A review on plant extract mediated green synthesis of zinc oxide nanoparticles and their biomedical applications

Results in Chemistry, Год журнала: 2024, Номер 7, С. 101368 - 101368

Опубликована: Янв. 1, 2024

Zinc oxide nanoparticles (ZnO NPs) exhibit distinctive characteristics, making them highly sought-after in many sectors. Nevertheless, conventional techniques for producing ZnO-NPs are linked to environmental and health hazards due toxic substances. In this review, we study zinc synthesized from plant extracts their subsequent biomedical uses detail. Research shows that several different employed manufacturing ZnO nanoparticles. Leaves, fruits, seeds, roots, complete plants all included these extracts. Phytochemicals such as phenolic compounds, alkaloids, flavonoids, terpenoids a part of biological matrices. compounds show bioreduction mechanism, act stabilizing reducing agent. The attributes (NPs), including size, shape, crystallinity, may be altered by adjusting the extract variety, concentration, synthesis conditions. Consequently, formed display notable diversity physical chemical subsequently impacting functionality. manufactured using green methods extensive, beneficial effects antibacterial activity against various pathogens, anti-inflammatory possible anticancer activities. Nanoparticles have been integrated into wound dressings, used carriers medication delivery, utilized biosensing imaging applications. enhanced biocompatibility reduced toxicity green-processed techniques, comparison those made approaches, make very appealing use contexts. Moreover, paper examines mechanisms, explicitly focusing on involvement phytochemicals processes reduction stabilization. Additionally, emphasizes difficulties potential future directions optimizing processes, increasing capacity, facilitating therapeutic

Язык: Английский

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ZnO nanostructures – Future frontiers in photocatalysis, solar cells, sensing, supercapacitor, fingerprint technologies, toxicity, and clinical diagnostics

Coordination Chemistry Reviews, Год журнала: 2024, Номер 515, С. 215942 - 215942

Опубликована: Май 20, 2024

Язык: Английский

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New frontiers of invasive plants for biosynthesis of nanoparticles towards biomedical applications: A review

The Science of The Total Environment, Год журнала: 2022, Номер 857, С. 159278 - 159278

Опубликована: Окт. 7, 2022

Язык: Английский

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Zinc oxide loaded chitosan-elastin-sodium alginate nanocomposite gel using freeze gelation for enhanced adipose stem cell proliferation and antibacterial properties

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 233, С. 123519 - 123519

Опубликована: Фев. 8, 2023

Язык: Английский

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Alchemy in Nature: The Role of Lawsonia inermis Extract Choice in Crafting Potent Anticancer Metal Nanoparticles

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Янв. 11, 2025

Phyto-nanotechnology provides an eco-friendly approach for synthesizing biocompatible metal nanoparticles (NPs) with therapeutic potential.

Язык: Английский

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Bio-Assisted Synthesis and Characterization of Zinc Oxide Nanoparticles from Lepidium sativum and Their Potent Antioxidant, Antibacterial and Anticancer Activities

Biomolecules, Год журнала: 2022, Номер 12(6), С. 855 - 855

Опубликована: Июнь 20, 2022

Nanotechnology is an emerging area of research that deals with the production, manipulation, and application nanoscale materials. Bio-assisted synthesis particular interest nowadays, to overcome limitations associated physical chemical means. The aim this study was synthesize ZnO nanoparticles (NPs) for first time, utilizing seed extract Lepidium sativum. synthesized NPs were confirmed through various spectroscopy imagining techniques, such as XRD, FTIR, HPLC, SEM. characterized then examined in vitro biological assays. Crystalline, hexagonal-structured average particle size 25.6 nm obtained. Biosynthesized exhibited potent antioxidant activities, effective α-amylase inhibition, moderate urease inhibition (56%), high lipase-inhibition (71%) cytotoxic potential, significant antibacterial activity. Gene expression caspase HepG2 cells enhanced along elevated production ROS/RNS, while membrane integrity disturbed upon exposure NPs. Overall results indicated bio-assisted exhibit excellent potential could be exploited future biomedical applications. particularly antimicrobial cancer therapeutics. Moreover, comprehensive on sativum-mediated evaluation their activities.

Язык: Английский

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Ag-doped ZnO nanoparticles synthesized through green method using Artemisia turcomanica extract induce cytotoxicity and apoptotic activities against AGS cancer cells: an in vitro study

Journal of nanostructure in chemistry, Год журнала: 2023, Номер 14(6), С. 403 - 418

Опубликована: Апрель 19, 2023

Язык: Английский

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Eco-friendly zinc oxide nanoparticle biosynthesis powered by probiotic bacteria

Applied Microbiology and Biotechnology, Год журнала: 2025, Номер 109(1)

Опубликована: Янв. 29, 2025

Abstract The rapid advancement of nanotechnology, particularly in the realm pharmaceutical sciences, has significantly transformed potential for treating life-threatening diseases. A pivotal aspect this evolution is emergence “green nanotechnology,” which emphasizes environmentally sustainable synthesis raw materials through biological processes. This review focuses on and application zinc oxide (ZnO) nanoparticles (NPs) from probiotic bacteria, those sourced wastewater. Microorganisms wastewater tolerate harmful elements enzymatically convert toxic heavy metals into eco-friendly materials. These bacteria are instrumental ZnO NPs exhibit remarkable antimicrobial properties with diverse industrial applications. As challenge drug-resistant pathogens escalates, innovative strategies combating microbial infections essential. explores intersection microbiology, antibacterial resistance, highlighting importance selecting suitable synthesizing potent activity. Additionally, addresses biofunctionalization their applications environmental remediation therapeutic innovations, including wound healing, antibacterial, anticancer treatments. Eco-friendly NP relies identification these “nano-factories.” Targeting can uncover new capabilities, advancing friendly production methods. Key points • Innovative needed to combat like MRSA. Wastewater-derived an method synthesis. show significant activity against various pathogens.

Язык: Английский

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Latent Potential of Multifunctional Selenium Nanoparticles in Neurological Diseases and Altered Gut Microbiota

Materials, Год журнала: 2023, Номер 16(2), С. 699 - 699

Опубликована: Янв. 11, 2023

Neurological diseases remain a major concern due to the high world mortality rate and absence of appropriate therapies cross blood–brain barrier (BBB). Therefore, focus is on development such strategies that not only enhance efficacy drugs but also increase their permeability in BBB. Currently, nano-scale materials seem be an approach treating neurological based drug-loading capacity, reduced toxicity, targeted delivery, enhanced therapeutic effect. Selenium (Se) essential micronutrient has been remarkable interest owing its role physiological activity nervous system, i.e., signal transmission, memory, coordination, locomotor activity. A deficiency Se leads various as Parkinson’s disease, epilepsy, Alzheimer’s disease. neuroprotective (selenium) nanoparticles (SeNPs) are particular treat diseases. To date, many studies investigate altered microbiota with diseases; thus, current review focused recent advancement field nanotechnology, considering SeNPs cure diseases, investigating potential microbiota.

Язык: Английский

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Sustainable synthesis of bionanomaterials using non-native plant extracts for maintaining ecological balance: A computational bibliography analysis

Journal of Environmental Management, Год журнала: 2024, Номер 358, С. 120892 - 120892

Опубликована: Апрель 25, 2024

Biological approaches via biomolecular extracts of bacteria, fungi, or plants have recently been introduced as an alternative approach to synthesizing less nontoxic nanomaterials, compared conventional physical and chemical approaches. Among these biological methods, plant-mediated (phytosynthesis) are reported be highly beneficial for large-scale, nanomaterial synthesis. However, synthesis nanomaterials using native plant extract can lead bioprospecting issues deforestation challenges. On the other hand, non-native invasive non-indigenous a particular geographic location that grow spread rapidly, ultimately disrupting local endogenous communities ecosystems. Thus, controlling eradicating before they damage ecosystem is necessary. Even though mechanical, chemical, available control plants, all methods possess certain limitations, such environmental toxicity, disturbance in nutrient cycle, loss genetic integrity. Therefore, were proposed novel sustainable source phytochemicals preparing green chemistry, mainly metallic nanoparticles, native, agriculture-based, medicinal plants. This work aims cover literature gap on bionanomaterial with overview bibliography analysis data mining advanced visualization tools. In addition, potential sustainable, chemistry-based preparation maintaining ecological balance, mechanism formation phytochemicals, their possible applications promote also discussed. The revealed only average 4 articles published last 10 years (2013-2023) non-native/invasive synthesis, which shows significance this article.

Язык: Английский

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