Recent progress in the 3D printing of microneedle patches for biomedical applications
Huan Liu,
Aminov Nail,
Decheng Meng
и другие.
International Journal of Pharmaceutics,
Год журнала:
2024,
Номер
unknown, С. 124995 - 124995
Опубликована: Ноя. 1, 2024
Язык: Английский
Polysaccharides as submucosal injection materials (SIMs) in endoscopic resection: A comprehensive review
Carbohydrate Polymers,
Год журнала:
2025,
Номер
355, С. 123360 - 123360
Опубликована: Фев. 5, 2025
Язык: Английский
Ozone exposure and increased risk of age-related macular degeneration: Evidence from nationwide cohort and toxicological studies
The Innovation,
Год журнала:
2025,
Номер
unknown, С. 100808 - 100808
Опубликована: Фев. 1, 2025
Язык: Английский
A gelatin microneedles featuring antibacterial and reactive oxygen species scavenging properties for treating Vibrio vulnificus-infected wounds
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 142640 - 142640
Опубликована: Март 1, 2025
Язык: Английский
Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring
Materials Today Bio,
Год журнала:
2025,
Номер
32, С. 101722 - 101722
Опубликована: Апрель 1, 2025
Topical
instilling
of
commercial
artificial
tears
(cAT,
containing
0.1
%
hyaluronic
acid)
is
widely
employed
to
alleviate
clinical
manifestations
mild
dry
eye
disease
(DED)
by
preventing
the
pathological
change
corneal
epithelium.
However,
it
showed
limited
therapy
effectiveness
on
heavy
DED
which
has
further
involved
stroma,
due
its
low
stroma-available
for
acid
(HA)
resulting
from
barrier
The
present
study
developed
a
new
microneedle-dosage
form
cAT
(cAT-MN).
This
cAT-MN
can
overstride
epithelium
and
act
as
long-lasting
protective
agent.
Compared
dosing
(4
times/day),
with
one
treatment
exerted
significantly
higher
therapeutic
effects
curbing
benzalkonium
chloride
(BAC)-induced
stroma
scaring
well
alleviating
symptoms
in
first
5-day
BAC
exposure;
whereas,
10-day
exposure.
To
expand
effects,
MNs
various
amounts
HA
were
prepared.
Thereinto,
HA(6
%)-MN
recovered
damage
healthy
levels,
could
be
attributed
adding
both
increasing
HA-delivery
enhancing
HA-permeation.
explores
drug-free
cure
disorders
expanded
indication,
promising
wide
use
ophthalmology.
Язык: Английский
Polymeric Microneedles for Biomedical Applications: Innovations in Transdermal Drug Delivery and Biosensing Technologies
Deleted Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 4, 2025
Язык: Английский
The effect and mechanism of enhanced photocatalytic fungicidal activity on nitrogen doped carbon dots-modified titanium dioxide
Carbon,
Год журнала:
2025,
Номер
unknown, С. 120314 - 120314
Опубликована: Апрель 1, 2025
Язык: Английский
Advances in Research of Hydrogel Microneedle-Based Delivery Systems for Disease Treatment
Pharmaceutics,
Год журнала:
2024,
Номер
16(12), С. 1571 - 1571
Опубликована: Дек. 9, 2024
Microneedles
(MNs),
composed
of
multiple
micron-scale
needle-like
structures
attached
to
a
base,
offer
minimally
invasive
approach
for
transdermal
drug
delivery
by
penetrating
the
stratum
corneum
and
delivering
therapeutic
agents
directly
epidermis
or
dermis.
Hydrogel
microneedles
(HMNs)
stand
out
among
various
MN
types
due
their
excellent
biocompatibility,
high
drug-loading
capacity,
tunable
drug-release
properties.
This
review
systematically
examines
matrix
materials
fabrication
methods
HMN
systems,
highlighting
advancements
in
natural
synthetic
polymers,
explores
applications
treating
conditions
such
as
wound
healing,
hair
loss,
cardiovascular
diseases,
cancer.
Furthermore,
potential
HMNs
disease
diagnostics
is
discussed.
The
identifies
key
challenges,
including
limited
mechanical
strength,
efficiency,
lack
standardization,
while
proposing
strategies
overcome
these
issues.
With
integration
intelligent
design
enhanced
control
over
dosage
safety,
are
poised
revolutionize
expand
personalized
medicine.
Язык: Английский