Review on phyto-extract methodologies for procuring ZnO NPs and its pharmacological functionalities
Process Biochemistry,
Год журнала:
2024,
Номер
147, С. 186 - 212
Опубликована: Авг. 25, 2024
Язык: Английский
Oxidative stress-induced cytotoxicity of HCC2998 colon carcinoma cells by ZnO nanoparticles synthesized from Calophyllum teysmannii
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Дек. 4, 2024
The
field
of
green
synthesis,
namely
using
plant
extracts
for
the
production
metal
nanoparticles,
is
rapidly
gaining
traction.
Therefore,
this
study
investigated
process
producing
zinc
oxide
nanoparticles
(ZnO
NPs)
a
water-based
extract
derived
from
stem
bark
Calophyllum
teysmannii.
Notably,
first
documented
utilization
particular
source.
presence
distinct
Ultraviolet-Visible
(UV-Vis)
absorption
peak
at
372
nm
provided
evidence
creation
ZnO
nanoparticles.
X-ray
Diffractometer
(XRD)
and
Field
Emission
Scanning
Electron
Microscopy
(FESEM)
investigations
indicated
that
exhibited
sizes
ranging
31.5
to
59.9
had
spherical
morphologies.
Energy
Dispersive
(EDX)
analysis
verified
elemental
composition
whereas
Fourier
Transform
Infrared
(FTIR)
spectra
showed
clear
peaks,
demonstrating
their
production.
FTIR
examination
C.
teysmannii
revealed
peaks
around
3370
cm−
1,
indicating
phenolic
compounds.
These
chemicals
are
likely
responsible
reduction
stabilization
NPs.
high-resolution
Photoelectron
Spectroscopy
(XPS)
clearly
separate
corresponding
Zn
2p
O
1s,
providing
confirmation
chemical
states
bonding
contexts.
Raman
425
cm⁻¹,
confirming
wurtzite
structure.
harmful
effects
on
HCC2998
(a
kind
human
colon
cancer)
Vero
type
monkey
kidney
epithelial)
cells
were
evaluated
3-(4,
5-dimethylthiazolyl-2)-2,
5-diphenyltetrazolium
bromide
(MTT),
dichlorodihydrofluorescein
diacetate
(DCFH-DA),
boron-Dipyrromethene
(BODIPY)
assays.
cancer
underwent
cell
death
due
oxidative
stress
in
dose-dependent
manner,
as
confirmed
by
microscopic
flow
cytometry
investigations.
Язык: Английский
Biogenic formulation and characterisation of Zinc oxide nanoparticles for photocatalytic degradation of methyl violet, rhodamine b, and blue 19-dyes and antibacterial & antioxidant activities
Valikala Viswanath,
Jayaprakash Meena,
E. Manikandamoorthy
и другие.
International Journal of Environmental & Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 19
Опубликована: Фев. 10, 2025
The
green
synthesis
of
zinc
oxide
(ZnO)
nanomaterials
is
increasingly
recognised
in
due
to
their
minimal
toxicity,
high
biocompatibility,
and
simple
fabrication
methods.
This
study
presents
the
eco-friendly
ZnO
nanoparticles
(ZnONPs)
using
Lilium
lancifolium
floral
extract
as
a
bio-reductant.
Comprehensive
physicochemical
characterisation,
including
spectroscopic
microscopic
analyses,
was
conducted
elucidate
nanoparticles'
structural
morphological
properties.
ZnONPs
displayed
spherical
hexagonal
morphologies,
consisting
49.34%
oxygen
50.66%
zinc.
Zeta
potential
measurements
indicated
negative
surface
charge,
BET
disclosed
specific
area
35
m2/g,
an
average
pore
size
~
25
nm,
volume
0.74
cm3/g.
Dynamic
light
scattering
(DLS)
revealed
particle
27
nm
polydispersity
index
(PDI)
0.332.
antioxidant
capacity
ZnONPs,
assessed
through
DPPH
radical
scavenging
assays,
showed
activity
ranging
from
39.2%
71.2%,
with
IC50
47.2
µg/mL.
performance
surpassed
(72.3
µg/mL)
comparable
ascorbic
acid
(IC50
=
37.4
µg/mL).
Photocatalytic
degradation
studies
on
methyl
violet
(MV),
Rhodamine
B
(RhB),
reactive
blue
19
(RBBR)
dyes
followed
pseudo-first-order
kinetics
adhered
Langmuir-Hinshelwood
adsorption
models.
Additionally,
lipid
peroxidation
inhibition
assays
demonstrated
both
preventing
peroxidation,
indicating
promising
antimicrobial
properties
for
combating
bacterial
infections.
Язык: Английский
Biosynthesis and Characterization of Mn3O4 Nanoparticles Using Bixa orellana and Nerium oleander Leaf Extracts at Low Temperature and Neutral pH
Crystals,
Год журнала:
2025,
Номер
15(3), С. 226 - 226
Опубликована: Фев. 27, 2025
Mn3O4
nanoparticles
have
been
synthesized
using
alcoholic
extracts,
at
pH
=
7
and
low
temperature
(60
°C),
from
different
masses
(1.00,
3.00,
5.00,
7.00
g)
of
fresh
leaves
Nerium
oleander
Bixa
orellana,
without
additional
heat
treatment.
Appropriate
techniques
were
used
to
identify
the
secondary
metabolites
extracts
evaluate
structural,
optical,
chemical
properties
nanoparticles.
The
XRD
results
confirmed
formation
with
crystallite
size
in
5−8
nm
range,
more
notable
effects
on
crystallinity
obtained
B.
orellana
extracts.
greatest
effect
bandgap
was
observed
N.
Raman
spectra
phonon
confinement,
PL
spectra,
emission
bands
associated
structural
defects,
such
as
oxygen
vacancies,
observed.
In
FTIR
main
identified,
whose
intensity
decreased
concentration
extract
other
functional
groups
increased.
TEM
images
showed
spherical
7.81
(N1)
7.94
(B1)
average
diameters.
appropriate
than
that
for
synthesis
under
conditions
used.
Язык: Английский
Electrospun Polycaprolactone–Gelatin Fibrils Enabled 3D Hydrogel Microcapsules for Biomedical Applications
Journal of Functional Biomaterials,
Год журнала:
2025,
Номер
16(3), С. 85 - 85
Опубликована: Март 2, 2025
Microcapsules
provide
a
microenvironment
by
improving
the
protection
and
delivery
of
cells
drugs
to
specific
tissue
areas,
promoting
cell
integration
regeneration.
Effective
microcapsules
must
not
only
be
permeable
for
micronutrient
diffusion
but
mechanically
stable.
Alginate
hydrogel
is
one
commonly
used
biomaterials
fabricating
due
its
gel-forming
ability
low
toxicity.
However,
mechanical
instability,
inertness,
excessive
porosity
have
impeded
use.
Embedding
nanofibrils
in
alginate
improves
their
biological
properties.
In
this
research,
electrospun
composite
nanofibers
PCL–gelatin
(PG)
were
first
fabricated,
characterized,
cryoground.
The
filtered
cryoground
powder
solution
was
mixed
with
through
electrospray,
fabricated
into
microcapsules.
Parameters
such
as
flow
rate,
voltage,
composition,
which
are
critical
electrostatic
encapsulation
process,
optimized.
further
immersed
different
solvent
environments
(DI
water,
complete
media,
PBS),
observed
compared
morphology,
size
distribution,
stability
average
diameters
PG
ranged
between
0.2
2
μm,
an
58
73%.
varied
300
900
depending
on
environment.
Overall,
results
showed
improved
3D
network
suitable
biomedical
applications.
Язык: Английский
Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities
Journal of Chemistry,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
The
present
research
involves
a
green
synthesis
of
silver
and
zinc
oxide
nanoparticles
using
an
aqueous
extract
Polystichum
lentum
comparison
bioactivities.
Phenolics,
flavonoids,
alkaloids,
steroids,
saponins
were
in
the
extract.
highest
TPC
TFC
found
ethanol
with
124.93
±
9.36
mg
GAE/g
28.73
1.98
QE/g.
formation
Ag
ZnO
NPs
was
confirmed
by
appearance
peaks
at
421
nm
362
UV‐visible
spectra.
involvement
plant
secondary
metabolites
nanoparticle
indicated
shifts
peak
positions
intensities
FTIR
SEM
XRD
analyses
established
spherical
morphology
(average
size
61.33
15.31
nm)
FCC
crystal
structure
for
hexagonal
to
round
97.20
12.92
wurtzite
NPs.
EDX
analysis
revealed
elemental
composition
nanoparticles.
IC
50
values
51.95
3.11
83.79
6.63
μ
g/mL
DPPH
assay
significantly
higher
than
32.07
1.03
6.53
1.57
methanol
extracts.
showed
comparatively
ZOI
14
16
mm
against
Shigella
sonnei
Klebsiella
pneumoniae.
It
also
displayed
lowest
MIC
MBC
3.125
6.25
mg/mL
Staphylococcus
aureus
pneumoniae
.
exhibit
potent
cytotoxicity
76.82
1.67
cervical
cancer
cell
lines.
Both
mildly
toxic
towards
brine
shrimp
nauplii
LC
being
661.80
64.21
In
conclusion,
findings
study
demonstrate
high
antioxidant,
antibacterial,
anticancer
activities
synthesized
Язык: Английский
In silico molecular docking and ADMET prediction of biogenic zinc oxide nanoparticles: characterization, and in vitro antimicrobial and photocatalytic activity
RSC Advances,
Год журнала:
2024,
Номер
14(49), С. 36209 - 36225
Опубликована: Янв. 1, 2024
A
facile
green
route
to
synthesize
zinc
oxide
nanoparticles
using
watermelon
rind
extract
with
antimicrobial
and
photocatalytic
potential.
Язык: Английский
Biosynthesis of Zinc Oxide Nanoparticles Using Garlic Peel Extract and Their Antibacterial Potential
Microbiology Research,
Год журнала:
2024,
Номер
15(3), С. 1655 - 1669
Опубликована: Авг. 23, 2024
Zinc
oxide
nanoparticles
(ZnO
NPs)
have
gathered
interest
because
of
their
unique
characteristics
and
potential
applications.
In
the
current
work,
ZnO
NPs
underwent
an
eco-friendly
biosynthesis
process
using
garlic
peel
extract.
The
biosynthesized
were
characterized
different
analyses
including
Ultraviolet-visible
(UV-vis)
spectroscopy,
scanning
electron
microscopy
(SEM),
energy-dispersive
X-ray
spectroscopy
(EDS),
dynamic
light
scattering
(DLS),
Fourier
transform
infrared
(FTIR).
produced
exhibited
a
UV–vis
spectrum
absorption
peak
at
365
nm,
thus
indicating
formation
NPs.
SEM
showed
that
had
irregular
surface
morphological
shape
with
average
size
17
according
to
DLS
analysis.
Based
on
FTIR
findings,
bioactive
functional
groups
responsible
for
stabilizing
capping
ZnO-NPs
confirmed.
2,2-diphenyl-1-picrylhydrazyl
(DPPH)
radical-scavenging
activity
antimicrobial
activities
against
Gram-positive
(Bacillus
cereus)
Gram-negative
bacteria
(Klebsiella
pneumonia).
Therefore,
plant-mediated
ZnNPs
can
be
considered
promising
candidate
as
antioxidant
agent
pathogenic
microbes
found
in
areas
such
food
safety
agriculture.
Through
utilization
bioinformatics,
we
identified
six
targets
drug
development
K.
pneumonia
B.
cereus,
along
corresponding
interacting
residues
zinc
nanoparticles.
Additionally,
our
research
revealed
binding
capabilities
sulfiredoxin
domain
located
specific
pneumonia,
crucial
mechanism
repair
bacterial
cells
under
oxidative
stress.
Язык: Английский
Green Essence of Plant Resources Capped Zinc Oxide Nanoparticles: Renewable Distinctions, Size‐Shape‐Modulated Physicochemical Diversity and Emerging Biomedical‐Environmental Usefulness
Particle & Particle Systems Characterization,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 15, 2024
Abstract
The
natural
essence,
biocompatibility,
and
pleiotropic
functioning
of
plant
polyphenols
have
swiftly
emerged
as
integrated
assets
for
biomedical
environmental
applications
resources
capped
ZnO
NPs.
Simultaneous
reducing
cum
capping
abilities,
synergistic
edible
prospects,
precursor‐plant
extract
stoichiometry‐driven
robust
size‐shape
modulation
are
the
major
encouragements
being
explored
increasing
recent
interest
in
biomedical‐environmental
extracts
(PEs)
structure‐function
dynamics
from
leaves,
roots,
fruits,
seeds,
whole
plants
sum
up
multifaceted
polyphenols‐capped
Recent
resources'
utility
NPs
mandates
discussing
correlative
mechanisms
sustainable
future
insights.
PEs
drug
carriers
sensing
agents
significantly
moderate
toxic
chemotherapeutic
intake
via
enhanced
tumor
cell
internalization,
aided
by
immune‐modulating
actions
constituent
phytochemicals.
On
front,
antioxidant
features
make
them
potent
degrading
degradation
persisting
effluents.
Keeping
above
aspects
mind,
this
review
article
focuses
on
underlying
remediation
made
This
would
augment
awareness
consolidating
understanding
predictive
mechanistic
controls.
Язык: Английский