Falls in Persons with Cognitive Impairment—Incidence and Characteristics of the Fallers DOI Creative Commons
Per G. Farup, Knut Hestad, Knut Engedal

et al.

Geriatrics, Journal Year: 2024, Volume and Issue: 9(6), P. 168 - 168

Published: Dec. 22, 2024

Background/Objectives: The annual incidence of falls is high in older adults with impaired cognitive function and dementia, injuries have a detrimental effect on disability-adjusted life-years public health spending. In this registry-based study, fall characteristics the fallers were explored large population impairment. Methods: NorCog, “The Norwegian Registry Persons Assessed for Cognitive Symptoms”, national research quality registry biomaterial collection. This study included 9525 persons from who had answered question about falls. Fall was studied, non-fallers compared. Results: 3774/9525 (39.6%). varied between types 22.4% debut Alzheimer’s disease before 65 years age to 55.3% vascular dementia increasing degrees A wide range personal characteristics, symptoms, signs, laboratory tests, physical, psychological, tests differed non-fallers, most disfavour fallers. Age, reduced Personal Activities Daily Living, gait speed, delayed recall, use walking aid, depression independent predictors Conclusions: Among cognitively history falls, frailty an predictor Neither type nor degree impairment Prevention by physical training social activity may be important mitigating risk among cognition.

Language: Английский

Use and Discontinuation Rates of Long‐Acting Injectable Antipsychotics Between Race/Ethnicity in Older Adults Using Medicaid Databases DOI Creative Commons

Catherine Cassara,

Jianing Xu, Daniel B. Hall

et al.

Journal of the American Geriatrics Society, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

ABSTRACT Objective The primary objective of this study was to assess the prescribing patterns long acting injectable (LAI) antipsychotics in an older adult population. Secondary objectives were determine if there differences treatment discontinuation rates between different LAI agents and race/ethnicity. Methods Merative MarketScan Multi‐State Medicaid Databases (2017–2021) used identify patients 65 years or who prescribed a antipsychotic. Pharmacy claims for referenced via National Drug Code (NDC) by brand/generic name dose. International Classification Diseases, 10th edition (ICD‐10) codes adults diagnosed with schizophrenia, schizotypal schizoaffective disorders. Those dementia related disorders censored. Conditional associations race/ethnicity generation investigated using logistic regression controlling age, sex, health plan. Cox proportional hazard compare distribution time until among across antipsychotics. Results A total 526 (59% female) average age 70.4 ± 5.5 met inclusion analysis. most commonly included paliperidone palmitate‐1 month formulation (~35%), haloperidol decanoate (~24%), risperidone microspheres (~15%). Overall, approximately 32% received first‐generation 68% second Blacks ( n = 204) more often than Whites 283); (OR: 1.74, 95% [1.18, 2.56], p < 0.01). When race/ethnicity, showed earlier compared second‐generation (HR: 2.12, CI [1.45, 3.10], 0.001). Conclusions significantly Furthermore, at higher rate Whites, which may contribute poorer outcomes. Futures studies are needed establish causal relationship.

Language: Английский

Citations

1

European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation DOI Creative Commons
Nathalie van der Velde, Lotta J. Seppälä, Sirpa Hartikainen

et al.

European Geriatric Medicine, Journal Year: 2023, Volume and Issue: 14(4), P. 649 - 658

Published: July 15, 2023

Falls prevention and management in older adults is a critical global challenge. One of the key risk factors for falls use certain medications. Therefore, to prevent medication-related falls, following recommended recent World Guidelines Prevention Management: (1) assess fall history before prescribing potential fall-risk-increasing drugs (FRIDs), (2) validated, structured screening assessment tool identify FRIDs when performing medication review, (3) include review appropriate deprescribing as part multifactorial intervention, (4) long-term care residents, if intervention cannot be conducted due limited resources, strategy should still always FRIDs.In present statement paper, working group on Management, collaboration with European Geriatric Medicine Society (EuGMS) Task Finish FRIDs, outlines its position how implement execute these recommendations clinical practice.Preferably, comprehensive geriatric produce personalized patient-centered assessment. Furthermore, major pitfall published studies so far suboptimal implementation deprescribing. For future, it important focus gaining which elements determine successful apply concepts science decrease gap between research practice.

Language: Английский

Citations

11

Código delirium DOI
Marta Martínez‐García,

Brian Dax Vásquez-Brolen,

Fátima Brañas

et al.

Revista Española de Geriatría y Gerontología, Journal Year: 2025, Volume and Issue: 60(4), P. 101659 - 101659

Published: April 15, 2025

Language: Английский

Citations

0

Antipsychotics and dietary interventions: pharmacodynamics, pharmacokinetics and synergisms in therapy DOI Creative Commons
Cristiana Perrotta, Carla Carnovale, Marco Pozzi

et al.

Pharmacological Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 100061 - 100061

Published: April 1, 2025

Language: Английский

Citations

0

Exploring Antipsychotic Use for Delirium Management in Adults in Hospital, Sub-Acute Rehabilitation and Aged Care Settings: A Systematic Literature Review DOI Creative Commons
Emily Tomlinson, Linda Schnitker, Penelope Casey

et al.

Drugs & Aging, Journal Year: 2024, Volume and Issue: 41(6), P. 455 - 486

Published: June 1, 2024

Language: Английский

Citations

2

A Longitudinal Study of the Use and Effects of Fall-Risk-Increasing Drugs in Residential Aged Care DOI Creative Commons
Nasir Wabe, Guogui Huang, S. Sandun M. Silva

et al.

Journal of the American Medical Directors Association, Journal Year: 2024, Volume and Issue: 25(8), P. 105074 - 105074

Published: June 12, 2024

Language: Английский

Citations

2

Adopting STOPP/START Criteria Version 3 in Clinical Practice: A Q&A Guide for Healthcare Professionals DOI Creative Commons
Carlotta Lunghi, Marco Domenicali,

Stefano Vertullo

et al.

Drug Safety, Journal Year: 2024, Volume and Issue: 47(11), P. 1061 - 1074

Published: July 11, 2024

The growing complexity of geriatric pharmacotherapy necessitates effective tools for mitigating the risks associated with polypharmacy. Screening Tool Older Persons' Potentially Inappropriate Prescriptions (STOPP)/Screening to Alert doctors Right Treatment (START) criteria have been instrumental in optimizing medication management among older adults. Despite their large adoption improving reduction potentially inappropriate medications (PIM) and patient outcomes, implementation STOPP/START faces notable challenges. extensive number latest version time constraints primary care pose practical difficulties, particularly settings a high patients. This paper critically evaluates challenges evolving implications applying third across various clinical settings, focusing on European healthcare context. Utilizing "Questions & Answers" format, it examines criteria's discusses relevant suitability potential adaptations address diverse needs different environments. By emphasizing these aspects, this aims contribute ongoing discourse enhancing safety efficacy population, promote more person-centred an aging society.

Language: Английский

Citations

2

A themed journal issue on (de)prescribing dilemmas in older, multimorbid adults with increased fall risk DOI Open Access
Eveline P. van Poelgeest, Nathalie van der Velde

European Geriatric Medicine, Journal Year: 2023, Volume and Issue: 14(4), P. 645 - 648

Published: Aug. 5, 2023

Language: Английский

Citations

2

Antipsychotics Use in the Elderly DOI

Leana Pustam,

Abigail Weisse,

Ram Bishnoi

et al.

Advances in Psychiatry and Behavioral Health, Journal Year: 2024, Volume and Issue: 4(1), P. 167 - 175

Published: June 27, 2024

Language: Английский

Citations

0

Management of delirium in acute stroke patients: a position paper by the Austrian Stroke Society on prevention, diagnosis, and treatment DOI Creative Commons
Markus Kneihsl,

Natalie Berger,

Stefan Sumerauer

et al.

Therapeutic Advances in Neurological Disorders, Journal Year: 2024, Volume and Issue: 17

Published: Jan. 1, 2024

Delirium is a common complication in acute stroke patients, occurring 15-35% of all unit admissions and associated with prolonged hospital stay poor post-stroke prognosis. Managing delirium patients necessitates an intensive multiprofessional therapeutic approach, placing significant burden on healthcare staff. However, dedicated practical recommendations for management developed the population are lacking. For this purpose, Austrian Stroke Society, cooperation Society Neurology, Neurorehabilitation, Psychiatry, Psychotherapy, Psychosomatics has formulated evidence-based position paper addressing patients. The outlines three pillars care delirium: (a) Key aspects

Language: Английский

Citations

0