Critical Reviews in Microbiology,
Год журнала:
2025,
Номер
unknown, С. 1 - 23
Опубликована: Май 5, 2025
The
growing
demand
for
nanomedicine
and
its
potentially
diverse
biological
function
required
the
investigation
of
raw
materials
fabricating
nanomaterial.
Current
developments
have
emphasized
implementation
green
chemistry
to
develop
metal-oxide
metal
nanoparticles.
Endophytic
fungi
emerged
as
a
potential
reservoir
bioactive
compounds
exemplified
by
unique
structures
influential
antibacterial
properties.
Over
past
decade,
substantial
progress
has
been
achieved
in
uncovering
profiling
these
valuable
compounds.
These
endophytic
fungi-derived
chemicals
applications
various
Nanoparticle
synthesis
from
derived
fungi,
be
it
whole
extracts
or
pure
components,
owing
their
accessibility,
cost-effectiveness
fabrication,
material-tissue
compatibility,
modest
cytotoxicity
toward
higher
organism
cells.
Nanoparticles
utilized
treat
diseases,
including
those
caused
bacterial,
viral,
fungal
pathogens.
present
review
provides
comprehensive
discussion
mechanistic
insight
into
application
fungi-bioinspired
nanoparticles
therapeutic
agents
control
microbial
infection.
underlying
action
mechanism
involved
antimicrobial
also
discussed.
highlights
attributes
that
may
significantly
benefit
future
researchers
Abstract
Background
and
objectives
Microbial
cells
capability
to
tolerate
the
effect
of
various
antimicrobial
classes
represent
a
major
worldwide
health
concern.
The
flexible
multi-components
nanocomposites
have
enhanced
physicochemical
characters
with
several
improved
properties.
Thus,
different
biological
activities
biosynthesized
starch/silver-selenium
nanocomposite
(St/Ag-Se
NC)
were
assessed.
Methodology
St/Ag-Se
NC
was
using
Cladosporium
cladosporioides
CBS
174.62
(
C.
)
strain.
shape
average
particle
size
investigated
scanning
electron
microscope
(SEM)
high-resolution
transmission
(HR-TEM),
respectively.
On
other
hand,
on
two
cancer
cell
lines
red
blood
(RBCs)
evaluated
its
hydrogen
peroxide
(H
2
O
scavenging
Moreover,
effects
microbial
species
in
both
planktonic
biofilm
growth
forms
examined.
Results
successfully
oval
spherical
mean
diameter
67.87
nm
as
confirmed
by
HR-TEM
analysis.
showed
promising
anticancer
activity
toward
human
colorectal
carcinoma
(HCT-116)
breast
(MCF-7)
where
IC
50
21.37
19.98
µg/ml,
Similarly,
little
RBCs
observed
low
concentration.
As
well,
highest
H
(42.84%)
recorded
at
concentration
mg/ml.
Additionally,
Staphylococcus
epidermidis
S.
ATCC
12,228
Candida
albicans
10,231
highly
affected
bacterial
fungal
strains
minimum
inhibitory
concentrations
(MICs)
18.75
noticeable
dependent.
A
high
suppression
percentage,
87.5%
68.05%,
aureus
when
exposed
1
mg/ml
0.5
mg/ml,
Conclusion
excellent
antioxidant
activity,
haemocompatibility,
anti-proliferative
concentrations.
Also,
it
exhibited
antibiofilm
activities.
Abstract
Scientists
know
very
little
about
the
mechanisms
underlying
fish
skin
mucus,
despite
fact
that
it
is
a
component
of
immune
system.
Fish
mucus
an
important
defence
against
invasive
infections.
Recently,
and
its
are
gaining
interest
among
immunologists.
Characterization
was
done
on
obtained
silver
nanoparticles
Ag
combined
with
Clarias
gariepinus
catfish
epidermal
proteins
(EMP-Ag-NPs)
through
UV–vis,
FTIR,
XRD,
TEM,
SEM.
Ag-NPs
ranged
in
size
from
4
to
20
nm,
spherical
form
angles
were
38.10°,
44.20°,
64.40°,
77.20°,
Where
wavelength
change
after
formation
EMP-Ag-NPs
as
indicate
dark
brown,
broad
band
recorded
at
391
nm.
Additionally,
antimicrobial,
antibiofilm
anticancer
activities
assessed.
The
present
results
demonstrate
high
activity
unicellular
fungi
C.
albicans
,
followed
by
E.
faecalis
.
Antibiofilm
showed
strong
both
S.
aureus
P.
aeruginosa
pathogens
dose-dependent
manner,
without
affecting
planktonic
cell
growth.
Also,
cytotoxicity
effect
investigated
normal
cells
(Vero),
breast
cancer
(Mcf7)
hepatic
carcinoma
(HepG2)
lines
concentrations
(200–6.25
µg/mL)
current
highly
100,
5
25
µg/mL
exhibited
rounding,
shrinkage,
deformation
granulation
Mcf7
HepG2
IC50
19.34
31.16
respectively
while
Vero
appeared
rounded
concentration
50
shape
25,
12.5
6.25
µg/ml
35.85
µg/mL.
This
study
evidence
potential
efficacy
biologically
generated
substitute
medicinal
agent
harmful
microorganisms.
Furthermore,
highlights
their
inhibitory
lines.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 4137 - 4162
Опубликована: Май 1, 2024
Background:
In
the
current
scenario,
synthesis
of
nanoparticles
(NPs)
using
environmentally
benign
methods
has
gained
significant
attention
due
to
their
facile
processes,
cost-effectiveness,
and
eco-friendly
nature.
Methods:
present
study,
copper
oxide
(CuO
NPs)
were
synthesized
aqueous
extract
Coelastrella
terrestris
algae
as
a
reducing,
stabilizing,
capping
agent.
The
CuO
NPs
characterized
by
X-ray
diffraction
(XRD),
UV-visible
spectroscopy
(UV-Vis),
Fourier
transform
infrared
(FTIR),
dynamic
light
scattering
(DLS),
field
emission
scanning
electron
microscopy
(FE-SEM)
coupled
with
energy-dispersive
(EDS).
Results:
XRD
investigation
revealed
that
biosynthesized
nanocrystalline
high-phase
purity
size
in
range
4.26
nm
28.51
nm.
FTIR
spectra
confirmed
existence
secondary
metabolites
on
surface
NPs,
characteristic
Cu–O
vibrations
being
identified
around
600
cm
−
1
,
496
440
.
FE-SEM
images
predicted
enhancement
algal
amount
converted
flattened
rice-like
structures
into
flower
petal-like
structures.
Furthermore,
degradation
ability
was
investigated
against
Amido
black
10B
(AB10B)
dye.
results
displayed
optimal
efficacy
AB10B
dye
94.19%,
obtained
at
6
pH,
50
ppm
concentration
dye,
0.05
g
dosage
90
min
pseudo-first-order
rate
constant
0.0296
CuO-1
through
exhibited
notable
antibacterial
S.
aureus
zone
inhibition
(ZOI)
22
mm
P.
aeruginosa
ZOI
17
mm.
Conclusion:
Based
findings
this
it
can
be
concluded
utilizing
for
presents
promising
solution
addressing
environmental
contamination.
Keywords:
green
synthesis,
photocatalysis,
activity,
wastewater
treatment
Green Processing and Synthesis,
Год журнала:
2024,
Номер
13(1)
Опубликована: Янв. 1, 2024
Abstract
Some
of
the
significant
globally
prevalent
vector-borne
illnesses
are
caused
by
Culex
pipiens
.
Synthetic
pesticides
have
been
widely
utilized
to
eradicate
C.
,
which
has
led
a
number
health
risks
for
people,
insect
resistance,
and
environmental
contamination.
Alternative
strategies
therefore
vitally
needed.
In
current
investigation,
Trichoderma
viride
fungal
culture
filtrate
was
used
create
selenium
silver
nanoparticles
(SeNPs
AgNPs,
respectively)
test
them
on
larvae
in
their
fourth
instar
stage.
The
death
rate
increased
significantly
when
SeNP
AgNP
concentrations
increased,
according
results.
SeNPs
AgNPs
affected
developmental
detoxification
enzymes
at
24
h
after
being
treated
with
sublethal
concentration
tested
NPs.
As
result
insecticidal
effect
larvae,
considered
effective
promising
larvicidal
agents.
Heliyon,
Год журнала:
2024,
Номер
10(9), С. e29726 - e29726
Опубликована: Апрель 16, 2024
Hybrid
nanostructures
exhibit
a
synergistic
combination
of
features
derived
from
their
individual
components,
showcasing
novel
characteristics
resulting
distinctive
structure
and
chemical/physical
properties.
Surface
modifiers
play
pivotal
role
in
shaping
INPs'
primary
attributes,
influencing
physicochemical
properties,
stability,
functional
applications.
Among
these
modifiers,
dendrimers
have
gained
attention
as
highly
effective
multifunctional
agents
for
INPs,
owing
to
unique
structural
qualities,
dendritic
effects,
Dendrimers
can
be
seamlessly
integrated
with
diverse
inorganic
nanostructures,
including
metal
NPs,
carbon
silica
QDs.
Two
viable
approaches
achieving
this
integration
involve
either
growing
or
grafting
dendrimers,
nanostructure-cored
dendrimers.
The
initial
step
involves
functionalizing
the
nanostructures'
surface,
followed
by
generation
through
stepwise
growth
attachment
pre-synthesized
dendrimer
branches.
This
hybridization
imparts
superior
qualities
structure,
biocompatibility,
solubility,
high
cargo
loading
capacity,
substantial
functionalization
potential.
Combining
properties
those
nanostructure
cores
creates
system
suitable
applications
such
theranostics,
bio-sensing,
component
isolation,
chemotherapy,
cargo-carrying
review
summarizes
recent
developments,
specific
focus
on
last
five
years,
within
realm
It
delves
into
INPs
explores
potential
INP-cored
biomedical