide
data
clinical
efficacy
therapeutic
interventions
that
might
improve
course
Disease.
These
include
used
treatment
hyperlipidemias,
as
well
affecting
gut
microbiota
endocrine
system,
other
experimental
approaches,
including
functional
foods.
Finally,
advice
concomitant
Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Дек. 20, 2022
Caffeine
is
widely
consumed
not
only
in
coffee
but
also
soft
drinks
and
tea.
However,
the
long-term
health
effects
of
caffeine
are
still
controversial,
especially
people
with
high
cardiovascular
risk
such
as
elderly
patients
hypertension.This
study
analyzed
data
from
National
Health
Nutrition
Examination
Survey
2003-2018.
intake
was
calculated
by
two
24-h
dietary
recall
interviews.
Complex
sampling-weighted
multivariable
Cox
proportional
hazards
models
were
used
to
compare
hazard
ratios
(HRs)
all-cause
mortality
hypertensive
different
(<10,
10
<100,
100
<200,
200
<300,
≥300
mg/day).This
included
6,076
patients.
The
mean
±
standard
error
follow-up
duration
6.86
0.12
years.
During
this
period,
a
total
2,200
deaths
occurred,
which
765
deaths.
Taking
<
mg/day
reference,
moderate
(200
<300
mg/day)
had
lower
(HR,
0.70
[95%
CI,
0.56-0.87])
0.55
0.39-0.77])
mortality.
benefit
reducing
significant
female
0.65
0.50-0.85])
or
well-controlled
blood
pressure
0.63
0.46-0.87]),
male
poorly
controlled
pressure.
In
addition,
non-linear
relationship
analysis
showed
that
lowest
HRs
(Non-linear
p
=
0.022)
0.032)
present
study.Moderate
associated
reduced
Global Cardiology Science and Practice,
Год журнала:
2023,
Номер
2023(2)
Опубликована: Май 8, 2023
Coffee
is
a
popular
beverage
and
the
most
used
psychostimulant
worldwide.
Habitual
coffee
consumption
has
been
linked
to
growing
list
of
health
benefits;
however,
source
longstanding
debate.
Recent
observational
studies
have
challenged
misconception
caffeine
reported
safety
beneficial
effects
intake
on
range
cardiovascular
(CV)
conditions,
including
coronary
artery
disease,
arrhythmias,
heart
failure,
stroke,
leading
decreased
risk
CVD,
all-cause
CVD
mortality,
being
associated
with
favorable
CV
outcomes.
However,
mechanisms
underlying
protective
remain
speculative,
there
lack
dedicated
aimed
at
addressing
impact
different
subtypes
clinical
outcomes
such
as
arrhythmia,
mortality.
Study
Results:
The
study
included
449,563
UK
Biobank
participants,
free
problems
enrollment
(median
age
58
years;
55.3%
females).
median
follow-up
time
was
12.5
years.
Drinking
4
5
cups/day
ground
(HR
0.83;
95%
CI
[0.76-0.91];
P
<
.0001)
or
2
3
instant
(HR,
0.88;
[0.85-0.92];
(but
not
decaffeinated
coffee)
significant
reduction
in
incident
AF.
up
reductions
CHD
0.89,
[0.86-0.91],
0.0001),
CCF
0.83,
[0.79-0.87],
ischemic
stroke
0.84,
[0.78-0.90],
0.0001).
led
mortality
0.86,
[0.83-0.89],
0.0001)
0.82,
[0.74-0.90],
Consumption
all
levels
significantly
reduced
There
no
difference
incidence
among
categories
across
subtypes.The
results
from
indicate
that
mild-to-moderate
types
improved
lower
disease
death,
caffeinated
reducing
Daily
should
be
discouraged
by
physicians,
even
presence
newly
developed
disease.
Whether
will
prescribed
future
prevent
improve
depends
further
evaluation
physiological
elucidation
specific
consumption.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Май 31, 2024
Background
The
use
of
herbal
medicines
(HMs)
for
the
treatment
hypertension
(HTN)
is
increasing
globally,
but
research
on
potential
adverse
effects
and
safety
HMs
in
HTN
patients
limited.
Therefore,
this
systematic
review
meta-analysis
aim
to
determine
global
prevalence
HM
usage
among
assess
identified
herbs
based
current
scientific
evidence.
Methods
PubMed/MEDLINE,
EMBASE
(Ovid),
Cumulated
Index
Nursing
Allied
Health
Literature
(CINAHL)
databases
were
searched
cross-sectional
studies
patients.
Our
includes
published
English
up
year
2023.
After
extracting
appraising
data
from
studies,
a
was
conducted
using
Stata
version
16.0
estimate
pooled
with
(PROSPERO:
CRD42023405537).
classification
done
existing
literature.
Results
This
study
analyzed
37
21
countries
found
that
37.8%
used
manage
their
health.
varied
significantly
publication
geographical
region.
Among
71
herbs,
Allium
sativum
L.,
Hibiscus
sabdariffa
Olea
europaea
L.
most
commonly
used.
However,
four
as
contraindicated,
50
required
caution,
only
11
considered
safe
use.
Conclusion
highlights
risks
toxicities
associated
HTN.
Ensuring
patient
involves
appropriate
doses
avoiding
contraindicated
HMs.
Future
should
focus
identifying
especially
resource-limited
poor
management,
additional
clinical
toxicity