An overview of the relationship between melatonin and drug resistance in cancers DOI
Ahmad Fazilat,

Salomeh Roshani,

Fatemeh Mortazavi Moghadam

и другие.

Hormone Molecular Biology and Clinical Investigation, Год журнала: 2025, Номер unknown

Опубликована: Май 21, 2025

Abstract The most common methods of treating cancer are surgery, chemotherapy, and radiotherapy. However, given that some cancers not operable, the best method is chemotherapy Over time, people become resistant to drugs, increasing dose drug leads damage normal cells. In this article, various sources such as Google Scholar, PubMed, Semantic Scholar were used, articles between 1997 2025 relevant our topic selected. Various factors involved in resistance. Melatonin a hormone has roles body. One its important functions regulating circadian rhythm sleep anti-inflammatory antioxidant properties. According studies, melatonin plays role treatment diseases cancers. include anti-apoptotic, anti-angiogenic, anti-migratory effects, well resistance cell cycle regulation. As mentioned, one main reasons for failure resistance, been proven. Therefore, study, goal investigate mechanisms through which different types cancer.

Язык: Английский

Cytokine-mediated regulation of immune cell metabolic pathways in the tumor microenvironment DOI

Alireza Soleimani Mamalo,

Mohammad Reza Pashaei, Mohammad Valilo

и другие.

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 12, 2025

Язык: Английский

Процитировано

0

Exploring Target Genes in the miRNA-mRNA Regulatory Network of Lung Adenocarcinoma Based on Bioinformatics DOI Open Access

刘梦 段

Journal of Clinical Personalized Medicine, Год журнала: 2025, Номер 04(02), С. 1196 - 1204

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Molecular mechanisms and clinical significance of perineural invasion in malignancies: the pivotal role of tumor-associated Schwann cells in cancer progression and metastasis DOI

Noura A. A. Ebrahim,

Soliman M. A. Soliman,

Maha Othman

и другие.

Medical Oncology, Год журнала: 2025, Номер 42(5)

Опубликована: Апрель 21, 2025

Язык: Английский

Процитировано

0

An overview of the relationship between melatonin and drug resistance in cancers DOI
Ahmad Fazilat,

Salomeh Roshani,

Fatemeh Mortazavi Moghadam

и другие.

Hormone Molecular Biology and Clinical Investigation, Год журнала: 2025, Номер unknown

Опубликована: Май 21, 2025

Abstract The most common methods of treating cancer are surgery, chemotherapy, and radiotherapy. However, given that some cancers not operable, the best method is chemotherapy Over time, people become resistant to drugs, increasing dose drug leads damage normal cells. In this article, various sources such as Google Scholar, PubMed, Semantic Scholar were used, articles between 1997 2025 relevant our topic selected. Various factors involved in resistance. Melatonin a hormone has roles body. One its important functions regulating circadian rhythm sleep anti-inflammatory antioxidant properties. According studies, melatonin plays role treatment diseases cancers. include anti-apoptotic, anti-angiogenic, anti-migratory effects, well resistance cell cycle regulation. As mentioned, one main reasons for failure resistance, been proven. Therefore, study, goal investigate mechanisms through which different types cancer.

Язык: Английский

Процитировано

0