International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(21), P. 11621 - 11621
Published: Oct. 29, 2024
This
work
presents
a
green
synthesis
route,
which
utilises
extracts
from
an
indigenous
plant
in
South
Africa,
eastern
and
southern
Africa
that
is
understudied
underutilised,
for
preparing
zinc
oxide
nanoparticles
(ZnO
NPs).
study
involved
optimisation
of
the
method
using
Leonotis
ocymifolia
(L.O.)
performing
comparative
studies
on
effects
different
(Zn)
salt
precursors;
sulphate
heptahydrate
(Z001)
acetate
dihydrate
(Z002)
to
synthesise
ZnO
NPs.
The
also
compared
L.O-mediated
NPs
chemical-mediated
(Z003).
as-prepared
were
tested
their
effectiveness
photodegradation
methylene
blue
(MB)
dye.
Furthermore,
antibacterial
conducted
agar
well
diffusion
Escherichia
coli
(E.
coli)
Staphylococcus
aureus
(S.
aureus)
bacteria.
structural,
morphological,
optical
characteristics
synthesised
analysed
XRD,
FTIR,
SEM,
EDS,
DRS,
BET
techniques.
XRD
results
indicated
had
smaller
crystallite
sizes
(18.24–19.32
nm)
than
chemically
counterparts
(21.50
nm).
FTIR
confirmed
presence
biomolecules
surface
NPs,
DRS
analysis
revealed
bandgap
energies
between
3.07
3.18
eV.
EDS
chemical
composition
made
up
Zn
O
atoms.
Photocatalytic
demonstrated
exhibited
superior
degradation
efficiency
MB
dye
(89.81%)
(56.13%)
under
ultraviolet
(UV)
light
240
min.
Antibacterial
tests
showed
more
effective
against
S.
E.
coli.
enhanced
photocatalytic
properties
highlight
potential
environmental
remediation
antimicrobial
applications,
thus
supporting
sustainable
development
goals.
Results in Chemistry,
Journal Year:
2024,
Volume and Issue:
7, P. 101368 - 101368
Published: Jan. 1, 2024
Zinc
oxide
nanoparticles
(ZnO
NPs)
exhibit
distinctive
characteristics,
making
them
highly
sought-after
in
many
sectors.
Nevertheless,
conventional
techniques
for
producing
ZnO-NPs
are
linked
to
environmental
and
health
hazards
due
toxic
substances.
In
this
review,
we
study
zinc
synthesized
from
plant
extracts
their
subsequent
biomedical
uses
detail.
Research
shows
that
several
different
employed
manufacturing
ZnO
nanoparticles.
Leaves,
fruits,
seeds,
roots,
complete
plants
all
included
these
extracts.
Phytochemicals
such
as
phenolic
compounds,
alkaloids,
flavonoids,
terpenoids
a
part
of
biological
matrices.
compounds
show
bioreduction
mechanism,
act
stabilizing
reducing
agent.
The
attributes
(NPs),
including
size,
shape,
crystallinity,
may
be
altered
by
adjusting
the
extract
variety,
concentration,
synthesis
conditions.
Consequently,
formed
display
notable
diversity
physical
chemical
subsequently
impacting
functionality.
manufactured
using
green
methods
extensive,
beneficial
effects
antibacterial
activity
against
various
pathogens,
anti-inflammatory
possible
anticancer
activities.
Nanoparticles
have
been
integrated
into
wound
dressings,
used
carriers
medication
delivery,
utilized
biosensing
imaging
applications.
enhanced
biocompatibility
reduced
toxicity
green-processed
techniques,
comparison
those
made
approaches,
make
very
appealing
use
contexts.
Moreover,
paper
examines
mechanisms,
explicitly
focusing
on
involvement
phytochemicals
processes
reduction
stabilization.
Additionally,
emphasizes
difficulties
potential
future
directions
optimizing
processes,
increasing
capacity,
facilitating
therapeutic
Applied Microbiology and Biotechnology,
Journal Year:
2025,
Volume and Issue:
109(1)
Published: Jan. 29, 2025
Abstract
The
rapid
advancement
of
nanotechnology,
particularly
in
the
realm
pharmaceutical
sciences,
has
significantly
transformed
potential
for
treating
life-threatening
diseases.
A
pivotal
aspect
this
evolution
is
emergence
“green
nanotechnology,”
which
emphasizes
environmentally
sustainable
synthesis
raw
materials
through
biological
processes.
This
review
focuses
on
and
application
zinc
oxide
(ZnO)
nanoparticles
(NPs)
from
probiotic
bacteria,
those
sourced
wastewater.
Microorganisms
wastewater
tolerate
harmful
elements
enzymatically
convert
toxic
heavy
metals
into
eco-friendly
materials.
These
bacteria
are
instrumental
ZnO
NPs
exhibit
remarkable
antimicrobial
properties
with
diverse
industrial
applications.
As
challenge
drug-resistant
pathogens
escalates,
innovative
strategies
combating
microbial
infections
essential.
explores
intersection
microbiology,
antibacterial
resistance,
highlighting
importance
selecting
suitable
synthesizing
potent
activity.
Additionally,
addresses
biofunctionalization
their
applications
environmental
remediation
therapeutic
innovations,
including
wound
healing,
antibacterial,
anticancer
treatments.
Eco-friendly
NP
relies
identification
these
“nano-factories.”
Targeting
can
uncover
new
capabilities,
advancing
friendly
production
methods.
Key
points
•
Innovative
needed
to
combat
like
MRSA.
Wastewater-derived
an
method
synthesis.
show
significant
activity
against
various
pathogens.
Biomolecules,
Journal Year:
2022,
Volume and Issue:
12(6), P. 855 - 855
Published: June 20, 2022
Nanotechnology
is
an
emerging
area
of
research
that
deals
with
the
production,
manipulation,
and
application
nanoscale
materials.
Bio-assisted
synthesis
particular
interest
nowadays,
to
overcome
limitations
associated
physical
chemical
means.
The
aim
this
study
was
synthesize
ZnO
nanoparticles
(NPs)
for
first
time,
utilizing
seed
extract
Lepidium
sativum.
synthesized
NPs
were
confirmed
through
various
spectroscopy
imagining
techniques,
such
as
XRD,
FTIR,
HPLC,
SEM.
characterized
then
examined
in
vitro
biological
assays.
Crystalline,
hexagonal-structured
average
particle
size
25.6
nm
obtained.
Biosynthesized
exhibited
potent
antioxidant
activities,
effective
α-amylase
inhibition,
moderate
urease
inhibition
(56%),
high
lipase-inhibition
(71%)
cytotoxic
potential,
significant
antibacterial
activity.
Gene
expression
caspase
HepG2
cells
enhanced
along
elevated
production
ROS/RNS,
while
membrane
integrity
disturbed
upon
exposure
NPs.
Overall
results
indicated
bio-assisted
exhibit
excellent
potential
could
be
exploited
future
biomedical
applications.
particularly
antimicrobial
cancer
therapeutics.
Moreover,
comprehensive
on
sativum-mediated
evaluation
their
activities.
Materials,
Journal Year:
2023,
Volume and Issue:
16(2), P. 699 - 699
Published: Jan. 11, 2023
Neurological
diseases
remain
a
major
concern
due
to
the
high
world
mortality
rate
and
absence
of
appropriate
therapies
cross
blood–brain
barrier
(BBB).
Therefore,
focus
is
on
development
such
strategies
that
not
only
enhance
efficacy
drugs
but
also
increase
their
permeability
in
BBB.
Currently,
nano-scale
materials
seem
be
an
approach
treating
neurological
based
drug-loading
capacity,
reduced
toxicity,
targeted
delivery,
enhanced
therapeutic
effect.
Selenium
(Se)
essential
micronutrient
has
been
remarkable
interest
owing
its
role
physiological
activity
nervous
system,
i.e.,
signal
transmission,
memory,
coordination,
locomotor
activity.
A
deficiency
Se
leads
various
as
Parkinson’s
disease,
epilepsy,
Alzheimer’s
disease.
neuroprotective
(selenium)
nanoparticles
(SeNPs)
are
particular
treat
diseases.
To
date,
many
studies
investigate
altered
microbiota
with
diseases;
thus,
current
review
focused
recent
advancement
field
nanotechnology,
considering
SeNPs
cure
diseases,
investigating
potential
microbiota.
Journal of Environmental Management,
Journal Year:
2024,
Volume and Issue:
358, P. 120892 - 120892
Published: April 25, 2024
Biological
approaches
via
biomolecular
extracts
of
bacteria,
fungi,
or
plants
have
recently
been
introduced
as
an
alternative
approach
to
synthesizing
less
nontoxic
nanomaterials,
compared
conventional
physical
and
chemical
approaches.
Among
these
biological
methods,
plant-mediated
(phytosynthesis)
are
reported
be
highly
beneficial
for
large-scale,
nanomaterial
synthesis.
However,
synthesis
nanomaterials
using
native
plant
extract
can
lead
bioprospecting
issues
deforestation
challenges.
On
the
other
hand,
non-native
invasive
non-indigenous
a
particular
geographic
location
that
grow
spread
rapidly,
ultimately
disrupting
local
endogenous
communities
ecosystems.
Thus,
controlling
eradicating
before
they
damage
ecosystem
is
necessary.
Even
though
mechanical,
chemical,
available
control
plants,
all
methods
possess
certain
limitations,
such
environmental
toxicity,
disturbance
in
nutrient
cycle,
loss
genetic
integrity.
Therefore,
were
proposed
novel
sustainable
source
phytochemicals
preparing
green
chemistry,
mainly
metallic
nanoparticles,
native,
agriculture-based,
medicinal
plants.
This
work
aims
cover
literature
gap
on
bionanomaterial
with
overview
bibliography
analysis
data
mining
advanced
visualization
tools.
In
addition,
potential
sustainable,
chemistry-based
preparation
maintaining
ecological
balance,
mechanism
formation
phytochemicals,
their
possible
applications
promote
also
discussed.
The
revealed
only
average
4
articles
published
last
10
years
(2013-2023)
non-native/invasive
synthesis,
which
shows
significance
this
article.
