Antibacterial and Anti-virulence Properties of Cell-free Supernatant from a Mixture of Limosilactobacillus fermentum Strains Against Enterotoxigenic Escherichia coli
Probiotics and Antimicrobial Proteins,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
Язык: Английский
Impact of a Limosilactobacillus fermentum, Quercetin, and Resveratrol Nutraceutical on Fecal Microbiota Composition and Metabolic Activity in Healthy and Hypertensive Subjects
Foods,
Год журнала:
2025,
Номер
14(6), С. 986 - 986
Опубликована: Март 14, 2025
A
promising
strategy
to
improve
the
gut
microbiome
in
hypertension
is
target
microbiota.
This
study
evaluated
effects
of
a
potential
nutraceutical
product
composed
three
strains
Limosilactobacillus
(L.)
fermentum,
quercetin,
and
resveratrol
on
intestinal
healthy
hypertensive
subjects.
The
consisting
L.
fermentum
139,
263
296,
fructooligosaccharides
(200
mg),
quercetin
(160
(150
mg)
(LfQR)
was
added
vitro
fecal
fermentation
process
occurring
for
48
h.
Fecal
samples
subjects
were
allocated
into
four
groups:
(i)
controls
(CTL);
(ii)
with
addition
LfQR
(CTL
+
LfQR);
(iii)
(HTN)
subjects;
(iv)
(HTN
LfQR).
diversity
composition
microbiota
production
microbial
metabolites
evaluated.
CTL
HTN
groups
exhibited
distinct
composition,
as
shown
by
β-diversity
assessment.
potentially
nutraceutical-modulated
similar
between
groups,
suggesting
after
addition.
increased
relative
abundance
Enterobacteriaceae
group
that
Lachnospiraceae
group.
media
showed
higher
levels
sugars
(maltose,
fructose,
glucose),
lactic
acid,
ethanol,
succinic
acetic
acid
compared
media.
Although
results
are
heterogeneous
media,
it
demonstrated
formulation
can
modulate
its
metabolic
activity.
Язык: Английский
Exploring the Potential of Novel Animal-Origin Probiotics as Key Players in One Health: Opportunities and Challenges
Zofia Gorzelanna,
Aleksandra Mamrot,
Daria Będkowska
и другие.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(11), С. 5143 - 5143
Опубликована: Май 27, 2025
Probiotics
play
a
critical
role
in
promoting
the
health
of
both
humans
and
animals,
with
growing
interest
potential
animal-derived
strains.
Safety
efficacy
assessments
are
crucial,
rigorous
testing
required
to
ensure
absence
harmful
effects.
The
benefits
probiotic
strains
include
improved
digestion,
balanced
microbiota,
behavioral
impact,
reduced
inflammation,
minimized
risk
infections.
animal
origin
show
promise
as
complementary
or
alternative
options
antibiotics,
applications
veterinary
human
medicine.
While
promising,
usage
probiotics
requires
careful
evaluation
safety
regulatory
aspects.
This
research
underscores
their
for
across
species
contributing
future
therapeutic
approaches.
Язык: Английский
Function of Yogurt Fermented with the Lactococcus lactis 11/19-B1 Strain in Improving the Lipid Profile and Intestinal Microbiome in Hemodialysis Patients
Nutrients,
Год журнала:
2025,
Номер
17(11), С. 1931 - 1931
Опубликована: Июнь 4, 2025
Background/Objectives:
The
number
of
chronic
kidney
disease
(CKD)
patients
is
increasing
in
Japan,
and
this
population
at
high
risk
death
from
cardiovascular
cerebrovascular
diseases.
Therefore,
prevention
arteriosclerosis
as
a
common
underlying
cause
these
diseases
required.
In
study,
we
examined
whether
11/19-B1
yogurt,
which
has
been
proven
to
reduce
serum
low-density
lipoprotein
(LDL)
levels,
can
decrease
the
levels
indoxylsulfate
trimethylamine-N-oxide
(TMAO),
are
produced
by
intestinal
microbiota
known
arteriosclerosis,
through
improving
dysbiosis
hemodialysis
patients.
Methods:
Nineteen
dialysis
consumed
50
g
yogurt
daily
for
8
weeks,
changes
lipid
profile
uremic
toxin
microbiome,
well
frequency
bowel
movement
stool
characteristics
were
observed.
Results:
results
demonstrated
that
an
intake
decreased
LDL
99.3
88.5
(p
=
0.049)
seven
nine
subjects
with
previously
concentrations,
improved
estimated
Bristle
score,
although
HDL
no
beneficial
effect
on
TMAO
was
Conclusions:
These
may
suggest
ingestion
provides
preventative
against
progression
atherosclerosis
renal
dysfunction.
Язык: Английский