Nano-Micro Letters,
Год журнала:
2023,
Номер
16(1)
Опубликована: Ноя. 20, 2023
Massive
efforts
have
been
concentrated
on
the
advance
of
eminent
near-infrared
(NIR)
photothermal
materials
(PTMs)
in
NIR-II
window
(1000-1700
nm),
especially
organic
PTMs
because
their
intrinsic
biological
safety
compared
with
inorganic
PTMs.
However,
so
far,
only
a
few
NIR-II-responsive
was
explored,
and
conversion
efficiencies
(PCEs)
still
remain
relatively
low.
Herein,
donor-acceptor
conjugated
diradical
polymers
open-shell
characteristics
are
explored
for
synergistically
immunotherapy
metastatic
tumors
window.
By
employing
side-chain
regulation,
polymer
TTB-2
obvious
absorption
developed,
its
nanoparticles
realize
record-breaking
PCE
87.7%
upon
light
illustration.
In
vitro
vivo
experiments
demonstrate
that
show
good
tumor
photoablation
navigation
photoacoustic
imaging
window,
without
any
side-effect.
Moreover,
by
combining
PD-1
antibody,
pulmonary
metastasis
breast
cancer
is
high-effectively
prevented
efficient
photo-immunity
effect.
Thus,
this
study
explores
superior
theranostics
offering
new
horizon
developing
radical-characteristic
materials.
The
mutations
of
bacteria
due
to
the
excessive
use
antibiotics,
and
generation
antibiotic-resistant
have
made
development
new
antibacterial
compounds
a
necessity.
MXenes
emerged
as
biocompatible
transition
metal
carbide
structures
with
extensive
biomedical
applications.
This
is
related
MXenes'
unique
combination
properties,
including
multifarious
elemental
compositions,
2D-layered
structure,
large
surface
area,
abundant
terminations,
excellent
photothermal
photoelectronic
properties.
focus
this
review
application
MXenes,
which
has
attracted
attention
researchers
since
2016.
A
quick
overview
synthesis
strategies
provided
then
summarizes
effect
various
factors
(including
structural
optical
charges,
flake
size,
dispersibility)
on
biocidal
activity
MXenes.
main
mechanisms
for
deactivating
by
are
discussed
in
detail
rupturing
bacterial
membrane
sharp
edges
nanoflakes,
generating
reactive
oxygen
species
(ROS),
bacteria.
Hybridization
other
organic
inorganic
materials
can
result
improved
activities
different
applications
such
wound
dressings
water
purification.
Finally,
challenges
perspectives
MXene
nanomaterials
agents
presented.
Nano-Micro Letters,
Год журнала:
2023,
Номер
15(1)
Опубликована: Апрель 13, 2023
Abstract
Today,
self-healing
graphene-
and
MXene-based
composites
have
attracted
researchers
due
to
the
increase
in
durability
as
well
cost
reduction
long-time
applications.
Different
studies
focused
on
designing
novel
with
enhanced
sensitivity,
stretchability,
flexibility
improved
electrical
conductivity,
healing
efficacy,
mechanical
properties,
energy
conversion
efficacy.
These
properties
can
be
employed
field
of
wearable
sensors,
supercapacitors,
anticorrosive
coatings,
electromagnetic
interference
shielding,
electronic-skin,
soft
robotics,
etc.
However,
it
appears
that
more
explorations
are
still
needed
achieve
excellent
arbitrary
shape
adaptability,
suitable
adhesiveness,
ideal
durability,
high
immediate
responsibility,
outstanding
features.
Besides,
optimizing
reaction/synthesis
conditions
finding
strategies
for
functionalization/modification
crucial
aspects
should
comprehensively
investigated.
MXenes
graphene
exhibited
superior
electrochemical
abundant
surface
terminations
great
area,
which
important
evolve
biomedical
sensing
stretchability
criteria
need
their
future
Herein,
most
recent
advancements
pertaining
applications
deliberated,
focusing
challenges
perspectives.
Abstract
A
photoactivated
bone
scaffold
integrated
with
minimally
invasive
implantation
and
mild
thermal‐stimulation
capability
shows
great
promise
in
the
repair
regeneration
of
irregularly
damaged
tissues.
Developing
multifunctional
photothermal
biomaterials
that
can
simultaneously
serve
as
both
controllable
thermal
stimulators
biodegradable
engineering
scaffolds
for
immunomodulation,
infection
therapy,
impaired
remains
an
enormous
challenge.
Herein,
injectable
photocurable
hydrogel
therapeutic
platform
(AMAD/MP)
based
on
alginate
methacrylate,
alginate‐graft‐dopamine,
polydopamine
(PDA)‐functionalized
Ti3C2
MXene
(MXene@PDA)
nanosheets
is
rationally
designed
near‐infrared
(NIR)‐mediated
synergistic
osteogenesis,
bacterial
elimination.
The
optimized
AMAD/MP
exhibits
favorable
biocompatibility,
osteogenic
activity,
immunomodulatory
functions
vitro.
proper
immune
microenvironment
provided
by
could
further
modulate
balance
M1/M2
phenotypes
macrophages,
thereby
suppressing
reactive
oxygen
species‐induced
inflammatory
status.
Significantly,
this
stimulation
efficiently
attenuates
local
reactions
promotes
new
formation
without
addition
exogenous
cells,
cytokines,
or
growth
factors.
This
work
highlights
potential
application
advanced
providing
on‐demand
cues
tissue
regenerative
medicine.
Deleted Journal,
Год журнала:
2023,
Номер
2, С. e9120062 - e9120062
Опубликована: Март 8, 2023
Interfacial
solar
evaporation
(ISE)
is
a
promising
technology
to
relieve
worldwide
freshwater
shortages
owing
its
high
energy
conversion
efficiency
and
environmentally
sustainable
potential.
So
far,
many
innovative
materials
evaporators
have
been
proposed
applied
in
ISE
enable
highly
controllable
efficient
solar-to-thermal
conversion.
With
rational
design,
can
achieve
excellent
management
for
lowering
loss,
harvesting
extra
energy,
efficiently
utilizing
the
system
improve
production.
Beyond
that,
strategy
of
reducing
water
vaporization
enthalpy
by
introducing
molecular
engineering
water-state
regulation
has
also
demonstrated
as
an
effective
approach
boost
ISE.
Based
on
these,
this
article
discusses
nexus
two-dimensional
(2D)
three-dimensional
(3D)
separately
reviews
strategies
design
fabrication
systems.
The
summarized
work
offers
significant
perspectives
guiding
future
systems
with
management,
which
pave
pathways
practical
applications.
Materials & Design,
Год журнала:
2023,
Номер
233, С. 112231 - 112231
Опубликована: Авг. 9, 2023
Bacterial
infection
continues
to
be
one
of
the
biggest
threats
human
health.
The
therapeutic
effect
is
significantly
reduced
as
a
result
development
super-bacteria-resistant
bacteria
due
overuse
antibiotics
for
conventional
antimicrobial
treatment.
emergence
drug-resistant
makes
it
necessary
develop
new
treatments.
Following
successful
application
photothermal
therapy
in
field
oncology
treatment,
more
and
researchers
are
applying
treatments
achieving
important
results,
especially
treatment
bacterial
infections.
As
non-invasive
anti-infection
method,
has
advantages
broad-spectrum
properties,
short
period,
low
systemic
impact.
In
PTT,
efficacy
strongly
depends
on
different
laser
properties
choice
agents
(PTAs).
purpose
this
review
discuss
most
recent
developments
nanomaterials
that
antibacterial.
We
will
delve
into
principles
spectrum
PTAs
provide
summary
current
synthesis,
classification,
structural
features,
physicochemical
antibacterial
performance
research.
challenges
future
prospects
enhanced
cytotoxicity
investigated.
Biomaterials Research,
Год журнала:
2023,
Номер
27(1)
Опубликована: Фев. 9, 2023
Cancer
is
a
disease
caused
by
abnormal
cell
growth
that
spreads
through
other
parts
of
the
body
and
threatens
life
destroying
healthy
tissues.
Therefore,
numerous
techniques
have
been
employed
not
only
to
diagnose
monitor
progress
cancer
in
precise
manner
but
also
develop
appropriate
therapeutic
agents
with
enhanced
efficacy
safety
profiles.
In
this
regard,
molecularly
imprinted
polymers
(MIPs),
synthetic
receptors
recognize
targeted
molecules
high
affinity
selectivity,
intensively
investigated
as
one
most
attractive
biomaterials
for
theragnostic
approaches.
This
review
describes
diverse
synthesis
strategies
provide
rationale
behind
these
antibodies
provides
selective
overview
recent
vitro
vivo
targeting
biomarkers
diagnosis
applications.
Taken
together,
topics
discussed
concise
guidelines
development
novel
MIP-based
systems
more
precisely
promote
successful
treatment.
Molecularly
The
aim
