An overview of the relationship between melatonin and drug resistance in cancers DOI
Ahmad Fazilat,

Salomeh Roshani,

Fatemeh Mortazavi Moghadam

et al.

Hormone Molecular Biology and Clinical Investigation, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Abstract The most common methods of treating cancer are surgery, chemotherapy, and radiotherapy. However, given that some cancers not operable, the best method is chemotherapy Over time, people become resistant to drugs, increasing dose drug leads damage normal cells. In this article, various sources such as Google Scholar, PubMed, Semantic Scholar were used, articles between 1997 2025 relevant our topic selected. Various factors involved in resistance. Melatonin a hormone has roles body. One its important functions regulating circadian rhythm sleep anti-inflammatory antioxidant properties. According studies, melatonin plays role treatment diseases cancers. include anti-apoptotic, anti-angiogenic, anti-migratory effects, well resistance cell cycle regulation. As mentioned, one main reasons for failure resistance, been proven. Therefore, study, goal investigate mechanisms through which different types cancer.

Language: Английский

Molecular mechanisms and clinical significance of perineural invasion in malignancies: the pivotal role of tumor-associated Schwann cells in cancer progression and metastasis DOI

Noura A. A. Ebrahim,

Soliman M. A. Soliman,

Maha Othman

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(5)

Published: April 21, 2025

Language: Английский

Citations

1
Cytokine-mediated regulation of immune cell metabolic pathways in the tumor microenvironment DOI

Alireza Soleimani Mamalo,

Mohammad Reza Pashaei, Mohammad Valilo

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

Language: Английский

Citations

0
Exploring Target Genes in the miRNA-mRNA Regulatory Network of Lung Adenocarcinoma Based on Bioinformatics DOI Open Access

刘梦 段

Journal of Clinical Personalized Medicine, Journal Year: 2025, Volume and Issue: 04(02), P. 1196 - 1204

Published: Jan. 1, 2025

Language: Английский

Citations

0
An overview of the relationship between melatonin and drug resistance in cancers DOI
Ahmad Fazilat,

Salomeh Roshani,

Fatemeh Mortazavi Moghadam

et al.

Hormone Molecular Biology and Clinical Investigation, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Abstract The most common methods of treating cancer are surgery, chemotherapy, and radiotherapy. However, given that some cancers not operable, the best method is chemotherapy Over time, people become resistant to drugs, increasing dose drug leads damage normal cells. In this article, various sources such as Google Scholar, PubMed, Semantic Scholar were used, articles between 1997 2025 relevant our topic selected. Various factors involved in resistance. Melatonin a hormone has roles body. One its important functions regulating circadian rhythm sleep anti-inflammatory antioxidant properties. According studies, melatonin plays role treatment diseases cancers. include anti-apoptotic, anti-angiogenic, anti-migratory effects, well resistance cell cycle regulation. As mentioned, one main reasons for failure resistance, been proven. Therefore, study, goal investigate mechanisms through which different types cancer.

Language: Английский

Citations

0