Green Essence of Plant Resources Capped Zinc Oxide Nanoparticles: Renewable Distinctions, Size‐Shape‐Modulated Physicochemical Diversity and Emerging Biomedical‐Environmental Usefulness DOI Open Access
Parth Malik, Ruma Rani, Sharjeel Ahmed Khan

et al.

Particle & Particle Systems Characterization, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Abstract The natural essence, biocompatibility, and pleiotropic functioning of plant polyphenols have swiftly emerged as integrated assets for biomedical environmental applications resources capped ZnO NPs. Simultaneous reducing cum capping abilities, synergistic edible prospects, precursor‐plant extract stoichiometry‐driven robust size‐shape modulation are the major encouragements being explored increasing recent interest in biomedical‐environmental extracts (PEs) structure‐function dynamics from leaves, roots, fruits, seeds, whole plants sum up multifaceted polyphenols‐capped Recent resources' utility NPs mandates discussing correlative mechanisms sustainable future insights. PEs drug carriers sensing agents significantly moderate toxic chemotherapeutic intake via enhanced tumor cell internalization, aided by immune‐modulating actions constituent phytochemicals. On front, antioxidant features make them potent degrading degradation persisting effluents. Keeping above aspects mind, this review article focuses on underlying remediation made This would augment awareness consolidating understanding predictive mechanistic controls.

Language: Английский

Review on phyto-extract methodologies for procuring ZnO NPs and its pharmacological functionalities DOI

Manoharan Janani,

Dhivya Viswanathan, Saravanan Pandiaraj

et al.

Process Biochemistry, Journal Year: 2024, Volume and Issue: 147, P. 186 - 212

Published: Aug. 25, 2024

Language: Английский

Citations

4
Oxidative stress-induced cytotoxicity of HCC2998 colon carcinoma cells by ZnO nanoparticles synthesized from Calophyllum teysmannii DOI Creative Commons
Hemaroopini Subramaniam, Chan Lim, Lai‐Hock Tey

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 4, 2024

The field of green synthesis, namely using plant extracts for the production metal nanoparticles, is rapidly gaining traction. Therefore, this study investigated process producing zinc oxide nanoparticles (ZnO NPs) a water-based extract derived from stem bark Calophyllum teysmannii. Notably, first documented utilization particular source. presence distinct Ultraviolet-Visible (UV-Vis) absorption peak at 372 nm provided evidence creation ZnO nanoparticles. X-ray Diffractometer (XRD) and Field Emission Scanning Electron Microscopy (FESEM) investigations indicated that exhibited sizes ranging 31.5 to 59.9 had spherical morphologies. Energy Dispersive (EDX) analysis verified elemental composition whereas Fourier Transform Infrared (FTIR) spectra showed clear peaks, demonstrating their production. FTIR examination C. teysmannii revealed peaks around 3370 cm− 1, indicating phenolic compounds. These chemicals are likely responsible reduction stabilization NPs. high-resolution Photoelectron Spectroscopy (XPS) clearly separate corresponding Zn 2p O 1s, providing confirmation chemical states bonding contexts. Raman 425 cm⁻¹, confirming wurtzite structure. harmful effects on HCC2998 (a kind human colon cancer) Vero type monkey kidney epithelial) cells were evaluated 3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT), dichlorodihydrofluorescein diacetate (DCFH-DA), boron-Dipyrromethene (BODIPY) assays. cancer underwent cell death due oxidative stress in dose-dependent manner, as confirmed by microscopic flow cytometry investigations.

Language: Английский

Citations

4
Biogenic formulation and characterisation of Zinc oxide nanoparticles for photocatalytic degradation of methyl violet, rhodamine b, and blue 19-dyes and antibacterial & antioxidant activities DOI

Valikala Viswanath,

Jayaprakash Meena,

E. Manikandamoorthy

et al.

International Journal of Environmental & Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 19

Published: Feb. 10, 2025

The green synthesis of zinc oxide (ZnO) nanomaterials is increasingly recognised in due to their minimal toxicity, high biocompatibility, and simple fabrication methods. This study presents the eco-friendly ZnO nanoparticles (ZnONPs) using Lilium lancifolium floral extract as a bio-reductant. Comprehensive physicochemical characterisation, including spectroscopic microscopic analyses, was conducted elucidate nanoparticles' structural morphological properties. ZnONPs displayed spherical hexagonal morphologies, consisting 49.34% oxygen 50.66% zinc. Zeta potential measurements indicated negative surface charge, BET disclosed specific area 35 m2/g, an average pore size ~ 25 nm, volume 0.74 cm3/g. Dynamic light scattering (DLS) revealed particle 27 nm polydispersity index (PDI) 0.332. antioxidant capacity ZnONPs, assessed through DPPH radical scavenging assays, showed activity ranging from 39.2% 71.2%, with IC50 47.2 µg/mL. performance surpassed (72.3 µg/mL) comparable ascorbic acid (IC50 = 37.4 µg/mL). Photocatalytic degradation studies on methyl violet (MV), Rhodamine B (RhB), reactive blue 19 (RBBR) dyes followed pseudo-first-order kinetics adhered Langmuir-Hinshelwood adsorption models. Additionally, lipid peroxidation inhibition assays demonstrated both preventing peroxidation, indicating promising antimicrobial properties for combating bacterial infections.

Language: Английский

Citations

0
Biosynthesis and Characterization of Mn3O4 Nanoparticles Using Bixa orellana and Nerium oleander Leaf Extracts at Low Temperature and Neutral pH DOI Creative Commons
Eiser Valle-Rivera, Segundo R. Jáuregui-Rosas, Sergio P. R. Avila-Concepción

et al.

Crystals, Journal Year: 2025, Volume and Issue: 15(3), P. 226 - 226

Published: Feb. 27, 2025

Mn3O4 nanoparticles have been synthesized using alcoholic extracts, at pH = 7 and low temperature (60 °C), from different masses (1.00, 3.00, 5.00, 7.00 g) of fresh leaves Nerium oleander Bixa orellana, without additional heat treatment. Appropriate techniques were used to identify the secondary metabolites extracts evaluate structural, optical, chemical properties nanoparticles. The XRD results confirmed formation with crystallite size in 5−8 nm range, more notable effects on crystallinity obtained B. orellana extracts. greatest effect bandgap was observed N. Raman spectra phonon confinement, PL spectra, emission bands associated structural defects, such as oxygen vacancies, observed. In FTIR main identified, whose intensity decreased concentration extract other functional groups increased. TEM images showed spherical 7.81 (N1) 7.94 (B1) average diameters. appropriate than that for synthesis under conditions used.

Language: Английский

Citations

0
Electrospun Polycaprolactone–Gelatin Fibrils Enabled 3D Hydrogel Microcapsules for Biomedical Applications DOI Creative Commons
Felix Tettey,

Thakur Sapkota,

Sita Shrestha

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(3), P. 85 - 85

Published: March 2, 2025

Microcapsules provide a microenvironment by improving the protection and delivery of cells drugs to specific tissue areas, promoting cell integration regeneration. Effective microcapsules must not only be permeable for micronutrient diffusion but mechanically stable. Alginate hydrogel is one commonly used biomaterials fabricating due its gel-forming ability low toxicity. However, mechanical instability, inertness, excessive porosity have impeded use. Embedding nanofibrils in alginate improves their biological properties. In this research, electrospun composite nanofibers PCL–gelatin (PG) were first fabricated, characterized, cryoground. The filtered cryoground powder solution was mixed with through electrospray, fabricated into microcapsules. Parameters such as flow rate, voltage, composition, which are critical electrostatic encapsulation process, optimized. further immersed different solvent environments (DI water, complete media, PBS), observed compared morphology, size distribution, stability average diameters PG ranged between 0.2 2 μm, an 58 73%. varied 300 900 depending on environment. Overall, results showed improved 3D network suitable biomedical applications.

Language: Английский

Citations

0
Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities DOI Creative Commons
Deepak Kumar Shrestha, Akash Budha Magar,

Manisha Bhusal

et al.

Journal of Chemistry, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

The present research involves a green synthesis of silver and zinc oxide nanoparticles using an aqueous extract Polystichum lentum comparison bioactivities. Phenolics, flavonoids, alkaloids, steroids, saponins were in the extract. highest TPC TFC found ethanol with 124.93 ± 9.36 mg GAE/g 28.73 1.98 QE/g. formation Ag ZnO NPs was confirmed by appearance peaks at 421 nm 362 UV‐visible spectra. involvement plant secondary metabolites nanoparticle indicated shifts peak positions intensities FTIR SEM XRD analyses established spherical morphology (average size 61.33 15.31 nm) FCC crystal structure for hexagonal to round 97.20 12.92 wurtzite NPs. EDX analysis revealed elemental composition nanoparticles. IC 50 values 51.95 3.11 83.79 6.63 μ g/mL DPPH assay significantly higher than 32.07 1.03 6.53 1.57 methanol extracts. showed comparatively ZOI 14 16 mm against Shigella sonnei Klebsiella pneumoniae. It also displayed lowest MIC MBC 3.125 6.25 mg/mL Staphylococcus aureus pneumoniae . exhibit potent cytotoxicity 76.82 1.67 cervical cancer cell lines. Both mildly toxic towards brine shrimp nauplii LC being 661.80 64.21 In conclusion, findings study demonstrate high antioxidant, antibacterial, anticancer activities synthesized

Language: Английский

Citations

2
In silico molecular docking and ADMET prediction of biogenic zinc oxide nanoparticles: characterization, and in vitro antimicrobial and photocatalytic activity DOI Creative Commons
Hajara Akhter,

Susmita Sarker Ritu,

Shahariar Siddique

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(49), P. 36209 - 36225

Published: Jan. 1, 2024

A facile green route to synthesize zinc oxide nanoparticles using watermelon rind extract with antimicrobial and photocatalytic potential.

Language: Английский

Citations

2
Biosynthesis of Zinc Oxide Nanoparticles Using Garlic Peel Extract and Their Antibacterial Potential DOI Creative Commons
Ali Abdelmoteleb, Benjamín Valdez, Ernesto Beltrán‐Partida

et al.

Microbiology Research, Journal Year: 2024, Volume and Issue: 15(3), P. 1655 - 1669

Published: Aug. 23, 2024

Zinc oxide nanoparticles (ZnO NPs) have gathered interest because of their unique characteristics and potential applications. In the current work, ZnO NPs underwent an eco-friendly biosynthesis process using garlic peel extract. The biosynthesized were characterized different analyses including Ultraviolet-visible (UV-vis) spectroscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), dynamic light scattering (DLS), Fourier transform infrared (FTIR). produced exhibited a UV–vis spectrum absorption peak at 365 nm, thus indicating formation NPs. SEM showed that had irregular surface morphological shape with average size 17 according to DLS analysis. Based on FTIR findings, bioactive functional groups responsible for stabilizing capping ZnO-NPs confirmed. 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity antimicrobial activities against Gram-positive (Bacillus cereus) Gram-negative bacteria (Klebsiella pneumonia). Therefore, plant-mediated ZnNPs can be considered promising candidate as antioxidant agent pathogenic microbes found in areas such food safety agriculture. Through utilization bioinformatics, we identified six targets drug development K. pneumonia B. cereus, along corresponding interacting residues zinc nanoparticles. Additionally, our research revealed binding capabilities sulfiredoxin domain located specific pneumonia, crucial mechanism repair bacterial cells under oxidative stress.

Language: Английский

Citations

1
Green Essence of Plant Resources Capped Zinc Oxide Nanoparticles: Renewable Distinctions, Size‐Shape‐Modulated Physicochemical Diversity and Emerging Biomedical‐Environmental Usefulness DOI Open Access
Parth Malik, Ruma Rani, Sharjeel Ahmed Khan

et al.

Particle & Particle Systems Characterization, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Abstract The natural essence, biocompatibility, and pleiotropic functioning of plant polyphenols have swiftly emerged as integrated assets for biomedical environmental applications resources capped ZnO NPs. Simultaneous reducing cum capping abilities, synergistic edible prospects, precursor‐plant extract stoichiometry‐driven robust size‐shape modulation are the major encouragements being explored increasing recent interest in biomedical‐environmental extracts (PEs) structure‐function dynamics from leaves, roots, fruits, seeds, whole plants sum up multifaceted polyphenols‐capped Recent resources' utility NPs mandates discussing correlative mechanisms sustainable future insights. PEs drug carriers sensing agents significantly moderate toxic chemotherapeutic intake via enhanced tumor cell internalization, aided by immune‐modulating actions constituent phytochemicals. On front, antioxidant features make them potent degrading degradation persisting effluents. Keeping above aspects mind, this review article focuses on underlying remediation made This would augment awareness consolidating understanding predictive mechanistic controls.

Language: Английский

Citations

0