Geriatrics,
Год журнала:
2024,
Номер
9(6), С. 168 - 168
Опубликована: Дек. 22, 2024
Background/Objectives:
The
annual
incidence
of
falls
is
high
in
older
adults
with
impaired
cognitive
function
and
dementia,
injuries
have
a
detrimental
effect
on
disability-adjusted
life-years
public
health
spending.
In
this
registry-based
study,
fall
characteristics
the
fallers
were
explored
large
population
impairment.
Methods:
NorCog,
“The
Norwegian
Registry
Persons
Assessed
for
Cognitive
Symptoms”,
national
research
quality
registry
biomaterial
collection.
This
study
included
9525
persons
from
who
had
answered
question
about
falls.
Fall
was
studied,
non-fallers
compared.
Results:
3774/9525
(39.6%).
varied
between
types
22.4%
debut
Alzheimer’s
disease
before
65
years
age
to
55.3%
vascular
dementia
increasing
degrees
A
wide
range
personal
characteristics,
symptoms,
signs,
laboratory
tests,
physical,
psychological,
tests
differed
non-fallers,
most
disfavour
fallers.
Age,
reduced
Personal
Activities
Daily
Living,
gait
speed,
delayed
recall,
use
walking
aid,
depression
independent
predictors
Conclusions:
Among
cognitively
history
falls,
frailty
an
predictor
Neither
type
nor
degree
impairment
Prevention
by
physical
training
social
activity
may
be
important
mitigating
risk
among
cognition.
Journal of the American Geriatrics Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 5, 2025
ABSTRACT
Objective
The
primary
objective
of
this
study
was
to
assess
the
prescribing
patterns
long
acting
injectable
(LAI)
antipsychotics
in
an
older
adult
population.
Secondary
objectives
were
determine
if
there
differences
treatment
discontinuation
rates
between
different
LAI
agents
and
race/ethnicity.
Methods
Merative
MarketScan
Multi‐State
Medicaid
Databases
(2017–2021)
used
identify
patients
65
years
or
who
prescribed
a
antipsychotic.
Pharmacy
claims
for
referenced
via
National
Drug
Code
(NDC)
by
brand/generic
name
dose.
International
Classification
Diseases,
10th
edition
(ICD‐10)
codes
adults
diagnosed
with
schizophrenia,
schizotypal
schizoaffective
disorders.
Those
dementia
related
disorders
censored.
Conditional
associations
race/ethnicity
generation
investigated
using
logistic
regression
controlling
age,
sex,
health
plan.
Cox
proportional
hazard
compare
distribution
time
until
among
across
antipsychotics.
Results
A
total
526
(59%
female)
average
age
70.4
±
5.5
met
inclusion
analysis.
most
commonly
included
paliperidone
palmitate‐1
month
formulation
(~35%),
haloperidol
decanoate
(~24%),
risperidone
microspheres
(~15%).
Overall,
approximately
32%
received
first‐generation
68%
second
Blacks
(
n
=
204)
more
often
than
Whites
283);
(OR:
1.74,
95%
[1.18,
2.56],
p
<
0.01).
When
race/ethnicity,
showed
earlier
compared
second‐generation
(HR:
2.12,
CI
[1.45,
3.10],
0.001).
Conclusions
significantly
Furthermore,
at
higher
rate
Whites,
which
may
contribute
poorer
outcomes.
Futures
studies
are
needed
establish
causal
relationship.
European Geriatric Medicine,
Год журнала:
2023,
Номер
14(4), С. 649 - 658
Опубликована: Июль 15, 2023
Falls
prevention
and
management
in
older
adults
is
a
critical
global
challenge.
One
of
the
key
risk
factors
for
falls
use
certain
medications.
Therefore,
to
prevent
medication-related
falls,
following
recommended
recent
World
Guidelines
Prevention
Management:
(1)
assess
fall
history
before
prescribing
potential
fall-risk-increasing
drugs
(FRIDs),
(2)
validated,
structured
screening
assessment
tool
identify
FRIDs
when
performing
medication
review,
(3)
include
review
appropriate
deprescribing
as
part
multifactorial
intervention,
(4)
long-term
care
residents,
if
intervention
cannot
be
conducted
due
limited
resources,
strategy
should
still
always
FRIDs.In
present
statement
paper,
working
group
on
Management,
collaboration
with
European
Geriatric
Medicine
Society
(EuGMS)
Task
Finish
FRIDs,
outlines
its
position
how
implement
execute
these
recommendations
clinical
practice.Preferably,
comprehensive
geriatric
produce
personalized
patient-centered
assessment.
Furthermore,
major
pitfall
published
studies
so
far
suboptimal
implementation
deprescribing.
For
future,
it
important
focus
gaining
which
elements
determine
successful
apply
concepts
science
decrease
gap
between
research
practice.
Drug Safety,
Год журнала:
2024,
Номер
47(11), С. 1061 - 1074
Опубликована: Июль 11, 2024
The
growing
complexity
of
geriatric
pharmacotherapy
necessitates
effective
tools
for
mitigating
the
risks
associated
with
polypharmacy.
Screening
Tool
Older
Persons'
Potentially
Inappropriate
Prescriptions
(STOPP)/Screening
to
Alert
doctors
Right
Treatment
(START)
criteria
have
been
instrumental
in
optimizing
medication
management
among
older
adults.
Despite
their
large
adoption
improving
reduction
potentially
inappropriate
medications
(PIM)
and
patient
outcomes,
implementation
STOPP/START
faces
notable
challenges.
extensive
number
latest
version
time
constraints
primary
care
pose
practical
difficulties,
particularly
settings
a
high
patients.
This
paper
critically
evaluates
challenges
evolving
implications
applying
third
across
various
clinical
settings,
focusing
on
European
healthcare
context.
Utilizing
"Questions
&
Answers"
format,
it
examines
criteria's
discusses
relevant
suitability
potential
adaptations
address
diverse
needs
different
environments.
By
emphasizing
these
aspects,
this
aims
contribute
ongoing
discourse
enhancing
safety
efficacy
population,
promote
more
person-centred
an
aging
society.
Therapeutic Advances in Neurological Disorders,
Год журнала:
2024,
Номер
17
Опубликована: Янв. 1, 2024
Delirium
is
a
common
complication
in
acute
stroke
patients,
occurring
15-35%
of
all
unit
admissions
and
associated
with
prolonged
hospital
stay
poor
post-stroke
prognosis.
Managing
delirium
patients
necessitates
an
intensive
multiprofessional
therapeutic
approach,
placing
significant
burden
on
healthcare
staff.
However,
dedicated
practical
recommendations
for
management
developed
the
population
are
lacking.
For
this
purpose,
Austrian
Stroke
Society,
cooperation
Society
Neurology,
Neurorehabilitation,
Psychiatry,
Psychotherapy,
Psychosomatics
has
formulated
evidence-based
position
paper
addressing
patients.
The
outlines
three
pillars
care
delirium:
(a)
Key
aspects
