Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Апрель 12, 2023
Abstract
In
recent
years,
mesoporous
silica
nanoparticles
(MSNs)
have
been
applied
in
various
biomedicine
fields
like
bioimaging,
drug
delivery,
and
antibacterial
alternatives.
MSNs
could
be
manufactured
through
green
synthetic
methods
as
environmentally
friendly
sustainable
synthesis
approaches,
to
improve
physiochemical
characteristics
for
biomedical
applications.
the
present
research,
we
used
Rutin
(Ru)
extract,
a
biocompatible
flavonoid,
reducing
agent
nonsurfactant
template
of
Ag-decorated
MSNs.
Transmission
electron
microscopy
(TEM),
zeta-potential,
x-ray
powder
diffraction
(XRD),
fourier
transform
infrared
(FTIR)
spectroscopy
analysis,
scanning
(SEM),
brunauer–emmett–teller
(BET)
energy-dispersive
system
(EDS)
were
evaluate
physical
characteristics.
The
antimicrobial
properties
evaluated
against
Staphylococcus
aureus
(S
.
aureus),
Escherichia
coli
(
E
coli),
also
different
types
candida.
cytotoxicity
test
was
performed
by
using
MTT
assay.
Based
on
findings,
significant
efficacy
Ru-Ag-decorated
both
gram
positive
negative
bacteria
fungi
detected
well
acceptable
safety
low
even
at
lower
concentrations.
Our
results
given
straightforward
cost-effective
method
fabricating
biodegradable
applications
these
domains
appear
promising.
Kuwait Journal of Science,
Год журнала:
2024,
Номер
51(2), С. 100212 - 100212
Опубликована: Фев. 22, 2024
Hospitals
discharge
large
amounts
of
pathogenic
microbes
into
municipal
wastewater
and
aquatic
environments,
posing
significant
challenges
in
terms
human
health
ecological
impacts.
It
is
crucial
to
develop
implement
effective
techniques
for
managing
treating
such
wastewater.
In
this
study,
we
aimed
design
a
potential
strategy
the
treatment
microbial
hospital
(HWW)
by
utilizing
combination
cold
plasma
(CP)
silver
nanoparticles
(Ag
NPs).
Melia
azedarach
(M.
azedarach)
leaf
extract
was
used
biosynthesis
Ag
NPs
green
method.
Various
were
employed
characterization.
The
results
obtained
from
ultra-violet
visible
(UV–vis)
spectroscopy
showed
ab
absorbance
peak
at
430
nm.
scanning
electron
microscope
(SEM)
images
revealed
that
biosynthesized
appeared
spherical
with
an
average
size
13.6
X-ray
diffraction
(XRD)
analysis
determined
formation
NPs.
Fourier-transform
infrared
(FTIR)
indicated
involvement
biomolecules
reduction
stabilization
For
HWW,
antibacterial
activity
evaluated
highest
concentration
(1:1),
while
CP
tested
longest
duration
exposure
(60
s).
number
bacterial
colonies
18
5
colonies,
respectively,
compared
control
sample
(without
treatment),
which
had
175
colonies.
Moreover,
combined
resulted
complete
inhibition
growth,
zero
all
samples
conditions.
Based
on
these
findings,
believe
synergistic
effect
between
holds
promise
as
advanced
technology
elimination
HWW.
This
has
contribute
more
sustainable
environmentally
responsible
healthcare
system.
Pharmaceutics,
Год журнала:
2023,
Номер
15(4), С. 1181 - 1181
Опубликована: Апрель 7, 2023
The
development
of
antiviral
treatment
and
anticancer
theragnostic
agents
in
recent
decades
has
been
associated
with
nanotechnologies,
primarily
inorganic
nanoparticles
(INPs)
metal
oxides.
large
specific
surface
area
its
high
activity
make
it
easy
to
functionalize
INPs
various
coatings
(to
increase
their
stability
reduce
toxicity),
(allowing
retention
the
affected
organ
or
tissue),
drug
molecules
(for
antitumor
therapy).
ability
magnetic
(MNPs)
iron
oxides
ferrites
enhance
proton
relaxation
tissues
serve
as
resonance
imaging
contrast
is
one
most
promising
applications
nanomedicine.
Activation
MNPs
during
hyperthermia
by
an
external
alternating
field
a
method
for
targeted
cancer
therapy.
As
therapeutic
tools,
are
carriers
delivery
pharmaceuticals
(either
antiviral)
via
targeting
(in
case
MNPs),
passive
active
(by
attaching
affinity
ligands)
targeting.
plasmonic
properties
Au
(NPs)
application
photothermal
photodynamic
therapies
have
extensively
explored
recently
tumor
treatment.
Ag
NPs
alone
combination
medicines
reveal
new
possibilities
prospects
relation
hyperthermia,
therapies,
imaging,
framework
therapy
presented
this
review.
