International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(21), С. 11563 - 11563
Опубликована: Окт. 28, 2024
The
use
of
metal
and
oxide
nanoparticles
is
frequently
regarded
as
a
potential
solution
to
the
issue
bacterial
antibiotic
resistance.
Among
proposed
range
with
antibacterial
properties,
copper
are
particular
interest.
Although
properties
have
been
known
for
considerable
period
time,
studies
on
effects
nanomaterials
respect
biological
systems
attracted
attention
in
recent
years.
This
review
presents
summary
nanoparticles,
mechanisms
by
which
effect
realized,
key
reported
methods
modifying
these
improve
their
activity.
A
comparative
analysis
effectiveness
presented
depending
type
microorganism,
shape
Gram
classification
bacteria
based
data
from
published
sources.
In
addition,
addresses
activities
including
antifungal
cytotoxic
well
“antioxidant”
According
conducted
literature
data,
it
can
be
concluded
that
significant
bacteriostatic
wide
microorganisms
and,
some
cases,
contribute
inhibition
fungal
growth.
At
same
sensitivity
Gram-positive
was
often
higher
than
Gram-negative
bacteria.
Archives of Microbiology,
Год журнала:
2023,
Номер
205(4)
Опубликована: Март 22, 2023
The
utilization
of
living
organisms
for
the
creation
inorganic
nanoscale
particles
is
a
potential
new
development
in
realm
biotechnology.
An
essential
milestone
nanotechnology
process
creating
dependable
and
environmentally
acceptable
metallic
nanoparticles.
Due
to
its
increasing
popularity
ease,
use
ambient
biological
resources
quickly
becoming
more
significant
this
field
study.
phrase
"green
nanotechnology"
has
gained
lot
attention
refers
variety
procedures
that
eliminate
or
do
away
with
hazardous
compounds
repair
environment.
Green
nanomaterials
can
be
used
biotechnological
sectors
such
as
medicine
biology,
well
food
textile
industries,
wastewater
treatment
agriculture
field.
construction
an
updated
level
knowledge
study
systems
might
support
revolutionize
nanoparticles
(NPs)
are
presented
article.
Applied Biochemistry and Biotechnology,
Год журнала:
2022,
Номер
195(2), С. 1158 - 1183
Опубликована: Ноя. 7, 2022
The
World
Health
Organization
(WHO)
reports
that
the
emergence
of
multidrug-resistant
and
slow
advent
novel
more
potent
antitumor
antimicrobial
chemotherapeutics
continue
to
be
highest
concern
for
human
health.
Additionally,
stability,
low
solubility,
negative
effects
existing
drugs
make
them
ineffective.
Studies
into
alternative
tactics
tackle
such
tenacious
diseases
was
sparked
by
anticancer
antibacterial.
Silver
(Ag)
gold
(Au)
nanoparticles
(NPs)
were
created
from
Trichoderma
saturnisporum,
much
productive
fungal
strain.
Functional
extracellular
enzymes
proteins
carried
out
activities
synthesis
capping
generated
nano-metals.
Characterization
done
on
obtained
Ag-NPs
Au-NPs
through
UV-vis,
FTIR,
XRD,
TEM,
SEM.
versus
methicillin-sensitive
Staphylococcus
aureus
(MSSA)
methicillin-resistant
(MRSA),
Pseudomonas
aeruginosa,
Klebsiella
pneumoniae,
antibacterial
assessed.
In
particular,
effective
against
pathogenic
bacteria
than
Au-NPs.
Furthermore,
antibiofilm
study
shown
had
activity
Ag-NPs.
Interestingly,
applying
DPPH
procedure,
these
noble
metallic
NPs
antioxidant
activity,
in
which
IC50
73.5
μg/mL
190.0
μg/mL,
respectively.
According
cytotoxicity
evaluation
results,
alteration
cells
as
loss
their
typical
shape,
partial
or
complete
monolayer,
granulation,
shrinking,
cell
rounding
with
normal
Vero
693.68
661.24
Au-NPs,
While
cancer
(Mcf7)
370.56
394.79
produced
via
green
have
potential
employed
medical
industry
beneficial
nanocompounds.
Applied Biochemistry and Biotechnology,
Год журнала:
2023,
Номер
196(1), С. 85 - 98
Опубликована: Апрель 26, 2023
Abstract
New
and
creative
methodologies
for
the
fabrication
of
silver
nanoparticles
(Ag-NPs),
which
are
exploited
in
a
wide
range
consumer
items,
significant
interest.
Hence,
this
research
emphasizes
biological
approach
Ag-NPs
through
Egyptian
henna
leaves
(
Lawsonia
inermis
Linn.)
extracts
analysis
prepared
Ag-NPs.
Plant
extract
components
were
identified
by
gas
chromatography
mass
spectrometry
(GC-mass).
The
analyses
carried
out
UV–visible
(UV–Vis),
X-ray
diffraction
(XRD),
transmission
electron
microscope
(TEM),
scanning
(SEM),
Fourier
transform
infrared
(FTIR)
analysis.
UV–Vis
reveals
that
have
maximum
peak
at
460
nm
visible
light.
Structural
characterization
recorded
peaks
corresponded
to
Bragg’s
diffractions
nano-crystal,
with
average
crystallite
sizes
varying
from
28
60
nm.
Antibacterial
activities
examined,
it
is
observed
all
microorganisms
very
sensitive
biologically
synthesized
Biomass Conversion and Biorefinery,
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 15, 2023
Abstract
Many
research
papers
are
currently
being
written
about
various
methodologies
for
the
green
synthesis
of
ZnO
nanoparticles.
In
this
study,
nanoparticles
were
prepared
by
method
using
baker’s
yeast
(
Saccharomyces
cerevisiae
).
The
characterization
produced
involved
utilization
XRD,
FTIR,
SEM,
and
TEM.
investigation
assessment
antimicrobial
potential
photocatalytic
degradation
efficacy
synthesized
materials
through
Eriochrome
Black
T
(EBT).
results
indicate
that
exhibit
a
spherical
morphology,
exhibiting
diameters
ranging
from
13.0
to
20.0nm,
with
an
average
particle
size
15.0nm.
against
S.
aureus
)
gram-positive
E.
coli
gram-negative
bacteria
was
tested
conduction
zone
inhibition
(ZOI)
minimum
inhibitory
concentration
(MIC)
tests.
This
focused
on
study
photocatalytic-degradation
EBT
in
presence
ultraviolet
light.
experiments
impact
factors,
such
as
pH
levels,
initial
concentration,
nanocatalyst
dosage,
observed
efficiency.
vitro
ZOI
MIC
assay,
it
(NPs)
exhibited
greater
,
measuring
23.1
mm
0.625
μg/ml.
contrast,
effectiveness
ZnO-NPs
comparatively
lower,
indicated
17.0
1.250μg/ml.
greatest
elimination,
which
achieved
83.0%
equilibrium,
found
employing
20.0mg
NPs
at
3.0,
according
activity
results.
synthetic
powerful
antibacterial
agents
effective
may
be
used
treatment
wastewater.
Frontiers in Nanotechnology,
Год журнала:
2023,
Номер
5
Опубликована: Май 2, 2023
Biogenic
metallic
nanoparticles
(BMNPs)
are
nanostructure
materials
synthesized
through
biological
processes
that
have
gained
significant
attention
due
to
their
small
size
and
high
surface
area-to-volume
ratio.
BMNPs
several
advantages
over
chemically
ones
eco-friendly
synthesis
regimen,
sustainability,
biocompatibility,
diverse
multifarious
biomedical
applications.
Moreover,
the
superior
cytocompatibility
stability
capping
layer
(MNPs),
reduces
like
hood
of
toxicity
side
effects,
making
them
a
safer
alternative
traditional
drug
delivery
methods.
Among
promising
applications
BMNPs,
antibacterial
activity,
analytical
sensing
heavy
metals,
roles
in
food
preservations
been
widely
explored.
In
addition,
imaging,
also
investigated
for
therapeutic
activity
such
as
antimicrobial
efficacy
against
skin
soft
tissue
nosocomial
pathogens
targeting
cancer
cells
therapy.
The
present
review
bestows
characterization
techniques
involved
with
MNPs
compressive
aspects
biogenic
using
agricultural
materials,
which
cost
minimizes
use
hazardous
chemicals.
focuses
on
multifold
including
biomedical,
analytical,
preservation
food,
other
consumable
goods
toxicological
aspects.
Molecules,
Год журнала:
2023,
Номер
28(15), С. 5812 - 5812
Опубликована: Авг. 1, 2023
In
the
current
study,
clove
oil
nanoemulsion
(CL-nanoemulsion)
and
emulsion
(CL-emulsion)
were
prepared
through
an
ecofriendly
method.
The
CL-nanoemulsion
CL-emulsion
characterized
using
dynamic
light
scattering
(DLS)
a
transmission
electron
microscope
(TEM),
where
results
illustrated
that
droplets
approximately
32.67
nm
in
size
spherical
shape,
while
225.8
with
shape.
antibacterial
activity
of
was
carried
out
microbroth
dilution
Results
revealed
preferred
had
minimal
MIC
values
between
0.31
5
mg/mL.
antibiofilm
efficacy
against
S.
aureus
significantly
decreased
development
biofilm
compared
CL-emulsion.
Furthermore,
showed
antifungal
higher
than
Moreover,
exhibited
outstanding
efficiency
toward
Candida
albicans,
Cryptococcus
neoformans,
Aspergillus
brasiliensis,
A.
flavus,
fumigatus
MICs
12.5,
3.12,
0.78,
1.56,
1.56
mg/mL,
respectively.
Additionally,
analyzed
for
its
antineoplastic
effects
modified
MTT
assay
evaluating
apoptotic
cytotoxic
HepG2
MCF-7
cell
lines.
breast
cancer
cells
lowest
IC50
(3.4-fold)
relative
to
Thus,
induces
apoptosis
by
inducing
caspase-8
-9
suppressing
VEGFR-2.
conclusion,
antibacterial,
antifungal,
as
well
anticancer
properties,
which
can
be
used
different
biomedical
applications
after
extensive
studies
vivo.
Biomass Conversion and Biorefinery,
Год журнала:
2022,
Номер
14(22), С. 28253 - 28270
Опубликована: Ноя. 11, 2022
Abstract
The
goal
of
the
current
work
was
to
investigate
antibacterial,
antibiofilm,
anticancer,
and
antioxidant
opportunities
silver
gold
nanoparticles
(AgNPs
AuNPs)
synthesized
utilizing
a
new
fungus
strain
called
Fusarium
pseudonygamai
TB-13c.
With
aid
UV,
HR-TEM,
FTIR,
SEM,
XRD,
NPs’
creation
examined.
For
AgNPs
AuNPs,
mycosynthesized
highest
peak
plasmon
band
seen
at
around
420
540
nm,
respectively.
ranged
in
size
from
5
20
whereas
AuNPs
8
60
nm.
were
spherical
form.
AgNPs,
angles
38.42°,
44.56°,
64.66°,
77.75°;
for
38.56°,
44.74°,
64.87°,
77.85°.
antibacterial
efficiency
evaluated
against
Klebsiella
pneumoniae
,
Pseudomonas
aeruginosa
methicillin-sensitive
Staphylococcus
aureus
(MSSA),
methicillin-resistant
(MRSA).
In
particular,
outperformed
their
ability
combat
pathogenic
microorganisms.
Furthermore,
antibiofilm
study
that
shown
had
activity
more
than
AgNPs.
Interestingly,
applying
DPPH
procedure
these
noble
metallic
NPs
activity,
which
IC
50
38.2
μg/
mL
180
AuNPs.
modification
cells
evident
cytotoxicity
evaluation
findings
as
change
usual
shape,
partially
or
completely
loss
monolayer,
granulation,
shrinkage,
cell
rounding
with
normal
vero
695.34
μg/mL
631.66
respectively,
whilst
cancer
(Mcf7)
204.07
206.95
combined
results
show
there
is
clear
flexible
biological
use
less
toxic
chemotherapeutic
agents.
Advances in Natural Sciences Nanoscience and Nanotechnology,
Год журнала:
2023,
Номер
14(3), С. 033001 - 033001
Опубликована: Авг. 17, 2023
Abstract
A
critical
step
in
the
process
for
preventing
and
identifying
emergencies
relating
to
health,
safety,
welfare
is
testing
quick
diagnosis
of
microbial
pathogens.
Due
fast
spread
waterborne
food
borne
infections
society
high
costs
associated
with
them,
pathogen
identification
has
emerged
as
one
most
difficult
parts
water
sectors.
Since
turn
century,
pathogens
have
demonstrated
enormous
epidemiological
pandemic
potential.
The
emergence
dissemination
a
novel
virus
potential
endanger
livelihoods
well-being
individuals
worldwide.
severe
acute
respiratory
syndrome-coronavirus-2
(SARS-COV-2)
coronavirus
propagated
almost
every
country
on
Earth
had
considerable
negative
influence
economies
communities.
Despite
improvements
techniques
viral
diseases,
all
nations
must
now
execute
biosensing
speedy,
sensitive,
focused,
consistent
manner
order
address
pressing
global
issues.
Hence,
this
review,
we
critically
summarised
recent
advancement
electrochemical
well
optical
biosensors
monitoring
SARS-COV-2
various
Then,
began
by
providing
technical
overview
cutting-edge
strategies
utilised
combat
diseases
it,
including
utilisation
point-of-care
technology
(POCT),
artificial
intelligence
(AI),
internet
medical
things
(IoMT).
This
review
article
explores
integration
POC,
IoMT,
AI
technologies
context
personal
healthcare,
focusing
their
expedite
treatment
conditions,
ultimately
leading
improved
patient
outcomes.
Subsequently,
notion
execution
multiplex
are
presented
enhance
comprehension
detecting
multiple
analytes.
Finally,
conclusions
future
directions
been
presented.