A Stable Open-Shell Conjugated Diradical Polymer with Ultra-High Photothermal Conversion Efficiency for NIR-II Photo-Immunotherapy of Metastatic Tumor DOI Creative Commons

Yijian Gao,

Ying Liu, Xiliang Li

и другие.

Nano-Micro Letters, Год журнала: 2023, Номер 16(1)

Опубликована: Ноя. 20, 2023

Massive efforts have been concentrated on the advance of eminent near-infrared (NIR) photothermal materials (PTMs) in NIR-II window (1000-1700 nm), especially organic PTMs because their intrinsic biological safety compared with inorganic PTMs. However, so far, only a few NIR-II-responsive was explored, and conversion efficiencies (PCEs) still remain relatively low. Herein, donor-acceptor conjugated diradical polymers open-shell characteristics are explored for synergistically immunotherapy metastatic tumors window. By employing side-chain regulation, polymer TTB-2 obvious absorption developed, its nanoparticles realize record-breaking PCE 87.7% upon light illustration. In vitro vivo experiments demonstrate that show good tumor photoablation navigation photoacoustic imaging window, without any side-effect. Moreover, by combining PD-1 antibody, pulmonary metastasis breast cancer is high-effectively prevented efficient photo-immunity effect. Thus, this study explores superior theranostics offering new horizon developing radical-characteristic materials.

Язык: Английский

MXenes Antibacterial Properties and Applications: A Review and Perspective DOI Creative Commons
Farzad Seidi, Ahmad Arabi Shamsabadi, Mostafa Dadashi Firouzjaei

и другие.

Small, Год журнала: 2023, Номер 19(14)

Опубликована: Янв. 5, 2023

The mutations of bacteria due to the excessive use antibiotics, and generation antibiotic-resistant have made development new antibacterial compounds a necessity. MXenes emerged as biocompatible transition metal carbide structures with extensive biomedical applications. This is related MXenes' unique combination properties, including multifarious elemental compositions, 2D-layered structure, large surface area, abundant terminations, excellent photothermal photoelectronic properties. focus this review application MXenes, which has attracted attention researchers since 2016. A quick overview synthesis strategies provided then summarizes effect various factors (including structural optical charges, flake size, dispersibility) on biocidal activity MXenes. main mechanisms for deactivating by are discussed in detail rupturing bacterial membrane sharp edges nanoflakes, generating reactive oxygen species (ROS), bacteria. Hybridization other organic inorganic materials can result improved activities different applications such wound dressings water purification. Finally, challenges perspectives MXene nanomaterials agents presented.

Язык: Английский

Процитировано

169

Self-Healing MXene- and Graphene-Based Composites: Properties and Applications DOI Creative Commons
Atefeh Zarepour, Sepideh Ahmadi, Navid Rabiee

и другие.

Nano-Micro Letters, Год журнала: 2023, Номер 15(1)

Опубликована: Апрель 13, 2023

Abstract Today, self-healing graphene- and MXene-based composites have attracted researchers due to the increase in durability as well cost reduction long-time applications. Different studies focused on designing novel with enhanced sensitivity, stretchability, flexibility improved electrical conductivity, healing efficacy, mechanical properties, energy conversion efficacy. These properties can be employed field of wearable sensors, supercapacitors, anticorrosive coatings, electromagnetic interference shielding, electronic-skin, soft robotics, etc. However, it appears that more explorations are still needed achieve excellent arbitrary shape adaptability, suitable adhesiveness, ideal durability, high immediate responsibility, outstanding features. Besides, optimizing reaction/synthesis conditions finding strategies for functionalization/modification crucial aspects should comprehensively investigated. MXenes graphene exhibited superior electrochemical abundant surface terminations great area, which important evolve biomedical sensing stretchability criteria need their future Herein, most recent advancements pertaining applications deliberated, focusing challenges perspectives.

Язык: Английский

Процитировано

86

Mild Photothermal‐Stimulation Based on Injectable and Photocurable Hydrogels Orchestrates Immunomodulation and Osteogenesis for High‐Performance Bone Regeneration DOI
Minhao Wu, Huifan Liu, Yufan Zhu

и другие.

Small, Год журнала: 2023, Номер 19(28)

Опубликована: Май 16, 2023

Abstract A photoactivated bone scaffold integrated with minimally invasive implantation and mild thermal‐stimulation capability shows great promise in the repair regeneration of irregularly damaged tissues. Developing multifunctional photothermal biomaterials that can simultaneously serve as both controllable thermal stimulators biodegradable engineering scaffolds for immunomodulation, infection therapy, impaired remains an enormous challenge. Herein, injectable photocurable hydrogel therapeutic platform (AMAD/MP) based on alginate methacrylate, alginate‐graft‐dopamine, polydopamine (PDA)‐functionalized Ti3C2 MXene (MXene@PDA) nanosheets is rationally designed near‐infrared (NIR)‐mediated synergistic osteogenesis, bacterial elimination. The optimized AMAD/MP exhibits favorable biocompatibility, osteogenic activity, immunomodulatory functions vitro. proper immune microenvironment provided by could further modulate balance M1/M2 phenotypes macrophages, thereby suppressing reactive oxygen species‐induced inflammatory status. Significantly, this stimulation efficiently attenuates local reactions promotes new formation without addition exogenous cells, cytokines, or growth factors. This work highlights potential application advanced providing on‐demand cues tissue regenerative medicine.

Язык: Английский

Процитировано

86

Recent strategies for constructing efficient interfacial solar evaporation systems DOI Creative Commons
Yida Wang, Junqing Hu, Yu Li

и другие.

Deleted Journal, Год журнала: 2023, Номер 2, С. e9120062 - e9120062

Опубликована: Март 8, 2023

Interfacial solar evaporation (ISE) is a promising technology to relieve worldwide freshwater shortages owing its high energy conversion efficiency and environmentally sustainable potential. So far, many innovative materials evaporators have been proposed applied in ISE enable highly controllable efficient solar-to-thermal conversion. With rational design, can achieve excellent management for lowering loss, harvesting extra energy, efficiently utilizing the system improve production. Beyond that, strategy of reducing water vaporization enthalpy by introducing molecular engineering water-state regulation has also demonstrated as an effective approach boost ISE. Based on these, this article discusses nexus two-dimensional (2D) three-dimensional (3D) separately reviews strategies design fabrication systems. The summarized work offers significant perspectives guiding future systems with management, which pave pathways practical applications.

Язык: Английский

Процитировано

85

Nanomaterials-based photothermal therapies for antibacterial applications DOI Creative Commons
Hao Liu, Fei Xing, Yuxi Zhou

и другие.

Materials & Design, Год журнала: 2023, Номер 233, С. 112231 - 112231

Опубликована: Авг. 9, 2023

Bacterial infection continues to be one of the biggest threats human health. The therapeutic effect is significantly reduced as a result development super-bacteria-resistant bacteria due overuse antibiotics for conventional antimicrobial treatment. emergence drug-resistant makes it necessary develop new treatments. Following successful application photothermal therapy in field oncology treatment, more and researchers are applying treatments achieving important results, especially treatment bacterial infections. As non-invasive anti-infection method, has advantages broad-spectrum properties, short period, low systemic impact. In PTT, efficacy strongly depends on different laser properties choice agents (PTAs). purpose this review discuss most recent developments nanomaterials that antibacterial. We will delve into principles spectrum PTAs provide summary current synthesis, classification, structural features, physicochemical antibacterial performance research. challenges future prospects enhanced cytotoxicity investigated.

Язык: Английский

Процитировано

83

MXenes: Versatile 2D materials with tailored surface chemistry and diverse applications DOI
Sunil Kumar, Nitu Kumari, Yongho Seo

и другие.

Journal of Energy Chemistry, Год журнала: 2023, Номер 90, С. 253 - 293

Опубликована: Дек. 5, 2023

Язык: Английский

Процитировано

63

Emerging 2D MXenes for antibacterial applications: Current status, challenges, and prospects DOI
Xiaojun He, Seyoung Koo, Enoch Obeng

и другие.

Coordination Chemistry Reviews, Год журнала: 2023, Номер 492, С. 215275 - 215275

Опубликована: Июнь 7, 2023

Язык: Английский

Процитировано

58

Facile fabrication of biomass chitosan-derived magnetic carbon aerogels as multifunctional and high-efficiency electromagnetic wave absorption materials DOI Open Access
Shijie Wang, Xue Zhang, Yunxiang Tang

и другие.

Carbon, Год журнала: 2023, Номер 216, С. 118528 - 118528

Опубликована: Окт. 15, 2023

Язык: Английский

Процитировано

50

Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications DOI Creative Commons
Min Seok Kang, Euni Cho,

Hye Eun Choi

и другие.

Biomaterials Research, Год журнала: 2023, Номер 27(1)

Опубликована: Фев. 9, 2023

Cancer is a disease caused by abnormal cell growth that spreads through other parts of the body and threatens life destroying healthy tissues. Therefore, numerous techniques have been employed not only to diagnose monitor progress cancer in precise manner but also develop appropriate therapeutic agents with enhanced efficacy safety profiles. In this regard, molecularly imprinted polymers (MIPs), synthetic receptors recognize targeted molecules high affinity selectivity, intensively investigated as one most attractive biomaterials for theragnostic approaches. This review describes diverse synthesis strategies provide rationale behind these antibodies provides selective overview recent vitro vivo targeting biomarkers diagnosis applications. Taken together, topics discussed concise guidelines development novel MIP-based systems more precisely promote successful treatment. Molecularly The aim

Язык: Английский

Процитировано

48

Photothermal controlled antibacterial Ta4C3Tx-AgNPs/nanocellulose bioplastic food packaging DOI

Xiaotong Wang,

Simin Xuan,

Keying Ding

и другие.

Food Chemistry, Год журнала: 2024, Номер 448, С. 139126 - 139126

Опубликована: Март 28, 2024

Язык: Английский

Процитировано

21