Innovation in Aging,
Год журнала:
2023,
Номер
7(9)
Опубликована: Окт. 13, 2023
Physical
resilience
(PR)
is
recognized
as
the
ability
to
recover
from
adverse
effects
of
a
stressor.
However,
there
lack
consensus
on
how
optimally
measure
PR
in
older
adults
general.
We
aimed
using
residuals
regression
analyses
and
investigated
its
association
with
outcomes
adults.A
total
6
508
were
included
National
Health
Aging
Trends
Study,
which
was
population-based
prospective
cohort
study.
assessed
residual
methods
linear
model
regressing
short
physical
performance
battery
clinical
diseases,
age,
sex,
race/ethnicity,
health
condition.
Adverse
all-cause
mortality,
falls,
overnight
hospitalization.The
mean
age
77.48
(7.84)
years.
Increased
associated
lower
risk
mortality
(hazard
ratio
[HR]
=
0.85,
95%
confidence
interval
[CI]:
0.83-0.87).
Compared
participants
reduced
PR,
those
normal
had
for
(HR
0.51,
CI:
0.46-0.56).
Specifically,
restricted
cubic
spline
revealed
dose-response
relationship
between
(p-overall
<
.0001,
p-nonlinear
.011).
Additionally,
we
also
found
significant
associations
increased
risks
falls
0.98,
0.96-0.99)
hospitalization
0.97-1.00).PR,
measured
by
methods,
robustly
independently
hospitalization.
Our
findings
provide
evidence
that
this
approach
may
be
simple
feasible
strategy
assess
PR.
Frontiers in Aging Neuroscience,
Год журнала:
2025,
Номер
17
Опубликована: Март 19, 2025
The
global
extension
of
human
lifespan
has
intensified
the
focus
on
aging,
yet
its
underlying
mechanisms
remain
inadequately
understood.
article
highlights
aspects
genetic
susceptibility
to
impaired
brain
bioenergetics,
trends
in
age-related
gene
expression
related
neuroinflammation
and
senescence,
impact
stem
cell
exhaustion
quiescence
accelerated
aging.
We
also
review
accumulation
senescent
cells,
mitochondrial
dysfunction,
metabolic
disturbances
as
central
pathological
processes
emphasizing
how
these
factors
contribute
inflammation
disrupt
cellular
competition
defining
aging
trajectory.
Furthermore,
we
discuss
emerging
therapeutic
strategies
future
potential
integrating
advanced
technologies
refine
assessments.
combination
several
methods
including
analysis,
neuroimaging
techniques,
cognitive
tests
digital
twins,
offer
a
novel
approach
by
simulating
monitoring
individual
health
trajectories,
thereby
providing
more
accurate
personalized
insights.
Conclusively,
estimation
trajectories
is
crucial
for
understanding
managing
processes,
potentially
transforming
preventive
improve
outcomes
populations.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Апрель 1, 2025
The
number
of
older
adults
is
growing
rapidly
worldwide,
and
many
surgical
diseases
are
prevalent
in
this
population.
Resilience,
the
ability
to
adapt
positively
adversity,
remains
a
multisystemic
process
with
no
standardized
objective
measurement
methods.
aim
study
was
identify
association
between
resilience
components
frailty,
postoperative
complications,
quality
life
changes
after
pancreatectomy
patients.
This
evaluated
patients
(aged
≥
65)
scheduled
for
August
2020
December
2023.
Patients
who
underwent
Comprehensive
Geriatric
Assessment
signed
informed
consent
were
included.
Frailty
determined
by
multidimensional
frailty
score
more
than
5.
Neurohumoral
measured
using
ACTH
stimulation
test,
cardiovascular
autonomic
function
orthostatic
blood
pressure
measurement,
cognitive-motor
dual-task
gait
tests.
primary
outcome
secondary
deterioration
one
year
pancreatectomy.
A
total
57
included
analysis.
Among
them,
17
(29.8%)
classified
as
frail,
10
(17.5%)
experienced
12
(24.5%)
had
worsened
year.
Low
slow
usual
speed
associated
frailty.
Diminished
cortisol
responsiveness
correlated
complications.
Quality
differences
(serial
7)
fast
speed.
highlights
potential
multidomain
components,
clinical
outcomes
undergoing
Future
research
should
focus
on
developing
robust,
objective,
reliable
metrics
use.
Aging & Mental Health,
Год журнала:
2024,
Номер
28(11), С. 1532 - 1539
Опубликована: Июнь 24, 2024
A
significant
gap
currently
exists
in
the
availability
of
reliable
and
scientifically
rigorous
measures
for
evaluating
resilience
among
older
Arabic-speaking
populations.
The
primary
objective
this
study
was
to
assess
psychometric
properties
an
Arabic
adaptation
15-item
Resilience
Scale
Older
Adults
(RSOA)
a
sample
Egyptian
adults.
Abstract
Background
In
recent
years,
researchers
have
been
examining
the
impact
of
work-life
balance
(WLB)
on
mental
health,
considering
it
as
a
potential
risk
factor.
However,
remains
unclear
whether
traditional
understanding
WLB
applies
to
older
adults
who
worked
for
fewer
hours
before
full
retirement
and
whose
children
are
likely
be
independent
adults.
Therefore,
this
study
aims
propose
modified
form
specifically
Within
context,
we
hypothesize
that
an
optimum
between
working
social
engagement
protects
against
depressive
symptoms
among
Method
We
conducted
analysis
using
data
5,751
Korean
than
55
years
from
Longitudinal
Study
Aging
2016.
Multivariate
logistic
regression
was
used
evaluate
relationships
hours,
engagement,
symptoms.
Results
Older
35
h
per
week
were
less
experience
non-working
those
or
more
week.
Additionally,
with
high
level
informal
participation,
thus
occurring
almost
every
day
two
three
times
week,
low
such
participation
(once
month
less).
Furthermore,
frequent
engaged
in
compared
individuals
participation.
Conclusions
Maintaining
optimal
number
degree
necessary
minimize
Based
these
findings,
suggest
fulfillment
work
life
their
important
work–life
balance.
Abstract
Background
Anxiety
disorders
in
middle-aged
and
older
adults
are
an
important
public
health
concern
China.
Based
on
the
data
global
disease
burden
(GDB)
research
database,
this
study
evaluated
analyzed
trend
of
patients
living
with
anxiety
China
past
30
years.
Methods
The
incidence
disability-adjusted
life
years
(DALYs)
for
individuals
aged
45–89
were
collected
from
Global
Burden
Disease
Study
2019,
effects
age,
period,
cohort
DALY
rate
analysed
using
age-period-cohort
model.
Because
COVID-19
pandemic,
database
has
not
been
updated
since
2019.
However,
did
affect
analysis
future
trends
study,
which
combined
three
decades
1990
to
Results
(1)
overall
age-standardised
(ASIR)
(ASDR)
decreased
by
4.0
7.7%
respectively,
ASIR
ASDR
always
higher
women
than
men.
(2)Age-period-cohort
showed
that
net
drifts
−
0.27%
0.55%
per
year,
respectively.
For
both
genders,
local
lower
zero
those
45–79
80–89
years;
all
groups.
(3)
From
1990–1994
2015–2019,
relative
risks
disorder
5.6
7.3%
men
4.3
11.7%
women,
Conclusion
relieved
over
however,
recent
ASDR,
have
shown
adverse
trends.
age
while
a
increasing
first
decreasing
afterwards.
Journal of Medical Internet Research,
Год журнала:
2024,
Номер
26, С. e53450 - e53450
Опубликована: Июль 25, 2024
Resilience
is
a
protective
factor
in
healthy
aging,
helping
to
maintain
and
recover
physical
mental
functions.
The
Illness
Model
has
proven
effective
fostering
resilience
well-being.
Physical
activity
crucial
for
older
adults'
independence
well-being,
even
as
aging
causes
progressive
decline.
Additionally,
adults
face
challenges
such
spousal
loss
disability,
making
preventive
intervention
strategies
necessary.
