Medical Oncology, Год журнала: 2025, Номер 42(7)
Опубликована: Май 31, 2025
Язык: Английский
Medical Oncology, Год журнала: 2025, Номер 42(7)
Опубликована: Май 31, 2025
Язык: Английский
Biomass Conversion and Biorefinery, Год журнала: 2025, Номер unknown
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
1International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142048 - 142048
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
1Biomacromolecules, Год журнала: 2024, Номер 26(1), С. 341 - 362
Опубликована: Дек. 25, 2024
Acyclovir (ACV) is a potentially effective antiviral medication; however, it has serious drawback, which its poor solubility, bioavailability, and short half-life. The goal of this study to improve drawbacks through the synthesis nanogels. In study, cross-linked hyaluronic acid-grafted poly(acrylamide-co-itaconic acid) nanogel synthesized successfully free radical polymerization used as safe pH-responsive carrier for ACV. nanogels showed pH response in vitro vivo. prepared C5 (1:1 ratio acrylamide: itaconic), had highest grafting efficiency, maximum swelling, drug loading, release 7.4, higher than 1.2. Also, C5, large surface area, good stability, matrices shrank acidic medium protected drug, while basic medium, expanded released ACV sustained manner improved bioavailability half-life
Язык: Английский
Процитировано
6International Journal of Biological Macromolecules, Год журнала: 2025, Номер 306, С. 141675 - 141675
Опубликована: Март 6, 2025
Язык: Английский
Процитировано
0Carbon Trends, Год журнала: 2025, Номер unknown, С. 100507 - 100507
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Biomacromolecules, Год журнала: 2025, Номер unknown
Опубликована: Май 8, 2025
Diabetic ulcers are associated with oxidative stress, inflammation, decreased synthesis of pro-healing mediators, and impaired vascularization, which convert the wound from acute to chronic delay healing. An extended duration healing raises possibility complications such as infection, sepsis, even amputation. The objective this study is a plasticized cross-linked hyaluronic acid (HA)-grafted poly(acrylamide-co-itaconic acid) nanogel nontoxic adhesive, swellable, antibacterial dressing good mechanical properties protect pathogens accelerate process, in addition decreasing stress inflammatory cytokines while increasing anti-inflammatory angiogenesis. Nanogel H3 ratio (AM/IA) (3:1) showed excellent adhesion properties, biocompatibility, swelling, antioxidant, efficiencies. It great closure vitro vivo downregulation cytokines, upregulation enhanced angiogenesis on diabetic nondiabetic wounds.
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2025, Номер 311, С. 144100 - 144100
Опубликована: Май 9, 2025
Язык: Английский
Процитировано
0Medical Oncology, Год журнала: 2025, Номер 42(7)
Опубликована: Май 31, 2025
Язык: Английский
Процитировано
0