Concussion and the Autonomic, Immune, and Endocrine Systems: An Introduction to the Field and a Treatment Framework for Persisting Symptoms
Journal of Personalized Medicine,
Год журнала:
2025,
Номер
15(1), С. 33 - 33
Опубликована: Янв. 17, 2025
A
significant
proportion
of
patients
who
sustain
a
concussion/mild
traumatic
brain
injury
endorse
persisting,
lingering
symptoms.
The
symptoms
associated
with
concussion
are
nonspecific,
and
many
other
medical
conditions
present
similar
Medical
that
overlap
symptomatically
include
anxiety,
depression,
insomnia,
chronic
pain,
fatigue,
fibromyalgia,
cervical
strain
injuries.
One
the
factors
may
account
for
these
similarities
is
all
disturbances
in
optimal
functioning
autonomic
nervous
system
its
intricate
interactions
endocrine
immune
system—the
three
primary
regulatory
systems
body.
When
clinicians
working
presenting
persisting
after
concussion,
evidence-based
treatment
options
drawn
from
literature
limited.
We
framework
assessment
following
based
on
available
evidence
(treatment
trials),
neuroanatomical
principles
(research
into
physiology
concussion),
clinical
judgment.
review
research
supporting
premise
behavioral
interventions
designed
to
stabilize
optimize
body
have
potential
reduce
improve
patients.
Foundational
rehabilitation
strategies
areas
sleep
stabilization,
fatigue
management,
physical
exercise,
nutrition,
relaxation
protocols,
activation
outlined
along
practical
implementing
intervention
modules
Язык: Английский
Exploring the cognitive-enhancing effects of Ocimum gratissimum: an ethnopharmacological and phytochemical review
Discover Plants.,
Год журнала:
2025,
Номер
2(1)
Опубликована: Март 12, 2025
Язык: Английский
Disruption in the human microbiome causing behavioural changes in bipolar disorder
International review of neurobiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
The gut-brain axis in traumatic brain Injury: Literature review
Journal of Clinical Neuroscience,
Год журнала:
2025,
Номер
136, С. 111258 - 111258
Опубликована: Апрель 17, 2025
Язык: Английский
Quercetin prevents single prolonged stress-induced posttraumatic stress disorder and neurochemical changes via antioxidant, antiinflammatory and antiapoptotic mechanisms in rats
Neuroscience,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
Язык: Английский
Gut Microbiota and Neuroinflammation: An Interconnected Nexus of Health and Neurodegenerative Disease
OBM Neurobiology,
Год журнала:
2024,
Номер
08(04), С. 1 - 28
Опубликована: Ноя. 20, 2024
The
gut
microbiota,
a
complex
ecosystem
of
billions
microorganisms
in
the
human
digestive
tract,
plays
crucial
role
maintaining
health.
Recent
studies
have
highlighted
bidirectional
communication
pathway
called
gut-brain
axis
between
and
brain.
This
is
significantly
influenced
by
microbiota
its
interactions
with
immune
system,
which
can
affect
brain
function
contribute
to
inflammation.
study
aims
provide
comprehensive
overview
relationship
neuroinflammation,
focusing
on
underlying
mechanisms
implications
for
neurological
disorders.
A
thorough
literature
review
was
conducted,
examining
impact
this
interaction,
potential
therapeutic
applications.
modulates
neuroinflammation
through
various
pathways,
including
producing
short-chain
fatty
acids
(SCFAs),
modulating
regulating
nervous
system.
Dysbiosis,
characterized
an
imbalance
composition,
has
been
associated
increased
risk
conditions.
Interventions
such
as
probiotics,
prebiotics,
fecal
transplantation
show
promise
treating
neuroinflammation.
Understanding
pivotal
essential
developing
novel
strategies
prevent
manage
diseases.
Further
research
needed
elucidate
involved,
identify
specific
profiles
different
disorders,
optimize
personalized
therapies
based
microbiome
modulation.
Язык: Английский