Weight Reduction with GLP-1 Agonists and Paths for Discontinuation While Maintaining Weight Loss
Biomolecules,
Год журнала:
2025,
Номер
15(3), С. 408 - 408
Опубликована: Март 13, 2025
Worldwide,
nearly
40%
of
adults
are
overweight
and
13%
obese.
Health
consequences
excess
weight
include
cardiovascular
diseases,
type
2
diabetes,
dyslipidemia,
increased
mortality.
Treating
obesity
is
challenging
calorie
restriction
often
leads
to
rebound
gain.
Treatments
such
as
bariatric
surgery
create
hesitancy
among
patients
due
their
invasiveness.
GLP-1
medications
have
revolutionized
loss
can
reduce
body
in
obese
by
between
15%
25%
on
average
after
about
1
year.
Their
mode
action
mimic
the
endogenous
GLP-1,
an
intestinal
hormone
that
regulates
glucose
metabolism
satiety.
However,
drugs
carry
known
risks
and,
since
use
for
recent,
may
unforeseen
well.
They
a
boxed
warning
people
with
personal
or
family
history
medullary
thyroid
carcinoma
multiple
endocrine
neoplasia
syndrome
2.
Gastrointestinal
adverse
events
(nausea,
vomiting,
diarrhea)
fairly
common
while
pancreatitis
obstruction
rarer.
There
be
lean
mass
well
premature
facial
aging.
A
significant
disadvantage
using
these
high
rate
regain
when
they
discontinued.
Achieving
success
pharmacologic
treatment
then
weaning
avoid
future
negative
effects
would
ideal.
Язык: Английский
Demographic and lifestyle factors affecting BMI and weight satisfaction of physicians in Babylon Province
Qais Ismaeel Kadhem,
Ahmed Abdul Hussain Gburi Alhilly,
Nibras Alaa Hussain
и другие.
Polish Annals of Medicine,
Год журнала:
2025,
Номер
unknown, С. 1 - 6
Опубликована: Янв. 10, 2025
Introduction
Obesity,
defined
by
a
high
body
mass
index
(BMI),
is
significant
global
health
issue
that
has
increased
over
recent
decades,
leading
to
higher
rates
of
type
2
diabetes,
heart
diseases,
and
some
cancers.
Aim
To
explore
the
demographic,
socioeconomic,
lifestyle
factors
affecting
obesity
in
medical
professionals,
identify
causes,
create
effective
weight
control
strategies.
Material
methods
A
cross-sectional
study
200
physicians
utilized
face-to-face
interviews
standardized
questionnaire
gather
data
on
demographics,
lifestyle,
management,
with
BMI
assessed
according
WHO
guidelines.
Results
discussion
In
Babylon,
troubling
75.5%
are
overweight
or
obese,
highest
among
women
aged
46,
likely
due
menopause.
Additionally,
78%
those
who
do
not
exercise
regularly
have
elevated
levels.
Factors
like
job
stress
ineffective
management
exacerbate
obesity,
particularly
private
clinic
physicians.
Notably,
56.5%
physician’s
express
dissatisfaction
their
weight,
especially
categories.
Conclusions
reveals
strong
correlation
between
age
female
physicians,
soaring
59.1%
46
older,
primarily
Overall,
fall
into
obese
categories,
middle-aged
individuals.
Key
influencing
include
insufficient
failed
loss
efforts.
Furthermore,
there
notable
inverse
relationship
individuals
compared
normal
weight.
Язык: Английский
Configural path of obesity: linkage of physical activity and lifestyle based on fuzzy-set qualitative comparative analysis
Frontiers in Public Health,
Год журнала:
2025,
Номер
13
Опубликована: Март 28, 2025
Obesity
plays
a
significant
role
in
the
burden
of
various
health
conditions,
it
is
not
only
global
issue
but
challenges
national
public
system.
Some
regions
China
still
face
high
prevalence
obesity,
and
broadly
recognized
that
physical
activities
interact
with
lifestyle
different
pathways
would
affect
obesity.
We
aim
to
capture
configurational
paths
lead
using
fuzzy
set
Qualitative
Comparative
Analysis.
Eight
obesity-related
variables
were
involved,
data
collected
between
January
1,
2021,
31,
2022.
The
study
shows
six
result
which
necessary
condition
"educational
status,"
core
conditions
"the
time
exercise"
"weekly
sitting
time*sleeping
less
than
6
h*second
hand
smoking
exposure
on
average
4-6
days
per
week
*keep
excising
4
times
week*
exercise
intensity
shortness
breath,
markedly
increased
heart
rate,
heavy
sweating"
play
an
important
obesity
outcome,
solution
exhibits
acceptable
consistency
0.50.
0.76,
coverage
0.31.
Besides
factors
play(s)
development
we
have
consider
multiple
activity
cross-cutting
effect
This
can
offer
better
understanding
mechanisms
cause
by
identifying
characterizing
regional
population,
help
develop
effective
protective
measure
for
Язык: Английский
Weight loss methods and risk of depression: Evidence from the NHANES 2005-2018 cohort
Journal of Affective Disorders,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
Язык: Английский
Gewichtneutrale Ansätze zur Behandlung von Adipositas
UlrikeA. Gisch,
Teresa Bilic
Aktuelle Ernährungsmedizin,
Год журнала:
2025,
Номер
50(02), С. 115 - 128
Опубликована: Апрель 1, 2025
In
Deutschland
sind
19%
der
Erwachsenen
von
Adipositas
betroffen
1.
Traditionelle
Gewichtsreduktionsprogramme
zur
Behandlung
bringen
häufig
nicht
die
gewünschten
Erfolge
bei
Gewichtsreduktion.
Es
werden
daher
dringend
alternative
Behandlungsansätze
benötigt,
um
Versorgung
Personen
mit
zu
verbessern.
Bisherige
Interventionen
gewichtsneutralen
Ansätzen
zeigen
vielversprechende
Ergebnisse.
Effects of antidepressants on body weight in patients treated in a naturalistic setting in Oman
Middle East Current Psychiatry,
Год журнала:
2025,
Номер
32(1)
Опубликована: Янв. 14, 2025
Abstract
Background
The
rising
use
of
antidepressants
is
critical
for
managing
mental
health
disorders,
but
weight
gain
a
concerning
side
effect,
particularly
with
certain
classes
like
TCAs
and
SSRIs.
This
study
aims
to
investigate
changes
in
Omani
patients
prescribed
paroxetine,
fluoxetine,
mirtazapine,
or
venlafaxine.
Method
A
cross-sectional
conducted
from
January
June
2023
at
Sultan
Qaboos
University
Hospital
recruited
adults
disorders
on
these
medications.
Weight
measurements
were
taken
baseline
follow-up,
clinically
significant
defined
as
≥
7%
increase.
Results
total
135
participants
analyzed,
showing
mean
5.54
kg,
60.7%
experiencing
gain.
Mirtazapine
paroxetine
exhibited
the
highest
average
increases
(7.51
kg
8.05
respectively)
compared
fluoxetine
(0.69
kg)
venlafaxine
(4.32
kg).
No
demographic
factors
influenced
(
p
=
0.213).
Conclusion
highlights
among
antidepressants,
mirtazapine
paroxetine.
underscores
importance
monitoring
clinical
practice
necessitates
further
investigations
into
individualized
treatment
strategies
manage
both
weight-related
concerns.
Язык: Английский
Economic Rationality and Health Behavior: Investigating the Link Between Financial Literacy and the BMI
Kenji Ogura,
Honoka Nabeshima,
Tomoka Kiba
и другие.
Behavioral Sciences,
Год журнала:
2025,
Номер
15(5), С. 632 - 632
Опубликована: Май 6, 2025
Obesity
is
a
major
global
health
concern
related
to
chronic
diseases
and
rising
healthcare
costs.
While
previous
studies
focused
on
diet
habits,
environmental
issues,
physical
activity,
financial
literacy
remains
an
overlooked
factor
in
weight
management.
This
study
examined
the
relationship
between
body
mass
index
(BMI),
using
as
proxy
for
rational
decision-making.
A
quantitative
approach
was
employed,
where
linear
regression
analyzed
BMI
continuous
variable
probit
assessed
overweight,
normal
weight,
underweight
categories.
nationwide
survey,
Preference
Parameter
Study,
conducted
by
Osaka
University,
Japan,
United
States,
provided
data
this
study.
The
results
indicate
significant
negative
association
BMI,
with
higher
linked
lower
greater
likelihood
of
maintaining
weight.
key
control
variables,
including
impatience,
gender,
education,
income,
smoking,
also
significantly
affected
BMI.
These
findings
reflect
strong
correlation
status;
however,
due
limitations,
causal
inferences
could
not
be
made.
We
acknowledge
potential
endogeneity
cross-sectional
nature
limitations.
Thus,
while
our
suggest
role
promoting
behavior,
policy
implications
should
interpreted
caution.
Future
research
explore
targeted
interventions
across
various
demographic
groups
maximize
impact.
Язык: Английский