Small,
Journal Year:
2022,
Volume and Issue:
18(36)
Published: April 27, 2022
Abstract
Owing
to
the
development
of
nanotechnology
and
noninvasive
treatment,
thermal
therapy
in
combination
with
external
stimuli
has
been
applied
for
tissue
engineering
regenerative
medicine
(TERM),
which
attracted
more
attention
recent
years.
In
this
review,
progress
applying
a
variety
non‐invasive
therapeutic
modalities
TERM,
including
photothermal
therapy,
magnetic
thermotherapy,
ultrasound
as
well
other
therapeutics
are
discussed.
The
parameters
conditions
that
need
be
considered
regulated
realize
well‐controlled
regeneration
also
Afterwards,
current
concerns
challenges
putting
into
clinical
applications
pointed
out.
At
last,
perspectives
provided
future
directions,
aiming
providing
opportunities
novel
pathway
TERM.
Nano Convergence,
Journal Year:
2022,
Volume and Issue:
9(1)
Published: April 2, 2022
In
the
last
decade,
carbon
quantum
dots
(CQDs),
as
a
novel
class
of
carbon-based
nanomaterials,
have
received
increasing
attention
due
to
their
distinct
properties.
CQDs
are
ultimately
small
nanoparticles
with
an
average
size
below
10
nm,
possessing
high
water
solubility,
alluring
photoluminescence,
photostability,
excellent
biocompatibility,
low/none
toxicity,
environmental
friendliness,
and
sustainability,
etc.
history,
there
intermittent
threats
from
viruses
humans,
animals
plants
worldwide,
resulting
in
enormous
crises
impacts
on
our
life,
environment,
economy
society.
Some
recent
studies
unveiled
that
certain
types
exhibited
potent
antiviral
activities
against
various
such
human
coronavirus,
arterivirus,
norovirus
herpesvirus.
Moreover,
they
been
successfully
explored
developed
for
different
virus
detections
including
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2).
This
article
exclusively
overviews
discusses
progress
designing,
synthesizing,
modifying/functionalizing
developing
towards
effective
detection
well
inhibition
treatment
viral
infection.
Their
mechanisms
applications
pathogenic
addressed.
The
latest
outcomes
combating
disease
2019
(COVID-19)
utilizing
also
highlighted.
It
can
be
envisaged
could
further
benefit
development
detectors
agents
added
broad-spectrum
activity
cost-effective
production.
Nano-Micro Letters,
Journal Year:
2022,
Volume and Issue:
14(1)
Published: Aug. 4, 2022
Coronavirus
disease
2019
(COVID-19)
is
a
highly
contagious
caused
by
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2).
The
gold
standard
method
for
the
diagnosis
of
SARS-CoV-2
depends
on
quantitative
reverse
transcription-polymerase
chain
reaction
till
now,
which
time-consuming
and
requires
expensive
instrumentation,
confirmation
variants
relies
further
sequencing
techniques.
Herein,
we
first
proposed
robust
technique-methodology
electrochemical
CRISPR
sensing
with
advantages
rapid,
sensitivity
specificity
detection
variant.
To
enhance
capability,
electrodes
are
uniformly
decorated
electro-deposited
nanoparticles.
Using
DNA
template
identical
to
Delta
spike
gene
sequence
as
model,
our
biosensor
exhibits
excellent
analytical
limit
(50
fM)
high
linearity
(R2
=
0.987)
over
six
orders
magnitude
dynamic
range
from
100
fM
10
nM
without
any
nucleic-acid-amplification
assays.
can
be
completed
within
1
h
stability
benefits
CRISPR-Cas
system.
Furthermore,
based
wireless
micro-electrochemical
platform,
reveals
promising
application
ability
in
point-of-care
testing.
Applied Surface Science Advances,
Journal Year:
2022,
Volume and Issue:
11, P. 100296 - 100296
Published: Aug. 30, 2022
In
recent
years,
the
green
synthesis
of
hybrid
nanoparticles
has
become
a
cutting-edge
and
fascinating
field
research.
As
compared
to
NPs
made
using
traditional
techniques,
numerous
studies
show
significant
benefits
combination
synthesized
via
greener
pathway
utilizing
natural
resources
such
as
plants,
including
removal
toxic
pollutants,
reduction
following
complicated
chemical
synthesis,
environmentally
friendly
nature,
cost-effective,
convenient,
dependable,
affordability,
stability
easy
way
synthesize.
Because
these
established
benefits,
great
effort
is
being
apply
processes.
We
enter
newly
developed
advanced
organic/inorganic
nanomaterials
data
table
in
this
research
look
for
extracts
type,
preparation
time,
temperature,
morphology,
size,
color,
medical
applications.
The
composition,
color
smart
were
characterized
by
scanning
electron
microscopy
(SEM)
transmission
(TEM).
Furthermore,
antimicrobial,
anticancer,
cytotoxicity
effects
on
various
bacteria,
cancer
cells,
normal
human
cells
are
discussed.
Excellent
performances
reported
different
literature.
Green
multimodal
imaging
have
potential
application
biomedical
replace
techniques
materials.
Functional
be
utilized
disciplines
biomaterials
with
ultimate
objective
effectively
detecting
treating
variety
diseases
higher
success
rate.
TrAC Trends in Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
172, P. 117596 - 117596
Published: Feb. 8, 2024
Diagnostic
devices
used
in
the
point-of-care
(POC)
today
play
a
critical
role
as
tools
to
provide
essential
medical
surveillance
data
and
ensure
that
patients
receive
appropriate
timely
care.
These
also
allow
self-analysis
by
patient,
increasing
therapeutic
adherence
well
reducing
pressure
on
clinical
structures.
The
development
of
new
diagnostic
tools,
therefore,
represents
significant
challenge
from
technological
point
view,
both
terms
overcoming
current
weaknesses
costs,
accuracy,
performance,
an
analytical
view
order
develop
are
operator-independent
possible.
Recent
breakthroughs
technologies
(such
cell
phone-dependent
technologies,
paper-based
procedures,
lab-on-a-chip
devices)
paving
way
for
next
generation
testing
(POCT).
Innovative
assay
devices,
efficient
reagent
storage
techniques,
required
POCT
technologies.
Nanomaterials
different
forms,
sizes,
compositions,
such
carbon
nanomaterials,
quantum
dots,
gold
silver
nanoparticles,
mesoporous
silica
metal-organic
frameworks
(MOFs),
have
been
created
characterized
recent
years.
Due
their
specific
physicochemical
properties,
MOF
nanoparticles
increasingly
being
improve
performance
simplify
techniques.
MOFs
colorimetric
or
electrochemical
carriers
plasmonic
biosensors
be
resistant
environmental
conditions.
This
review
will
discuss
detailed
2016
2023,
addition
chemical
synthesis
characterization
methods
related
uses
applications
MOF.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(26), P. 16752 - 16765
Published: June 20, 2024
Although
lateral
flow
immunochromatographic
assay
(LFIA)
is
an
effective
point-of-care
testing
technology,
it
still
cannot
achieve
broad-spectrum
and
ultrasensitive
detection
of
viruses.
Herein,
we
propose
a
multiplex
LFIA
platform
using
two-dimensional
graphene
oxide
(GO)-based
magnetic
fluorescent
nanofilm
(GF@DQD)
as
multifunctional
probe
4-aminophenylboronic
acid
(APBA)
recognition
molecule
for
viral
glycoprotein
detection.
GF@DQD-APBA
with
enhanced
magnetic/fluorescence
properties
universal
capture
ability
multiple
viruses
was
easily
prepared
through
the
electrostatic
adsorption
one
layer
density-controlled
Fe3O4
nanoparticles
(NPs)
thousands
small
CdSe/ZnS-MPA
quantum
dots
(QDs)
on
monolayer
GO
sheet
followed
by
chemical
coupling
APBA
QD
surface.
The
enabled
specific
determination
different
target
test
strip
arbitrary
combination
antibody-modified
strip,
thus
greatly
improving
efficiency
reducing
cost
difficulty
proposed
technique
can
simultaneously
sensitively
diagnose
three
newly
emerged
within
20
min
limits
down
to
pg/mL
level.
excellent
practicability
GF@DQD-APBA-LFIA
also
demonstrated
in
34
clinical
specimens
positive
SARS-CoV-2,
revealing
its
potential
epidemic
control
on-site
TrAC Trends in Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
176, P. 117722 - 117722
Published: April 30, 2024
Mycotoxins
are
responsible
for
several
diseases
in
human
and
animals
which
impose
huge
medical
economical
burdens
worldwide,
especially
low-income
countries.
Therefore,
many
countries
set
regulations
maximum
permissible
amounts
of
mycotoxins
food
that
need
detection
methods
to
monitor
the
mycotoxin
concentration.
Conventional
like
Enzyme‐linked
immunosorbent
assay
(ELISA),
high-performance
liquid
chromatography
(HPLC)
with
fluorescence
(HPLC-FLD),
chromatography-tandem
mass
spectrometry
(LC-MS/MS)
gas
(GC)
widely
used
quantitatively
mycotoxins.
However,
these
have
limitations
make
them
suitable
laboratories
factories,
but
cannot
be
regularly
daily
markets.
Thus,
pursuit
sensitive,
specific,
handheld,
low-cost
as
effective
elective
strategies
point-of-care
testing
(POCT)
has
gotten
much
consideration
recent
years.
POCT
is
one
ultimate
objectives
determination,
so
test
must
quick,
particular,
delicate,
open,
simple
used.
In
this
review,
after
a
brief
introduction
their
importance,
common
tools
advantages
disadvantages
discussed,
then
lateral
flow
(LFA)
systems
working
principles,
classifications,
method
explained.
Furthermore,
some
studies
regarding
development
LFA
detecting
types
innovations
LFAs'
design
techniques
overcoming
traditional
comprehensively
reviewed.
Various
utilized
extend
sensitivity
give
quantitative
sensing.
Utilizing
numerous
visualization
strategies,
utilizing
distinctive
labeled
reporters,
coordination
other
take
advantage
both
gadgets,
utilize
restrictive
membranes
upgrade
reagent
reactivity,
few
examined
literature
update
use
determination
mycotoxins,
covers.
The
period
time
from
2015
till
2023
based
on
data
bases.
