PEG-mediated synthesis of naphthoquinone/coumarin fused dihydropyridine derivatives
Tetrahedron,
Год журнала:
2024,
Номер
160, С. 134025 - 134025
Опубликована: Май 7, 2024
Язык: Английский
Multicomponent synthesis of 3-(1H-indol-3-yl)-2-phenyl-1H-benzo[f]indole-4,9-dione derivatives
Darakshan,
Ujjain Chaurasia,
Aatka Mehar
и другие.
Molecular Diversity,
Год журнала:
2024,
Номер
unknown
Опубликована: Июнь 5, 2024
Язык: Английский
Efficient, Concise, and Chemoselective Synthesis of 1H‐Benzo[f]indole‐4,9‐dione with 4‐Hydroxycoumarin Substituent via a One‐Pot Three‐Component Reaction
ChemistrySelect,
Год журнала:
2023,
Номер
8(48)
Опубликована: Дек. 19, 2023
Abstract
Extensive
studies
on
the
biological
activities
of
several
quinone‐fused
heterocycles
have
confirmed
their
outstanding
antitumor
activity.
Therefore,
a
new
family
1
H
‐benzo[
f
]indole‐4,9‐dione
derivatives
with
4‐hydroxycoumarin
substitution
was
prepared
by
high‐yield,
one‐pot,
concise
three‐component
reaction
between
arylglyoxals,
4‐hydroxycoumarin,
and
2‐aminonaphthalene‐1,4‐dione
under
reflux
in
EtOH.
This
efficient
protocol
showed
chemoselectivity
addition
to
facile
operation
procedure
easy
purification.
Язык: Английский
A Detailed Review on the Synthesis and Mechanistic Study of Pyrrole Fused Quinone/Naphthoquinone
ChemistrySelect,
Год журнала:
2024,
Номер
9(46)
Опубликована: Дек. 1, 2024
Abstract
This
review
article
intends
to
explore
the
versatility
in
formation
of
pyrrole‐fused
quinone/naphthoquinone
derivatives
described
literature
from
2008
2024.
It
deals
with
multitude
paths
its
synthesis
a
variety
precursors
using
both
metal‐
and
metal‐free
catalytic
systems
their
potential
applications.
also
documented
several
bioactive
cores
accommodating
indoloquinone
analog.
Noteworthy,
mitomycin
A
acts
as
excellent
medicine
for
cancer
treatment
analog
EO‐9
is
under
clinical
trial.
Here
we
present
natural
products
zyzzyanone
A,
murrayaquinones
B
indolequinone‐based
naloxone
prodrugs
exiguamine
(NQO1)‐targeted
hypoxia
specific
activation,
antibiotic
uthamycin
analog,
indolequinone
fused
ursolic
acid
(a
triterpenoid
rich
many
Chinese
medicines),
which
vital
scaffold
preparation
novel
anticancer
agent.
Indoloquinone‐fused
medicines)
Recent
two
cyanobacterial
metabolites
Calothrixins
has
been
documented.
discusses
intermediate,
where
lymphostin
alkaloid
can
be
developed.
Lamellarin
D
product
easily
prepared
by
developed
strategy.
Язык: Английский