SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2 DOI Creative Commons
Elena Zavyalova,

Oganes Ambartsumyan,

Gleb Zhdanov

и другие.

Nanomaterials, Год журнала: 2021, Номер 11(6), С. 1394 - 1394

Опубликована: Май 25, 2021

During the COVID-19 pandemic, development of sensitive and rapid techniques for detection viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool new due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity biosensors. Existing SERS-based aptasensors virus are either inapplicable quantitative determination or sophisticated expensive construction implementation. In this paper, we a SERS-aptasensor based on colloidal solutions which combines rapidity in SARS-CoV-2 virus, discriminating it from other respiratory viruses.

Язык: Английский

Non‐Invasive Thermal Therapy for Tissue Engineering and Regenerative Medicine DOI
Longfei Li, Xiaodi Zhang, Jun Zhou

и другие.

Small, Год журнала: 2022, Номер 18(36)

Опубликована: Апрель 27, 2022

Abstract Owing to the development of nanotechnology and noninvasive treatment, thermal therapy in combination with external stimuli has been applied for tissue engineering regenerative medicine (TERM), which attracted more attention recent years. In this review, progress applying a variety non‐invasive therapeutic modalities TERM, including photothermal therapy, magnetic thermotherapy, ultrasound as well other therapeutics are discussed. The parameters conditions that need be considered regulated realize well‐controlled regeneration also Afterwards, current concerns challenges putting into clinical applications pointed out. At last, perspectives provided future directions, aiming providing opportunities novel pathway TERM.

Язык: Английский

Процитировано

81

Recent advances in carbon quantum dots for virus detection, as well as inhibition and treatment of viral infection DOI Creative Commons
Yuxiang Xue, Chenchen Liu,

Gavin Andrews

и другие.

Nano Convergence, Год журнала: 2022, Номер 9(1)

Опубликована: Апрель 2, 2022

In the last decade, carbon quantum dots (CQDs), as a novel class of carbon-based nanomaterials, have received increasing attention due to their distinct properties. CQDs are ultimately small nanoparticles with an average size below 10 nm, possessing high water solubility, alluring photoluminescence, photostability, excellent biocompatibility, low/none toxicity, environmental friendliness, and sustainability, etc. history, there intermittent threats from viruses humans, animals plants worldwide, resulting in enormous crises impacts on our life, environment, economy society. Some recent studies unveiled that certain types exhibited potent antiviral activities against various such human coronavirus, arterivirus, norovirus herpesvirus. Moreover, they been successfully explored developed for different virus detections including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This article exclusively overviews discusses progress designing, synthesizing, modifying/functionalizing developing towards effective detection well inhibition treatment viral infection. Their mechanisms applications pathogenic addressed. The latest outcomes combating disease 2019 (COVID-19) utilizing also highlighted. It can be envisaged could further benefit development detectors agents added broad-spectrum activity cost-effective production.

Язык: Английский

Процитировано

77

State-of-the-art cancer biomarker detection by portable (Bio) sensing technology: A critical review DOI
Hessamaddin Sohrabi, Nadia Bolandi,

Afsaneh Hemmati

и другие.

Microchemical Journal, Год журнала: 2022, Номер 177, С. 107248 - 107248

Опубликована: Фев. 9, 2022

Язык: Английский

Процитировано

74

Green synthesis of hybrid nanoparticles for biomedical applications: A review DOI Creative Commons
Arifur Rahman, Mohammad Asaduzzaman Chowdhury, Nayem Hossain

и другие.

Applied Surface Science Advances, Год журнала: 2022, Номер 11, С. 100296 - 100296

Опубликована: Авг. 30, 2022

In recent years, the green synthesis of hybrid nanoparticles has become a cutting-edge and fascinating field research. As compared to NPs made using traditional techniques, numerous studies show significant benefits combination synthesized via greener pathway utilizing natural resources such as plants, including removal toxic pollutants, reduction following complicated chemical synthesis, environmentally friendly nature, cost-effective, convenient, dependable, affordability, stability easy way synthesize. Because these established benefits, great effort is being apply processes. We enter newly developed advanced organic/inorganic nanomaterials data table in this research look for extracts type, preparation time, temperature, morphology, size, color, medical applications. The composition, color smart were characterized by scanning electron microscopy (SEM) transmission (TEM). Furthermore, antimicrobial, anticancer, cytotoxicity effects on various bacteria, cancer cells, normal human cells are discussed. Excellent performances reported different literature. Green multimodal imaging have potential application biomedical replace techniques materials. Functional be utilized disciplines biomaterials with ultimate objective effectively detecting treating variety diseases higher success rate.

Язык: Английский

Процитировано

73

Applications of metal organic frameworks in point of care testing DOI Creative Commons
Fotouh R. Mansour, Sherin F. Hammad, Inas A. Abdallah

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 172, С. 117596 - 117596

Опубликована: Фев. 8, 2024

Diagnostic devices used in the point-of-care (POC) today play a critical role as tools to provide essential medical surveillance data and ensure that patients receive appropriate timely care. These also allow self-analysis by patient, increasing therapeutic adherence well reducing pressure on clinical structures. The development of new diagnostic tools, therefore, represents significant challenge from technological point view, both terms overcoming current weaknesses costs, accuracy, performance, an analytical view order develop are operator-independent possible. Recent breakthroughs technologies (such cell phone-dependent technologies, paper-based procedures, lab-on-a-chip devices) paving way for next generation testing (POCT). Innovative assay devices, efficient reagent storage techniques, required POCT technologies. Nanomaterials different forms, sizes, compositions, such carbon nanomaterials, quantum dots, gold silver nanoparticles, mesoporous silica metal-organic frameworks (MOFs), have been created characterized recent years. Due their specific physicochemical properties, MOF nanoparticles increasingly being improve performance simplify techniques. MOFs colorimetric or electrochemical carriers plasmonic biosensors be resistant environmental conditions. This review will discuss detailed 2016 2023, addition chemical synthesis characterization methods related uses applications MOF.

Язык: Английский

Процитировано

40

Phenylboronic Acid-Modified Membrane-Like Magnetic Quantum Dots Enable the Ultrasensitive and Broad-Spectrum Detection of Viruses by Lateral Flow Immunoassay DOI
Chongwen Wang,

Qing Yu,

Shuai Zheng

и другие.

ACS Nano, Год журнала: 2024, Номер 18(26), С. 16752 - 16765

Опубликована: Июнь 20, 2024

Although lateral flow immunochromatographic assay (LFIA) is an effective point-of-care testing technology, it still cannot achieve broad-spectrum and ultrasensitive detection of viruses. Herein, we propose a multiplex LFIA platform using two-dimensional graphene oxide (GO)-based magnetic fluorescent nanofilm (GF@DQD) as multifunctional probe 4-aminophenylboronic acid (APBA) recognition molecule for viral glycoprotein detection. GF@DQD-APBA with enhanced magnetic/fluorescence properties universal capture ability multiple viruses was easily prepared through the electrostatic adsorption one layer density-controlled Fe3O4 nanoparticles (NPs) thousands small CdSe/ZnS-MPA quantum dots (QDs) on monolayer GO sheet followed by chemical coupling APBA QD surface. The enabled specific determination different target test strip arbitrary combination antibody-modified strip, thus greatly improving efficiency reducing cost difficulty proposed technique can simultaneously sensitively diagnose three newly emerged within 20 min limits down to pg/mL level. excellent practicability GF@DQD-APBA-LFIA also demonstrated in 34 clinical specimens positive SARS-CoV-2, revealing its potential epidemic control on-site

Язык: Английский

Процитировано

32

Electrochemical immuno-biosensors for the detection of the tumor marker alpha-fetoprotein: A review DOI
Chenwei Shan, Zhencheng Chen, Guo‐Cheng Han

и другие.

Talanta, Год журнала: 2024, Номер 271, С. 125638 - 125638

Опубликована: Янв. 21, 2024

Язык: Английский

Процитировано

31

Mycotoxins detection in food samples through lateral flow assays (LFAs)–An update for status and prospect DOI Creative Commons

Poorya Sadeghi,

Hessamaddin Sohrabi, Mir Reza Majidi

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 176, С. 117722 - 117722

Опубликована: Апрель 30, 2024

Mycotoxins are responsible for several diseases in human and animals which impose huge medical economical burdens worldwide, especially low-income countries. Therefore, many countries set regulations maximum permissible amounts of mycotoxins food that need detection methods to monitor the mycotoxin concentration. Conventional like Enzyme‐linked immunosorbent assay (ELISA), high-performance liquid chromatography (HPLC) with fluorescence (HPLC-FLD), chromatography-tandem mass spectrometry (LC-MS/MS) gas (GC) widely used quantitatively mycotoxins. However, these have limitations make them suitable laboratories factories, but cannot be regularly daily markets. Thus, pursuit sensitive, specific, handheld, low-cost as effective elective strategies point-of-care testing (POCT) has gotten much consideration recent years. POCT is one ultimate objectives determination, so test must quick, particular, delicate, open, simple used. In this review, after a brief introduction their importance, common tools advantages disadvantages discussed, then lateral flow (LFA) systems working principles, classifications, method explained. Furthermore, some studies regarding development LFA detecting types innovations LFAs' design techniques overcoming traditional comprehensively reviewed. Various utilized extend sensitivity give quantitative sensing. Utilizing numerous visualization strategies, utilizing distinctive labeled reporters, coordination other take advantage both gadgets, utilize restrictive membranes upgrade reagent reactivity, few examined literature update use determination mycotoxins, covers. The period time from 2015 till 2023 based on data bases.

Язык: Английский

Процитировано

21

Recent advances in the highly sensitive determination of zearalenone residues in water and environmental resources with electrochemical biosensors DOI
Hessamaddin Sohrabi, Mir Reza Majidi, Omid Arbabzadeh

и другие.

Environmental Research, Год журнала: 2021, Номер 204, С. 112082 - 112082

Опубликована: Сен. 21, 2021

Язык: Английский

Процитировано

101

Aptamer-based lateral flow assay on-site biosensors DOI
Lei Huang,

Shulin Tian,

Wenhao Zhao

и другие.

Biosensors and Bioelectronics, Год журнала: 2021, Номер 186, С. 113279 - 113279

Опубликована: Апрель 24, 2021

Язык: Английский

Процитировано

92