A mini review on green nanotechnology and its development in biological effects

Archives of Microbiology, Год журнала: 2023, Номер 205(4)

Опубликована: Март 22, 2023

The utilization of living organisms for the creation inorganic nanoscale particles is a potential new development in realm biotechnology. An essential milestone nanotechnology process creating dependable and environmentally acceptable metallic nanoparticles. Due to its increasing popularity ease, use ambient biological resources quickly becoming more significant this field study. phrase "green nanotechnology" has gained lot attention refers variety procedures that eliminate or do away with hazardous compounds repair environment. Green nanomaterials can be used biotechnological sectors such as medicine biology, well food textile industries, wastewater treatment agriculture field. construction an updated level knowledge study systems might support revolutionize nanoparticles (NPs) are presented article.

Язык: Английский

---

Biosynthesis of Silver and Gold Nanoparticles and Their Efficacy Towards Antibacterial, Antibiofilm, Cytotoxicity, and Antioxidant Activities

Applied Biochemistry and Biotechnology, Год журнала: 2022, Номер 195(2), С. 1158 - 1183

Опубликована: Ноя. 7, 2022

The World Health Organization (WHO) reports that the emergence of multidrug-resistant and slow advent novel more potent antitumor antimicrobial chemotherapeutics continue to be highest concern for human health. Additionally, stability, low solubility, negative effects existing drugs make them ineffective. Studies into alternative tactics tackle such tenacious diseases was sparked by anticancer antibacterial. Silver (Ag) gold (Au) nanoparticles (NPs) were created from Trichoderma saturnisporum, much productive fungal strain. Functional extracellular enzymes proteins carried out activities synthesis capping generated nano-metals. Characterization done on obtained Ag-NPs Au-NPs through UV-vis, FTIR, XRD, TEM, SEM. versus methicillin-sensitive Staphylococcus aureus (MSSA) methicillin-resistant (MRSA), Pseudomonas aeruginosa, Klebsiella pneumoniae, antibacterial assessed. In particular, effective against pathogenic bacteria than Au-NPs. Furthermore, antibiofilm study shown had activity Ag-NPs. Interestingly, applying DPPH procedure, these noble metallic NPs antioxidant activity, in which IC50 73.5 μg/mL 190.0 μg/mL, respectively. According cytotoxicity evaluation results, alteration cells as loss their typical shape, partial or complete monolayer, granulation, shrinking, cell rounding with normal Vero 693.68 661.24 Au-NPs, While cancer (Mcf7) 370.56 394.79 produced via green have potential employed medical industry beneficial nanocompounds.

Язык: Английский

---

Nanocomposite based on gold nanoparticles and carboxymethyl cellulose: Synthesis, characterization, antimicrobial, and anticancer activities

Journal of Drug Delivery Science and Technology, Год журнала: 2022, Номер 77, С. 103874 - 103874

Опубликована: Окт. 7, 2022

Язык: Английский

---

Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Lawsonia inermis Against Common Pathogens from Urinary Tract Infection

Applied Biochemistry and Biotechnology, Год журнала: 2023, Номер 196(1), С. 85 - 98

Опубликована: Апрель 26, 2023

Abstract New and creative methodologies for the fabrication of silver nanoparticles (Ag-NPs), which are exploited in a wide range consumer items, significant interest. Hence, this research emphasizes biological approach Ag-NPs through Egyptian henna leaves ( Lawsonia inermis Linn.) extracts analysis prepared Ag-NPs. Plant extract components were identified by gas chromatography mass spectrometry (GC-mass). The analyses carried out UV–visible (UV–Vis), X-ray diffraction (XRD), transmission electron microscope (TEM), scanning (SEM), Fourier transform infrared (FTIR) analysis. UV–Vis reveals that have maximum peak at 460 nm visible light. Structural characterization recorded peaks corresponded to Bragg’s diffractions nano-crystal, with average crystallite sizes varying from 28 60 nm. Antibacterial activities examined, it is observed all microorganisms very sensitive biologically synthesized

Язык: Английский

---

Green synthesized ZnO nanoparticles by Saccharomyces cerevisiae and their antibacterial activity and photocatalytic degradation

Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown

Опубликована: Сен. 15, 2023

Abstract Many research papers are currently being written about various methodologies for the green synthesis of ZnO nanoparticles. In this study, nanoparticles were prepared by method using baker’s yeast ( Saccharomyces cerevisiae ). The characterization produced involved utilization XRD, FTIR, SEM, and TEM. investigation assessment antimicrobial potential photocatalytic degradation efficacy synthesized materials through Eriochrome Black T (EBT). results indicate that exhibit a spherical morphology, exhibiting diameters ranging from 13.0 to 20.0nm, with an average particle size 15.0nm. against S. aureus ) gram-positive E. coli gram-negative bacteria was tested conduction zone inhibition (ZOI) minimum inhibitory concentration (MIC) tests. This focused on study photocatalytic-degradation EBT in presence ultraviolet light. experiments impact factors, such as pH levels, initial concentration, nanocatalyst dosage, observed efficiency. vitro ZOI MIC assay, it (NPs) exhibited greater , measuring 23.1 mm 0.625 μg/ml. contrast, effectiveness ZnO-NPs comparatively lower, indicated 17.0 1.250μg/ml. greatest elimination, which achieved 83.0% equilibrium, found employing 20.0mg NPs at 3.0, according activity results. synthetic powerful antibacterial agents effective may be used treatment wastewater.

Язык: Английский

---

Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Frontiers in Nanotechnology, Год журнала: 2023, Номер 5

Опубликована: Май 2, 2023

Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs several advantages over chemically ones eco-friendly synthesis regimen, sustainability, biocompatibility, diverse multifarious biomedical applications. Moreover, the superior cytocompatibility stability capping layer (MNPs), reduces like hood of toxicity side effects, making them a safer alternative traditional drug delivery methods. Among promising applications BMNPs, antibacterial activity, analytical sensing heavy metals, roles in food preservations been widely explored. In addition, imaging, also investigated for therapeutic activity such as antimicrobial efficacy against skin soft tissue nosocomial pathogens targeting cancer cells therapy. The present review bestows characterization techniques involved with MNPs compressive aspects biogenic using agricultural materials, which cost minimizes use hazardous chemicals. focuses on multifold including biomedical, analytical, preservation food, other consumable goods toxicological aspects.

Язык: Английский

---

Antimicrobial, Antibiofilm, and Anticancer Activities of Syzygium aromaticum Essential Oil Nanoemulsion

Molecules, Год журнала: 2023, Номер 28(15), С. 5812 - 5812

Опубликована: Авг. 1, 2023

In the current study, clove oil nanoemulsion (CL-nanoemulsion) and emulsion (CL-emulsion) were prepared through an ecofriendly method. The CL-nanoemulsion CL-emulsion characterized using dynamic light scattering (DLS) a transmission electron microscope (TEM), where results illustrated that droplets approximately 32.67 nm in size spherical shape, while 225.8 with shape. antibacterial activity of was carried out microbroth dilution Results revealed preferred had minimal MIC values between 0.31 5 mg/mL. antibiofilm efficacy against S. aureus significantly decreased development biofilm compared CL-emulsion. Furthermore, showed antifungal higher than Moreover, exhibited outstanding efficiency toward Candida albicans, Cryptococcus neoformans, Aspergillus brasiliensis, A. flavus, fumigatus MICs 12.5, 3.12, 0.78, 1.56, 1.56 mg/mL, respectively. Additionally, analyzed for its antineoplastic effects modified MTT assay evaluating apoptotic cytotoxic HepG2 MCF-7 cell lines. breast cancer cells lowest IC50 (3.4-fold) relative to Thus, induces apoptosis by inducing caspase-8 -9 suppressing VEGFR-2. conclusion, antibacterial, antifungal, as well anticancer properties, which can be used different biomedical applications after extensive studies vivo.

Язык: Английский

---

Multifunctional properties of silver and gold nanoparticles synthesis by Fusarium pseudonygamai

Biomass Conversion and Biorefinery, Год журнала: 2022, Номер 14(22), С. 28253 - 28270

Опубликована: Ноя. 11, 2022

Abstract The goal of the current work was to investigate antibacterial, antibiofilm, anticancer, and antioxidant opportunities silver gold nanoparticles (AgNPs AuNPs) synthesized utilizing a new fungus strain called Fusarium pseudonygamai TB-13c. With aid UV, HR-TEM, FTIR, SEM, XRD, NPs’ creation examined. For AgNPs AuNPs, mycosynthesized highest peak plasmon band seen at around 420 540 nm, respectively. ranged in size from 5 20 whereas AuNPs 8 60 nm. were spherical form. AgNPs, angles 38.42°, 44.56°, 64.66°, 77.75°; for 38.56°, 44.74°, 64.87°, 77.85°. antibacterial efficiency evaluated against Klebsiella pneumoniae , Pseudomonas aeruginosa methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant (MRSA). In particular, outperformed their ability combat pathogenic microorganisms. Furthermore, antibiofilm study that shown had activity more than AgNPs. Interestingly, applying DPPH procedure these noble metallic NPs activity, which IC 50 38.2 μg/ mL 180 AuNPs. modification cells evident cytotoxicity evaluation findings as change usual shape, partially or completely loss monolayer, granulation, shrinkage, cell rounding with normal vero 695.34 μg/mL 631.66 respectively, whilst cancer (Mcf7) 204.07 206.95 combined results show there is clear flexible biological use less toxic chemotherapeutic agents.

Язык: Английский

---

Biosynthesis MgO and ZnO nanoparticles using chitosan extracted from Pimelia Payraudi Latreille for antibacterial applications

World Journal of Microbiology and Biotechnology, Год журнала: 2022, Номер 39(1)

Опубликована: Ноя. 21, 2022

Язык: Английский

---

Electrochemical and optical-based systems for SARS-COV-2 and various pathogens assessment

Advances in Natural Sciences Nanoscience and Nanotechnology, Год журнала: 2023, Номер 14(3), С. 033001 - 033001

Опубликована: Авг. 17, 2023

Abstract A critical step in the process for preventing and identifying emergencies relating to health, safety, welfare is testing quick diagnosis of microbial pathogens. Due fast spread waterborne food borne infections society high costs associated with them, pathogen identification has emerged as one most difficult parts water sectors. Since turn century, pathogens have demonstrated enormous epidemiological pandemic potential. The emergence dissemination a novel virus potential endanger livelihoods well-being individuals worldwide. severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) coronavirus propagated almost every country on Earth had considerable negative influence economies communities. Despite improvements techniques viral diseases, all nations must now execute biosensing speedy, sensitive, focused, consistent manner order address pressing global issues. Hence, this review, we critically summarised recent advancement electrochemical well optical biosensors monitoring SARS-COV-2 various Then, began by providing technical overview cutting-edge strategies utilised combat diseases it, including utilisation point-of-care technology (POCT), artificial intelligence (AI), internet medical things (IoMT). This review article explores integration POC, IoMT, AI technologies context personal healthcare, focusing their expedite treatment conditions, ultimately leading improved patient outcomes. Subsequently, notion execution multiplex are presented enhance comprehension detecting multiple analytes. Finally, conclusions future directions been presented.

Язык: Английский

---